Search Results - "Fernandez‐Santos, María Eugenia"

Periodontal regeneration using a xenogeneic bone substitute seeded with autologous periodontal ligament‐derived mesenchymal stem cells: A 12‐month quasi‐randomized controlled pilot clinical trial by Sánchez, Nerea, Fierravanti, Ludovica, Núñez, Javier, Vignoletti, Fabio, González‐Zamora, María, Santamaría, Silvia, Suárez‐Sancho, Susana, Fernández‐Santos, María Eugenia, Figuero, Elena, Herrera, David, García‐Sanz, Jose A., Sanz, Mariano

“…Aim To evaluate the safety and efficacy of autologous periodontal ligament‐derived mesenchymal stem cells (PDL‐MSCs) embedded in a xenogeneic bone substitute…”
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Two phase I/II clinical trials for the treatment of urinary incontinence with autologous mesenchymal stem cells by Garcia‐Arranz, Mariano, Alonso‐Gregorio, Sergio, Fontana‐Portella, Pamela, Bravo, Elena, Diez Sebastian, Jesus, Fernandez‐Santos, María Eugenia, Garcia‐Olmo, Damian

“…We evaluated the safety and feasibility of adipose‐derived mesenchymal stem cells to treat endoscopically urinary incontinence after radical prostatectomy in…”
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Comparison of Different Bone Marrow–Derived Stem Cell Approaches in Reperfused STEMI by San Roman, J. Alberto, MD, PhD, Sánchez, Pedro L., MD, PhD, Villa, Adolfo, MD, PhD, Sanz-Ruiz, Ricardo, MD, Fernandez-Santos, María Eugenia, PhD, Gimeno, Federico, MD, PhD, Ramos, Benigno, MD, Arnold, Roman, MD, PhD, Serrador, Ana, MD, PhD, Gutiérrez, Hipólito, MD, Martin-Herrero, Francisco, MD, PhD, Rollán, María Jesús, MD, PhD, Fernández-Vázquez, Felipe, MD, PhD, López-Messa, Juan, MD, PhD, Ancillo, Pablo, MD, PhD, Pérez-Ojeda, German, MD, PhD, Fernández-Avilés, Francisco, MD, PhD

“…Abstract Background Stem cell–based therapy has emerged as a potential therapy in acute myocardial infarction (AMI). Although various approaches have been…”
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Natural Hydrogels Support Kidney Organoid Generation and Promote In Vitro Angiogenesis by Garreta, Elena, Moya‐Rull, Daniel, Marco, Andrés, Amato, Gaia, Ullate‐Agote, Asier, Tarantino, Carolina, Gallo, Maria, Esporrín‐Ubieto, David, Centeno, Alberto, Vilas‐Zornoza, Amaia, Mestre, Rafael, Kalil, María, Gorroñogoitia, Izar, Zaldua, Ane Miren, Sanchez, Samuel, Izquierdo Reyes, Laura, Fernández‐Santos, María Eugenia, Prosper, Felipe, Montserrat, Nuria

“…To date, strategies aiming to modulate cell to extracellular matrix (ECM) interactions during organoid derivation remain largely unexplored. Here renal…”
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Intracoronary Delivery of Porcine Cardiac Progenitor Cells Overexpressing IGF-1 and HGF in a Pig Model of Sub-Acute Myocardial Infarction by Prat-Vidal, Cristina, Crisóstomo, Verónica, Moscoso, Isabel, Báez-Díaz, Claudia, Blanco-Blázquez, Virginia, Gómez-Mauricio, Guadalupe, Albericio, Guillermo, Aguilar, Susana, Fernández-Santos, María-Eugenia, Fernández-Avilés, Francisco, Sánchez-Margallo, Francisco M, Bayes-Genis, Antoni, Bernad, Antonio

“…Human cardiac progenitor cells (hCPC) are considered a good candidate in cell therapy for ischemic heart disease, demonstrating capacity to improve functional…”
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Injection Laryngoplasty Using Autologous Fat Enriched with Adipose-Derived Regenerative Stem Cells: A Safe Therapeutic Option for the Functional Reconstruction of the Glottal Gap after Unilateral Vocal Fold Paralysis by García-Martín, Ana I., Gómez-Vilda, Pedro, Scola, Batolomé, Poletti, Daniel, Lasso, José M., Fernández Santos, María Eugenia

“…Background. Paralysis of one vocal fold leads to glottal gap and vocal fold insufficiency that has significant impact upon a patient’s quality of life. Fillers…”
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Optimization of Mesenchymal Stromal Cell (MSC) Manufacturing Processes for a Better Therapeutic Outcome by Fernández-Santos, Maria Eugenia, Garcia-Arranz, Mariano, Andreu, Enrique J., García-Hernández, Ana Maria, López-Parra, Miriam, Villarón, Eva, Sepúlveda, Pilar, Fernández-Avilés, Francisco, García-Olmo, Damian, Prosper, Felipe, Sánchez-Guijo, Fermin, Moraleda, Jose M., Zapata, Agustin G.

