Search Results - "Fernandez, Rosario"

Asymmetric Synthesis of Axially Chiral C−N Atropisomers by Rodríguez‐Salamanca, Patricia, Fernández, Rosario, Hornillos, Valentín, Lassaletta, José M.

“…Molecules with restricted rotation around a single bond or atropisomers are found in a wide number of natural products and bioactive molecules as well as in…”
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Ir-Catalyzed Atroposelective Desymmetrization of Heterobiaryls: Hydroarylation of Vinyl Ethers and Bicycloalkenes by Romero-Arenas, Antonio, Hornillos, Valentín, Iglesias-Sigüenza, Javier, Fernández, Rosario, López-Serrano, Joaquín, Ros, Abel, Lassaletta, José M

“…A highly regio-, diastereo-, and enantioselective, scalable Ir-catalyzed hydroarylation of electron-rich acyclic and tensioned cyclic olefins with…”
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Synthesis of IAN-type N,N-Ligands via Dynamic Kinetic Asymmetric Buchwald–Hartwig Amination by Ramírez-López, Pedro, Ros, Abel, Romero-Arenas, Antonio, Iglesias-Sigüenza, Javier, Fernández, Rosario, Lassaletta, José M

“…The Pd0-catalyzed coupling of racemic heterobiaryl bromides, triflates, or nonaflates with aryl/alkyl primary amines using QUINAP as the ligand provides the…”
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Dynamic Kinetic Cross-Coupling Strategy for the Asymmetric Synthesis of Axially Chiral Heterobiaryls by Ros, Abel, Estepa, Beatriz, Ramírez-López, Pedro, Álvarez, Eleuterio, Fernández, Rosario, Lassaletta, José M

“…A dynamic kinetic asymmetric transformation (DYKAT) technique has been designed for the synthesis of 2′-substituted 2-aryl pyridines/iso­quinolines and related…”
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Progressive alterations in polysomal architecture and activation of ribosome stalling relief factors in a mouse model of Huntington's disease by Martin-Solana, Eva, Diaz-Lopez, Irene, Mohamedi, Yamina, Ventoso, Ivan, Fernandez, Jose-Jesus, Fernandez-Fernandez, Maria Rosario

“…Given their highly polarized morphology and functional singularity, neurons require precise spatial and temporal control of protein synthesis. Alterations in…”
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Asymmetric Dearomatization of Phthalazines by Anion-Binding Catalysis by Velázquez, Marta, Fernández, Rosario, Lassaletta, José M., Monge, David

“…A straightforward methodology for the enantioselective synthesis of 1,2-dihydrophthalazines via dearomatization of phthalazines by anion-binding catalysis has…”
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Isolation, culture and characterization of primary mouse RPE cells by Fernandez-Godino, Rosario, Garland, Donita L, Pierce, Eric A

“…This protocol describes the isolation and culture of primary mouse RPE cells from various mouse models to produce viable RPE cells in vitro that mimic in vivo…”
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A Dynamic Kinetic C–P Cross–Coupling for the Asymmetric Synthesis of Axially Chiral P,N Ligands by Ramírez-López, Pedro, Ros, Abel, Estepa, Beatriz, Fernández, Rosario, Fiser, Béla, Gómez-Bengoa, Enrique, Lassaletta, José M

“…The Pd-catalyzed enantioselective C–P cross-coupling between racemic, configurationally stable heterobiaryl triflates and…”
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Dynamic Kinetic Resolution of Indole-Based Sulfenylated Heterobiaryls by Rhodium-Catalyzed Atroposelective Reductive Aldol Reaction by Rodríguez-Franco, Carlos, Ros, Abel, Merino, Pedro, Fernández, Rosario, Lassaletta, José M., Hornillos, Valentín

“…A highly enantio- and diastereoselective dynamic kinetic resolution (DKR) of configurationally labile 3-aryl indole-2-carbaldehydes is described. The DKR…”
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C2-Symmetric Bis-Hydrazones as Ligands in the Asymmetric Suzuki−Miyaura Cross-Coupling by BERMEJO, Antonio, ROS, Abel, FERNÁNDEZ, Rosario, LASSALETTA, José M.

