Search Results - "Fernando, Laurent"
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Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia
Published in The Journal of experimental medicine (03-05-2021)“…Mutations in IDH induce epigenetic and transcriptional reprogramming, differentiation bias, and susceptibility to mitochondrial inhibitors in cancer cells…”
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Journal Article -
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Ranking Enzyme Structures in the PDB by Bound Ligand Similarity to Biological Substrates
Published in Structure (London) (03-04-2018)“…There are numerous applications that use the structures of protein-ligand complexes from the PDB, such as 3D pharmacophore identification, virtual screening,…”
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Journal Article