Search Results - "Fernandez Viña, Marcelo"
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The effect of donor characteristics on survival after unrelated donor transplantation for hematologic malignancy
Published in Blood (14-01-2016)“…There are >24 million registered adult donors, and the numbers of unrelated donor transplantations are increasing. The optimal strategy for prioritizing among…”
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High-throughput, high-fidelity HLA genotyping with deep sequencing
Published in Proceedings of the National Academy of Sciences - PNAS (29-05-2012)“…Human leukocyte antigen (HLA) genes are the most polymorphic in the human genome. They play a pivotal role in the immune response and have been implicated in…”
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Spherotech‐EDTA combined serum treatment reduces background more effectively as compared to One Lambda Adsorb Out™ and LIFECODES Serum Cleaner in Luminex‐based solid‐phase immunoassays for HLA antibody detection
Published in HLA (01-08-2023)“…Spherotech (SPT) microparticles capture non‐specific binding materials present in test serum, and EDTA removes the so called” prozone effect”. This study…”
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Identification of a permissible HLA mismatch in hematopoietic stem cell transplantation
Published in Blood (20-02-2014)“…In subjects mismatched in the HLA alleles C*03:03/C*03:04 no allogeneic cytotoxic T-lymphocyte responses are detected in vitro. Hematopoietic stem cell…”
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Capturing Differential Allele-Level Expression and Genotypes of All Classical HLA Loci and Haplotypes by a New Capture RNA-Seq Method
Published in Frontiers in immunology (29-05-2020)“…The highly polymorphic human major histocompatibility complex (MHC) also known as the human leukocyte antigen (HLA) encodes class I and II genes that are the…”
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Comparison of Risk-Based Hepatitis C Screening and the True Seroprevalence in an Urban Prison System
Published in Journal of urban health (01-04-2015)“…Hepatitis C virus (HCV) is the most common blood-borne infection in the USA, though seroprevalence is elevated in certain high-risk groups such as inmates…”
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Immunogenetics as a tool in anthropological studies
Published in Immunology (01-06-2011)“…Summary The genes coding for the main molecules involved in the human immune system – immunoglobulins, human leucocyte antigen (HLA) molecules and killer‐cell…”
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HLA class I and class II conserved extended haplotypes and their fragments or blocks in Mexicans: implications for the study of genetic diversity in admixed populations
Published in PloS one (23-09-2013)“…Major histocompatibility complex (MHC) genes are highly polymorphic and informative in disease association, transplantation, and population genetics studies…”
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Uncoupling the Roles of HLA-DRB1 and HLA-DRB5 Genes in Multiple Sclerosis
Published in The Journal of immunology (1950) (15-10-2008)“…Genetic susceptibility to multiple sclerosis (MS) is associated with the MHC located on chromosome 6p21. This signal maps primarily to a 1-Mb region…”
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Allelic resolution NGS HLA typing of Class I and Class II loci and haplotypes in Cape Town, South Africa
Published in Human immunology (01-12-2018)“…The development of next-generation sequencing (NGS) methods for HLA genotyping has already had an impact on the scope and precision of HLA research. In this…”
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Human leukocyte antigen supertype matching after myeloablative hematopoietic cell transplantation with 7/8 matched unrelated donor allografts: a report from the Center for International Blood and Marrow Transplant Research
Published in Haematologica (Roma) (01-10-2016)“…The diversity of the human leukocyte antigen (HLA) class I and II alleles can be simplified by consolidating them into fewer supertypes based on functional or…”
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HLA factors in transplantation for nonmalignant hematologic disorders
Published in Blood (04-10-2012)“…In this issue of Blood, a study by Horan and colleagues shows that differences in the HLA alleles of patients and unrelated donors in hematopoietic stem cell…”
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Identification of a Human HLA-E-Restricted CD8+ T Cell Subset in Volunteers Immunized with Salmonella enterica Serovar Typhi Strain Ty21a Typhoid Vaccine
Published in The Journal of immunology (1950) (01-11-2004)“…Our previous studies in volunteers immunized with Salmonella enterica serovar Typhi (S. Typhi) have suggested an important role for CD8+ T cells in host…”
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Concomitant Induction of CD4+ and CD8+ T Cell Responses in Volunteers Immunized with Salmonella enterica Serovar Typhi Strain CVD 908-htrA
Published in The Journal of immunology (1950) (01-03-2003)“…Type 1 cell-mediated immunity might play an important role in protection from typhoid fever. We evaluated whether immunization with Salmonella enterica serovar…”
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State Laws Governing Syringe Services Programs and Participant Syringe Possession, 2014-2019
Published in Public health reports (1974) (01-07-2020)“…Objective Law is an important factor in the diffusion of syringe services programs (SSPs). This study measures the current status of, and 5-year change in,…”
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Next-generation sequencing reveals new information about HLA allele and haplotype diversity in a large European American population
Published in Human immunology (01-10-2019)“…The human leukocyte antigen (HLA) genes are extremely polymorphic and are useful molecular markers to make inferences about human population history. However,…”
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Current HLA testing recommendations to support HCT
Published in Human immunology (01-10-2022)Get full text
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A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson’s disease
Published in Proceedings of the National Academy of Sciences - PNAS (09-04-2019)“…Parkinson’s disease (PD) is a neurodegenerative disease in which genetic risk has been mapped to HLA, but precise allelic associations have been difficult to…”
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Mixed chimerism and acceptance of kidney transplants after immunosuppressive drug withdrawal
Published in Science translational medicine (29-01-2020)“…Preclinical studies have shown that persistent mixed chimerism is linked to acceptance of organ allografts without immunosuppressive (IS) drugs. Mixed…”
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Exceptional diversity of KIR and HLA class I in Egypt
Published in HLA (01-01-2024)“…Genetically determined variation of killer cell immunoglobulin like receptors (KIR) and their HLA class I ligands affects multiple aspects of human health…”
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