“…MSCs products as well as their derived extracellular vesicles, are currently being explored as advanced biologics in cell-based therapies with high…”
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Adipose-derived regenerative cells in patients with ischemic cardiomyopathy: The PRECISE Trial by Perin, Emerson C., MD, PhD, Sanz-Ruiz, Ricardo, MD, Sánchez, Pedro L., MD, PhD, Lasso, José, MD, PhD, Pérez-Cano, Rosa, MD, PhD, Alonso-Farto, Juan C., MD, PhD, Pérez-David, Esther, MD, PhD, Fernández-Santos, Maria Eugenia, PhD, Serruys, Patrick W., MD, PhD, Duckers, Henrick J., MD, PhD, Kastrup, Jens, MD, Chamuleau, Steven, MD, PhD, Zheng, Yi, MD, Silva, Guilherme V., MD, Willerson, James T., MD, PhD, Fernández-Avilés, Francisco, MD, PhD

“…Aims Adipose-derived regenerative cells (ADRCs) can be isolated from liposuction aspirates and prepared as fresh cells for immediate administration in cell…”
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Role of Hospital Exemption in Europe: position paper from the Spanish Advanced Therapy Network (TERAV) by Sánchez-Guijo, Fermín, Avendaño-Solá, Cristina, Badimón, Lina, Bueren, Juan A., Canals, Josep M., Delgadillo, Joaquim, Delgado, Julio, Eguizábal, Cristina, Fernández-Santos, María-Eugenia, García-Olmo, Damián, González-Aseguinolaza, Gloria, Juan, Manel, Martín, Francisco, Mata, Rosario, Montserrat, Nuria, Pérez-Martínez, Antonio, Pérez-Simón, José A., Prósper, Felipe, Urbano-Ispizua, Álvaro, Zapata, Agustín G., Sureda, Anna, Moraleda, José M.

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Cardiac Extracellular Matrix Hydrogel Enriched with Polyethylene Glycol Presents Improved Gelation Time and Increased On-Target Site Retention of Extracellular Vesicles by Gómez-Cid, Lidia, López-Donaire, María Luisa, Velasco, Diego, Marín, Víctor, González, María Isabel, Salinas, Beatriz, Cussó, Lorena, García, Ángel, Bravo, Susana Belén, Fernández-Santos, María Eugenia, Elvira, Carlos, Sierra, Johanna, Arroba, Ester, Bañares, Rafael, Grigorian-Shamagian, Lilian, Fernández-Avilés, Francisco

“…Stem-cell-derived extracellular vesicles (EVs) have demonstrated multiple beneficial effects in preclinical models of cardiac diseases. However, poor retention…”
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A Novel GMP Protocol to Produce High-Quality Treg Cells From the Pediatric Thymic Tissue to Be Employed as Cellular Therapy by Bernaldo-de-Quirós, Esther, Cózar, Beatriz, López-Esteban, Rocío, Clemente, Maribel, Gil-Jaurena, Juan Miguel, Pardo, Carlos, Pita, Ana, Pérez-Caballero, Ramón, Camino, Manuela, Gil, Nuria, Fernández-Santos, María Eugenia, Suarez, Susana, Pion, Marjorie, Martínez-Bonet, Marta, Correa-Rocha, Rafael

“…Due to their suppressive capacity, the adoptive transfer of regulatory T cells (Treg) has acquired a growing interest in controlling exacerbated inflammatory…”
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Phases I–III Clinical Trials Using Adult Stem Cells by Sanz-Ruiz, Ricardo, Gutiérrez Ibañes, Enrique, Arranz, Adolfo Villa, Fernández Santos, María Eugenia, Fernández, Pedro L. Sánchez, Fernández-Avilés, Francisco

“…First randomized clinical trials have demonstrated that stem cell therapy can improve cardiac recovery after the acute phase of myocardial ischemia and in…”
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Role of atrial tissue remodeling on rotor dynamics: an in vitro study by Climent, Andreu M, Guillem, María S, Fuentes, Lucia, Lee, Peter, Bollensdorff, Christian, Fernández-Santos, María Eugenia, Suárez-Sancho, Susana, Sanz-Ruiz, Ricardo, Sánchez, Pedro Luis, Atienza, Felipe, Fernández-Avilés, Francisco

“…The objective of this article is to present an in vitro model of atrial cardiac tissue that could serve to study the mechanisms of remodeling related to atrial…”
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Ranolazine-Mediated Attenuation of Mechanoelectric Feedback in Atrial Myocyte Monolayers by Del-Canto, Irene, Gómez-Cid, Lidia, Hernández-Romero, Ismael, Guillem, María S, Fernández-Santos, María Eugenia, Atienza, Felipe, Such, Luis, Fernández-Avilés, Francisco, Chorro, Francisco J, Climent, Andreu M

“…Mechanical stretch increases Na inflow into myocytes, related to mechanisms including stretch-activated channels or Na /H exchanger activation, involving Ca…”
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Functional Multipotency of Stem Cells: What Do We Need from Them in the Heart? by Sanchez, Pedro L, Sanz-Ruiz, Ricardo, Garcia, Alberto Nunez, Fernandez-Aviles, Francisco, Villanueva, Pablo Diez, Santos, Maria Eugenia Fernandez

“…After more than ten years of human research in the field of cardiac regenerative medicine, application of stem cells in different phases of ischemic heart…”
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Cardiovascular Diseases in the Digital Health Era: A Translational Approach from the Lab to the Clinic by Sánchez de la Nava, Ana María, Gómez-Cid, Lidia, Ríos-Muñoz, Gonzalo Ricardo, Fernández-Santos, María Eugenia, Fernández, Ana I., Arenal, Ángel, Sanz-Ruiz, Ricardo, Grigorian-Shamagian, Lilian, Atienza, Felipe, Fernández-Avilés, Francisco

“…Translational science has been introduced as the nexus among the scientific and the clinical field, which allows researchers to provide and demonstrate that…”
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Clinical grade production of IL‐15 stimulated NK cells for early infusion in adult AML patients undergoing haploidentical stem cell transplantation with post‐transplant cyclophosphamide by Rubio‐Azpeitia, Eva, Pérez‐Corral, Ana Maria, Dorado‐Herrero, Nieves, Monsalvo, Silvia, Pérez‐Balsera, Gonzalo, Fernández‐Santos, Maria Eugenia, Kwon, Mi, Oarbeascoa, Gillen, Bastos‐Oreiro, Mariana, Falero, Carmen, Pascual Izquierdo, Cristina, Muñoz‐Martínez, Cristina, Pérez‐Martínez, Antonio, Diez‐Martin, José Luis, Anguita, Javier

“…Background Allogeneic stem cell transplantation is the treatment of choice for acute myeloid leukemia (AML) patients. Unmanipulated haploidentical…”
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Global position paper on cardiovascular regenerative medicine by Fernández-Avilés, Francisco, Sanz-Ruiz, Ricardo, Climent, Andreu M, Badimon, Lina, Bolli, Roberto, Charron, Dominique, Fuster, Valentin, Janssens, Stefan, Kastrup, Jens, Kim, Hyo-Soo, Lüscher, Thomas F, Martin, John F, Menasché, Philippe, Simari, Robert D, Stone, Gregg W, Terzic, Andre, Willerson, James T, Wu, Joseph C

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Natural Hydrogels Support Kidney Organoid Generation and Promote In Vitro Angiogenesis (Adv. Mater. 34/2024) by Garreta, Elena, Moya‐Rull, Daniel, Marco, Andrés, Amato, Gaia, Ullate‐Agote, Asier, Tarantino, Carolina, Gallo, Maria, Esporrín‐Ubieto, David, Centeno, Alberto, Vilas‐Zornoza, Amaia, Mestre, Rafael, Kalil, María, Gorroñogoitia, Izar, Zaldua, Ane Miren, Sanchez, Samuel, Izquierdo Reyes, Laura, Fernández‐Santos, María Eugenia, Prosper, Felipe, Montserrat, Nuria

“…Kidney Organoids The potential benefit of kidney‐specific extracellular matrix (ECM) proteins to favor kidney organoid derivation and vascularization remains…”
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Rationale and Design of a Clinical Trial to Evaluate the Safety and Efficacy of Intracoronary Infusion of Allogeneic Human Cardiac Stem Cells in Patients With Acute Myocardial Infarction and Left Ventricular Dysfunction: The Randomized Multicenter Double-Blind Controlled CAREMI Trial (Cardiac Stem Cells in Patients With Acute Myocardial Infarction) by Sanz-Ruiz, Ricardo, Casado Plasencia, Ana, Borlado, Luis R, Fernández-Santos, María Eugenia, Al-Daccak, Reem, Claus, Piet, Palacios, Itziar, Sádaba, Rafael, Charron, Dominique, Bogaert, Jan, Mulet, Miguel, Yotti, Raquel, Gilaberte, Immaculada, Bernad, Antonio, Bermejo, Javier, Janssens, Stefan, Fernández-Avilés, Franciso

“…Stem cell therapy has increased the therapeutic armamentarium in the fight against ischemic heart disease and heart failure. The administration of exogenous…”
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