Search Results - "Fernandez Curbelo, Irina"
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Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD
Published in Blood (25-09-2014)“…A subset of regulatory B cells (Bregs) in mice negatively regulate T-cell immune responses through the secretion of regulatory cytokines such as IL-10 and…”
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Ipilimumab plus Lenalidomide after Allogeneic and Autologous Stem Cell Transplantation for Patients with Lymphoid Malignancies
Published in Clinical cancer research (01-03-2018)“…Prevention or treatment of relapsed lymphoid malignancies after hematopoietic stem cell transplantation (HSCT) requires novel strategies. We hypothesized that…”
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Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
Published in Nature Medicine (01-08-2021)“…Treatment with combined immune checkpoint blockade (CICB) targeting CTLA-4 and PD-1 is associated with clinical benefit across tumor types, but also a high…”
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Characterization and Comparison of GITR Expression in Solid Tumors
Published in Clinical cancer research (01-11-2019)“…Determine the differential effect of a FcγR-binding, mIgG2a anti-GITR antibody in mouse tumor models, and characterize the tumor microenvironment for the…”
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Lenalidomide with Ipilimumab for Lymphoid Malignancies after Allogeneic or Autologous Stem Cell Transplantation (SCT)
Published in Blood (02-12-2016)“…Background: Prevention or treatment of relapse after SCT for lymphoid malignancies requires novel strategies. Targeting immune checkpoints could result in…”
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Journal Article