Search Results - "Fernandez, Lara P"

Alterations of Lipid Metabolism in Cancer: Implications in Prognosis and Treatment by Fernández, Lara P., Gómez de Cedrón, Marta, Ramírez de Molina, Ana

“…Cancer remains the second leading cause of mortality worldwide. In the course of this multistage and multifactorial disease, a set of alterations takes place,…”
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The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis by Riesco-Eizaguirre, Garcilaso, Wert-Lamas, León, Perales-Patón, Javier, Sastre-Perona, Ana, Fernández, Lara P, Santisteban, Pilar

“…The presence of differentiated thyroid cells in thyroid cancer is critical for the antitumor response to radioactive iodide treatment, and loss of the…”
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FOXE1 regulates migration and invasion in thyroid cancer cells and targets ZEB1 by Morillo-Bernal, Jesús, Fernández, Lara P, Santisteban, Pilar

“…FOXE1 is a thyroid-specific transcription factor essential for thyroid gland development and maintenance of the differentiated state. Interestingly, a strong…”
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Precision Nutrition for Targeting Lipid Metabolism in Colorectal Cancer by Aguirre-Portoles, Cristina, Fernandez, Lara P, Ramírez de Molina, Ana

“…Cancer is a multistage and multifactorial condition with genetic and environmental factors modulating tumorogenesis and disease progression. Nevertheless,…”
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Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3' untranslated region by Fernández, Lara P, Deleyto-Seldas, Nerea, Colmenarejo, Gonzalo, Sanz, Alba, Wagner, Sonia, Plata-Gómez, Ana Belén, Gómez-Patiño, Mónica, Molina, Susana, Espinosa-Salinas, Isabel, Aguilar-Aguilar, Elena, Ortega, Sagrario, Graña-Castro, Osvaldo, Loria-Kohen, Viviana, Fernández-Marcos, Pablo J, Efeyan, Alejo, Ramírez de Molina, Ana

“…Overweight and obesity are defined by an anomalous or excessive fat accumulation that may compromise health. To find single-nucleotide polymorphisms (SNPs)…”
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New insights into FoxE1 functions: identification of direct FoxE1 targets in thyroid cells by Fernández, Lara P, López-Márquez, Arístides, Martínez, Angel M, Gómez-López, Gonzalo, Santisteban, Pilar

“…FoxE1 is a thyroid-specific forkhead transcription factor essential for thyroid gland development, as well as for the maintenance of the thyroid differentiated…”
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The role of glycosyltransferase enzyme GCNT3 in colon and ovarian cancer prognosis and chemoresistance by Fernández, Lara P., Sánchez-Martínez, Ruth, Vargas, Teodoro, Herranz, Jesús, Martín-Hernández, Roberto, Mendiola, Marta, Hardisson, David, Reglero, Guillermo, Feliu, Jaime, Redondo, Andrés, Ramírez de Molina, Ana

“…Glycosyltransferase enzyme GCNT3, has been proposed as a biomarker for prognosis in colorectal cancer (CRC). Our study goes in depth into the molecular basis…”
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Non-Coding and Regulatory RNAs as Epigenetic Remodelers of Fatty Acid Homeostasis in Cancer by Cruz-Gil, Silvia, Fernández, Lara P., Sánchez-Martínez, Ruth, Gómez de Cedrón, Marta, Ramírez de Molina, Ana

“…Cancer cells commonly display metabolic fluctuations. Together with the Warburg effect and the increased glutaminolysis, alterations in lipid metabolism…”
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Metabolic Health Together with a Lipid Genetic Risk Score Predicts Survival of Small Cell Lung Cancer Patients by Fernández, Lara P, Merino, María, Colmenarejo, Gonzalo, Moreno Rubio, Juan, González Pessolani, Tais, Reglero, Guillermo, Casado, Enrique, Sereno, María, Ramírez de Molina, Ana

“…Small cell lung cancer (SCLC) prognosis is the poorest of all types of lung cancer. Its clinical management remains heterogeneous and therefore, the capability…”
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Thyroid transcription factors in development, differentiation and disease by Fernández, Lara P., López-Márquez, Arístides, Santisteban, Pilar

“…Key Points Homeobox protein Nkx2.1 (NKX2-1), forkhead box protein E1 (FOXE1), paired box protein Pax8 (PAX8) and haematopoietically-expressed homeobox protein…”
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Genetic analysis of the vitamin D receptor gene in two epithelial cancers: melanoma and breast cancer case-control studies by Barroso, Eva, Fernandez, Lara P, Milne, Roger L, Pita, Guillermo, Sendagorta, Elena, Floristan, Uxua, Feito, Marta, Aviles, Jose A, Martin-Gonzalez, Manuel, Arias, Jose I, Zamora, Pilar, Blanco, Monserrat, Lazaro, Pablo, Benitez, Javier, Ribas, Gloria

