Search Results - "Fernandez Garcia, Emily"
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The mitochondrial Ca2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation
Published in Frontiers in cell and developmental biology (08-06-2023)“…Introduction: The mitochondrial uniporter (MCU) Ca 2+ ion channel represents the primary means for Ca 2+ uptake by mitochondria. Mitochondrial matrix Ca 2+…”
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Abstract PO-026: The mitochondrial calcium uniporter contributes to PDAC development and invasion
Published in Cancer research (Chicago, Ill.) (15-11-2020)“…Pancreatic ductal adenocarcinoma (PDAC) has an exceptionally poor prognosis, with about 50,000 new cases and 45,000 deaths each year. While novel…”
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The MCU Inhibitor Ds16570511 has Off-Target Effects on Mitochondrial Membrane Potential
Published in Biophysical journal (15-02-2019)Get full text
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The mitochondrial Ca 2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation
Published in Frontiers in cell and developmental biology (2023)“…The mitochondrial uniporter (MCU) Ca ion channel represents the primary means for Ca uptake by mitochondria. Mitochondrial matrix Ca plays critical roles in…”
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Journal Article -
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Uncovering the lipidic basis for the preparation of functional nicotinic acetylcholine receptor detergent complexes for structural studies
Published in Scientific reports (19-09-2016)“…This study compares the lipid composition, including individual phospholipid molecular species of solubilized nAChR detergent complexes (nAChR-DCs) with those…”
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Journal Article -
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The Mitochondrial Ca2+ Channel MCU Is Critical for Tumor Growth by Supporting Cell Cycle Progression and Proliferation
Published 01-01-2023“…The mitochondrial uniporter (MCU) Ca2+ ion channel represents the primary means for Ca2+ uptake by mitochondria. Mitochondrial matrix Ca2+ plays critical roles…”
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Dissertation