“…Glyoxal bis-hydrazone derived from (S,S)-1-amino-2,5-diphenylpyrrolidine behaves as an excellent ligand for phosphine-free, asymmetric Suzuki-Miyaura cross…”
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Dynamic Kinetic Asymmetric Heck Reaction for the Simultaneous Generation of Central and Axial Chirality by Carmona, José A, Hornillos, Valentín, Ramírez-López, Pedro, Ros, Abel, Iglesias-Sigüenza, Javier, Gómez-Bengoa, Enrique, Fernández, Rosario, Lassaletta, José M

“…A highly diastereo- and enantioselective, scalable Pd-catalyzed dynamic kinetic asymmetric Heck reaction of heterobiaryl sulfonates with electron-rich olefins…”
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Protective neuronal induction of ATF5 in endoplasmic reticulum stress induced by status epilepticus by TORRES-PERAZA, Jesus F, ENGEL, Tobias, MARTIN-IBANEZ, Raquel, SANZ-RODRIGUEZ, Amaya, ROSARIO FERNANDEZ-FERNANDEZ, M, ESGLEAS, Miriam, CANALS, Josep M, HENSHALL, David C, LUCAS, José J

“…Activating transcription factor 5 (ATF5) is a basic-leucine-zipper transcription factor of the ATF/CREB family. The Atf5 gene generates two transcripts, Atf5α…”
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Axially Chiral Triazoloisoquinolin-3-ylidene Ligands in Gold(I)-Catalyzed Asymmetric Intermolecular (4 + 2) Cycloadditions of Allenamides and Dienes by Francos, Javier, Grande-Carmona, Francisca, Faustino, Hélio, Iglesias-Sigüenza, Javier, Díez, Elena, Alonso, Isaac, Fernández, Rosario, Lassaletta, José M, López, Fernando, Mascareñas, José L

“…The first highly enantioselective intermolecular (4 + 2) cycloaddition between allenes and dienes is reported. The reaction provides good yields of optically…”
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Hydrazone as the Directing Group for Ir-Catalyzed Arene Diborylations and Sequential Functionalizations by Ros, Abel, López-Rodríguez, Rocío, Estepa, Beatriz, Álvarez, Eleuterio, Fernández, Rosario, Lassaletta, José M

“…The use of hemilabile pyridine–hydrazone N,N-ligands allows the highly selective Ir-catalyzed ortho,ortho′-directed diborylation of aromatic…”
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Ir-Catalyzed Asymmetric Hydroarylation of Alkynes for the Synthesis of Axially Chiral Heterobiaryls by Vázquez-Domínguez, Pablo, Romero-Arenas, Antonio, Fernández, Rosario, Lassaletta, José María, Ros, Abel

“…The catalytic hydroarylation of alkynes has emerged as an excellent methodology for the synthesis of functionalized alkenes with excellent levels of regio- and…”
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Tick‐over‐mediated complement activation is sufficient to cause basal deposit formation in cell‐based models of macular degeneration by Chinchilla, Blanca, Foltopoulou, Parthena, Fernandez‐Godino, Rosario

“…Despite numerous unsuccessful clinical trials for anti‐complement drugs to treat age‐related macular degeneration (AMD), the complement system has not been…”
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Enantio‐ and Diastereoselective Nucleophilic Addition of N‐tert‐Butylhydrazones to Isoquinolinium Ions through Anion‐Binding Catalysis by Matador, Esteban, Iglesias‐Sigüenza, Javier, Monge, David, Merino, Pedro, Fernández, Rosario, Lassaletta, José M.

“…A highly enantio‐ and diastereoselective thiourea‐catalyzed dearomatization of isoquinolines employing N‐tert‐butylhydrazones as neutral α‐azo carbanions and…”
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Steady-Sensitivity Distributed Acoustic Sensors by Fernandez-Ruiz, Maria Rosario, Martins, Hugo F., Costa, Luis, Martin-Lopez, Sonia, Gonzalez-Herraez, Miguel

“…Distributed acoustic sensors (DAS) based on phase-sensitive optical time-domain reflectometry (φOTDR) have demonstrated interesting performance for many…”
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Dynamic Kinetic Resolution of Heterobiaryl Ketones by Zinc‐Catalyzed Asymmetric Hydrosilylation by Hornillos, Valentín, Carmona, José A., Ros, Abel, Iglesias‐Sigüenza, Javier, López‐Serrano, Joaquín, Fernández, Rosario, Lassaletta, José M.

“…A diastereo‐ and highly enantioselective dynamic kinetic resolution (DKR) of configurationally labile heterobiaryl ketones is described. The DKR proceeds by…”
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Biocatalytic Atroposelective Synthesis of Axially Chiral N‑Arylindoles via Dynamic Kinetic Resolution by Rodríguez-Salamanca, Patricia, de Gonzalo, Gonzalo, Carmona, José A., López-Serrano, Joaquín, Iglesias-Sigüenza, Javier, Fernández, Rosario, Lassaletta, José M., Hornillos, Valentín

“…A highly enantioselective biocatalytic dynamic kinetic resolution (DKR) of configurationally labile N-arylindole aldehydes is described. The DKR proceeds by…”
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