“…Vitamin D serum levels have been found to be related to sun exposure and diet, together with cell differentiation, growth control and consequently, cancer…”
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The transcriptional and mutational landscapes of lipid metabolism-related genes in colon cancer by Fernández, Lara P, Ramos-Ruiz, Ricardo, Herranz, Jesús, Martín-Hernández, Roberto, Vargas, Teodoro, Mendiola, Marta, Guerra, Laura, Reglero, Guillermo, Feliu, Jaime, Ramírez de Molina, Ana

“…Metabolic alterations encountered in tumors are well recognized and considered as a hallmark of cancer. In addition to Warburg Effect, epidemiological and…”
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MC1R , SLC45A2 and TYR genetic variants involved in melanoma susceptibility in Southern European populations: Results from a Meta-analysis by Ibarrola-Villava, Maider, Hu, Hui-Han, Guedj, Mickaël, Fernandez, Lara P, Descamps, Vincent, Basset-Seguin, Nicole, Bagot, Martine, Benssussan, Armand, Saiag, Philippe, Fargnoli, Maria Concetta, Peris, Ketty, Aviles, Jose A, Lluch, Ana, Ribas, Gloria, Soufir, Nadem

“…Abstract Background and methods Seven genetic biomarkers previously associated with melanoma were analysed in a meta-analysis conducted in three South European…”
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Genetic polymorphisms in DNA repair and oxidative stress pathways associated with malignant melanoma susceptibility by Ibarrola-Villava, Maider, Peña-Chilet, Maria, Fernandez, Lara P, Aviles, Jose A, Mayor, Matias, Martin-Gonzalez, Manuel, Gomez-Fernandez, Cristina, Casado, Beatriz, Lazaro, Pablo, Lluch, Ana, Benitez, Javier, Lozoya, Rafael, Boldo, Enrique, Pizarro, Angel, Martinez-Cadenas, Conrado, Ribas, Gloria

“…Abstract Background Base excision repair (BER) and nucleotide excision repair (NER) pathways eliminate a wide variety of DNA damage, including UV…”
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Sex-specific genetic effects associated with pigmentation, sensitivity to sunlight, and melanoma in a population of Spanish origin by Hernando, Barbara, Ibarrola-Villava, Maider, Fernandez, Lara P, Peña-Chilet, Maria, Llorca-Cardeñosa, Marta, Oltra, Sara S, Alonso, Santos, Boyano, Maria Dolores, Martinez-Cadenas, Conrado, Ribas, Gloria

“…Human pigmentation is a polygenic quantitative trait with high heritability. In addition to genetic factors, it has been shown that pigmentation can be…”
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Pigmentation-related genes and their implication in malignant melanoma susceptibility by Fernandez, Lara P., Milne, Roger L., Pita, Guillermo, Floristan, Uxua, Sendagorta, Elena, Feito, Marta, Avilés, Jose A., Martin-Gonzalez, Manuel, Lázaro, Pablo, Benítez, Javier, Ribas, Gloria

“…:  Human pigmentation appears to be one of the main modulators of individual risk of developing malignant melanoma (MM). A large number of genes are known to…”
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Cognitive assessment protocol design in the ISSYS (Investigating Silent Strokes in hYpertensives: A magnetic resonance imaging Study) by Riba, I, Jarca, C.I, Mundet, X, Tovar, J.L, Orfila, F, Nafría, C, Raga, A, Girona, A, Fernández-Lara, P, Castañé, X, Álvarez Sabin, J, Fernández Cortiñas, I, Maisterra, O, Montaner, J, Delgado, P

“…Abstract Hypertension and silent cerebrovascular lesions (SCL) detected by brain magnetic resonance imaging (MRI) are associated with an increased risk of…”
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Genetic analysis of three important genes in pigmentation and melanoma susceptibility: CDKN2A, MC1R and HERC2/OCA2 by Ibarrola-Villava, Maider, Fernandez, Lara P., Pita, Guillermo, Bravo, Jerónimo, Floristan, Uxua, Sendagorta, Elena, Feito, Marta, Avilés, José A., Martin-Gonzalez, Manuel, Lázaro, Pablo, Benítez, Javier, Ribas, Gloria

“…Please cite this paper as: Genetic analysis of three important genes in pigmentation and melanoma susceptibility: CDKN2A, MC1R and HERC2/OCA2. Experimental…”
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Human beta-defensins (HBD1 and HBD3) and malignant melanoma susceptibility by Fernandez, Lara P, Milne, Roger L, Pita, Guillermo, Floristan, Uxua, Sendagorta, Elena, Feito, Marta, Aviles, Jose A, Martin-Gonzalez, Manuel, Lázaro, Pablo, Benítez, Javier, Ribas, Gloria

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Evaluating HapMap SNP data transferability in a large-scale genotyping project involving 175 cancer-associated genes by RIBAS, Gloria, GONZALEZ-NEIRA, Anna, ROBLEDO, Mercedes, CARRACEDO, