Search Results - "Fernandez, Soledad A."

Preclinical Toxicology of rQNestin34.5v.2: An Oncolytic Herpes Virus with Transcriptional Regulation of the ICP34.5 Neurovirulence Gene by Chiocca, E. Antonio, Nakashima, Hiroshi, Kasai, Kazue, Fernandez, Soledad A., Oglesbee, Michael

“…rQNestin34.5v.2 is an oncolytic herpes simplex virus 1 (oHSV) that retains expression of the neurovirulent ICP34.5 gene under glioma-selective transcriptional…”
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NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors by Alvarez-Breckenridge, Christopher A, Yu, Jianhua, Price, Richard, Wojton, Jeffrey, Pradarelli, Jason, Mao, Hsiaoyin, Wei, Min, Wang, Yan, He, Shun, Hardcastle, Jayson, Fernandez, Soledad A, Kaur, Balveen, Lawler, Sean E, Vivier, Eric, Mandelboim, Ofer, Moretta, Alessandro, Caligiuri, Michael A, Chiocca, E Antonio

“…Oncolytic virotherapy has been tested in cancer patients, but its efficacy is uncertain. Alvarez-Breckenridge et al . now report that in mouse models of…”
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Evaluating fentanyl test strips as a harm reduction strategy in rural and urban counties: study protocol for a randomized controlled trial by Short Mejia, Ashley, Smith, Gary A, Fernandez, Soledad A, Freisthler, Bridget, Grella, Christine, Michaels, Nichole L

“…Opioid-related fatalities are a leading cause of death in Ohio and nationally, with an increasing number of overdoses attributable to fentanyl. Rapid fentanyl…”
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Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele by Wu, Jinghai, Liu, Xin, Nayak, Sunayana G, Pitarresi, Jason R, Cuitiño, Maria C, Yu, Lianbo, Hildreth, 3rd, Blake E, Thies, Katie A, Schilling, Daniel J, Fernandez, Soledad A, Leone, Gustavo, Ostrowski, Michael C

“…The contribution of the tumor microenvironment to the development of pancreatic adenocarcinoma (PDAC) is unclear. The LSL-KrasG12D/+;LSL-p53R172H/+;Pdx-1-Cre…”
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Performance of model-based vs. permutation tests in the HEALing (Helping to End Addiction Long-termSM) Communities Study, a covariate-constrained cluster randomized trial by Tang, Xiaoyu, Heeren, Timothy, Westgate, Philip M, Feaster, Daniel J, Fernandez, Soledad A, Vandergrift, Nathan, Cheng, Debbie M

“…Background The HEALing (Helping to End Addiction Long-term.sup.SM) Communities Study (HCS) is a multi-site parallel group cluster randomized wait-list…”
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Stromal PTEN determines mammary epithelial response to radiotherapy by Sizemore, Gina M., Balakrishnan, Subhasree, Thies, Katie A., Hammer, Anisha M., Sizemore, Steven T., Trimboli, Anthony J., Cuitiño, Maria C., Steck, Sarah A., Tozbikian, Gary, Kladney, Raleigh D., Shinde, Neelam, Das, Manjusri, Park, Dongju, Majumder, Sarmila, Krishnan, Shiva, Yu, Lianbo, Fernandez, Soledad A., Chakravarti, Arnab, Shields, Peter G., White, Julia R., Yee, Lisa D., Rosol, Thomas J., Ludwig, Thomas, Park, Morag, Leone, Gustavo, Ostrowski, Michael C.

“…The importance of the tumor–associated stroma in cancer progression is clear. However, it remains uncertain whether early events in the stroma are capable of…”
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The Histone Deacetylase Inhibitor Valproic Acid Lessens NK Cell Action against Oncolytic Virus-Infected Glioblastoma Cells by Inhibition of STAT5/T-BET Signaling and Generation of Gamma Interferon by ALVAREZ-BRECKENRIDGE, Christopher A, JIANHUA YU, KAUR, Balveen, CALIGIURI, Michael A, ANTONIO CHIOCCA, E, PRICE, Richard, MIN WEI, YAN WANG, NOWICKI, Michal O, HA, Yoonhee P, BERGIN, Stephen, HWANG, Christine, FERNANDEZ, Soledad A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Indirubins Decrease Glioma Invasion by Blocking Migratory Phenotypes in Both the Tumor and Stromal Endothelial Cell Compartments by WILLIAMS, Shanté P, NOWICKI, Michal O, FANG LIU, PRESS, Rachael, GODLEWSKI, Jakub, ABDEL-RASOUL, Mahmoud, KAUR, Balveen, FERNANDEZ, Soledad A, CHIOCCA, E. Antonio, LAWLER, Sean E

“…Invasion and proliferation in neoplasia require the cooperation of tumor cell and endothelial compartments. Glycogen synthase kinase-3 (GSK-3) is increasingly…”
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Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia by Pitarresi, Jason R, Liu, Xin, Sharma, Sudarshana M, Cuitiño, Maria C, Kladney, Raleigh D, Mace, Thomas A, Donohue, Sydney, Nayak, Sunayana G, Qu, Chunjing, Lee, James, Woelke, Sarah A, Trela, Stefan, LaPak, Kyle, Yu, Lianbo, McElroy, Joseph, Rosol, Thomas J, Shakya, Reena, Ludwig, Thomas, Lesinski, Gregory B, Fernandez, Soledad A, Konieczny, Stephen F, Leone, Gustavo, Wu, Jinghai, Ostrowski, Michael C

“…Abstract Preclinical studies have suggested that the pancreatic tumor microenvironment both inhibits and promotes tumor development and growth. Here we…”
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Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo by Caserta, Enrico, Egriboz, Onur, Wang, Hui, Martin, Chelsea, Koivisto, Christopher, Pecót, Thierry, Kladney, Raleigh D, Shen, Changxian, Shim, Kang-Sup, Pham, Thac, Karikomi, Matthew K, Mauntel, Melissa J, Majumder, Sarmila, Cuitino, Maria C, Tang, Xing, Srivastava, Arunima, Yu, Lianbo, Wallace, Julie, Mo, Xiaokui, Park, Morag, Fernandez, Soledad A, Pilarski, Robert, La Perle, Krista M D, Rosol, Thomas J, Coppola, Vincenzo, Castrillon, Diego H, Timmers, Cynthia, Cohn, David E, O'Malley, David M, Backes, Floor, Suarez, Adrian A, Goodfellow, Paul, Chamberlin, Helen M, Macrae, Erin R, Shapiro, Charles L, Ostrowski, Michael C, Leone, Gustavo

“…Inactivation of phosphatase and tensin homology deleted on chromosome 10 (PTEN) is linked to increased PI3K-AKT signaling, enhanced organismal growth, and…”
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E2f3a and E2f3b Contribute to the Control of Cell Proliferation and Mouse Development by Chong, Jean-Leon, Tsai, Shih-Yin, Sharma, Nidhi, Opavsky, Rene, Price, Richard, Wu, Lizhao, Fernandez, Soledad A., Leone, Gustavo

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human bone marrow stromal cells enhance breast cancer cell growth rates in a cell line-dependent manner when evaluated in 3D tumor environments by Sasser, A. Kate, Mundy, Bethany L, Smith, Kristen M, Studebaker, Adam W, Axel, Amy E, Haidet, Amanda M, Fernandez, Soledad A, Hall, Brett M

“…Abstract Our understanding of the impact that fibroblasts have on cancer cell behavior in vivo has been limited by the complexities of in vivo tumor…”
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Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer by Wallace, Julie A, Li, Fu, Balakrishnan, Subhasree, Cantemir-Stone, Carmen Z, Pecot, Thierry, Martin, Chelsea, Kladney, Raleigh D, Sharma, Sudarshana M, Trimboli, Anthony J, Fernandez, Soledad A, Yu, Lianbo, Rosol, Thomas J, Stromberg, Paul C, Lesurf, Robert, Hallett, Michael, Park, Morag, Leone, Gustavo, Ostrowski, Michael C

“…Tumor fibroblasts are active partners in tumor progression, but the genes and pathways that mediate this collaboration are ill-defined. Previous work…”
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Allele-specific tumor spectrum in Pten knockin mice by Wang, Hui, Karikomi, Matt, Naidu, Shan, Rajmohan, Ravi, Caserta, Enrico, Chen, Hui-Zi, Rawahneh, Maysoon, Moffitt, Julie, Stephens, Julie A, Fernandez, Soledad A, Weinstein, Michael, Wang, Danxin, Sadee, Wolfgang, La Perle, Krista, Stromberg, Paul, Rosol, Thomas J, Eng, Charis, Ostrowski, Michael C, Leone, Gustavo

“…Germline mutations in the tumor suppressor gene PTEN (phosphatase and tensin homology deleted on chromosome 10) cause Cowden and Bannayan-Riley-Ruvalcaba (BRR)…”
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Effects of Short-Term Zoledronic Acid Treatment on Bone Remodeling and Healing at Surgical Sites in the Maxilla and Mandible of Aged Dogs by Huja, Sarandeep S., DDS, PhD, Mason, Amin, DDS, Fenell, Celia E., BS, Mo, X., PhD, MAS, Hueni, Sarah, BS, MS, D'Atri, Andrew M., BS, Fernandez, Soledad A., PhD

“…Purpose It is unknown whether zoledronic acid (ZA) interferes with initial bone healing at extraction and implant sites. The goal of this study was to examine…”
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Rapid Fluid Resuscitation in Pediatrics: Testing the American College of Critical Care Medicine Guideline by Stoner, Michael J., MD, Goodman, Deborah G., RN, Cohen, Daniel M., MD, Fernandez, Soledad A., PhD, Hall, Mark W., MD

“…Study objective The 2002 American College of Critical Care Medicine (ACCM) guidelines for the resuscitation of pediatric septic shock suggest that 20 mL/kg of…”
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Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis by Opavsky, Rene, Tsai, Shih-Yin, Guimond, Martin, Arora, Anjulie, Opavska, Jana, Becknell, Brian, Kaufmann, Michael, Walton, Nathaniel A, Stephens, Julie A, Fernandez, Soledad A, Muthusamy, Natarajan, Felsher, Dean W, Porcu, Pierluigi, Caligiuri, Michael A, Leone, Gustavo

“…Deregulation of the Myc pathway and deregulation of the Rb pathway are two of the most common abnormalities in human malignancies. Recent in vitro experiments…”
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Toxicology and Biodistribution Studies for MGH2.1, an Oncolytic Virus that Expresses Two Prodrug-activating Genes, in Combination with Prodrugs by Kasai, Kazue, Nakashima, Hiroshi, Liu, Fang, Kerr, Samantha, Wang, Jiang, Phelps, Mitch, Potter, Philip M, Goins, William B, Fernandez, Soledad A, Chiocca, E Antonio

“…MGH2.1 is a herpes simplex virus type 1 (HSV1) oncolytic virus that expresses two prodrug-activating transgenes: the cyclophosphamide (CPA)-activating…”
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Pten in stromal fibroblasts suppresses mammary epithelial tumours by Leone, Gustavo, Chong, Jean-Leon, Stromberg, Paul C, Weinstein, Michael B, Ostrowski, Michael C, Creasap, Nicholas, Hallett, Michael, Sharma, Sudarshana M, Li, Fu, Wallace, Julie A, Cantemir-Stone, Carmen Z, Thompson, John C, Fernandez, Soledad A, Pepin, Francois, Merchant, Anand, Caserta, Enrico, Naidu, Shan, Trimboli, Anthony J, Barsky, Sanford H, Yee, Lisa, Wang, Hui, Rosol, Thomas J, Park, Morag, Gurcan, Metin N, Robinson, Michael L, Wei, Guo, Stephens, Julie A

“…The tumour stroma is believed to contribute to some of the most malignant characteristics of epithelial tumours. However, signalling between stromal and tumour…”
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Functional Comparison of HBZ and the Related APH-2 Protein Provides Insight into Human T-Cell Leukemia Virus Type 1 Pathogenesis by Panfil, Amanda R, Dissinger, Nathan J, Howard, Cory M, Murphy, Brandon M, Landes, Kristina, Fernandez, Soledad A, Green, Patrick L

“…Human T-cell leukemia virus type 1 (HTLV-1) and type 2 (HTLV-2) are highly related retroviruses that transform T cells in vitro but have distinct pathological…”
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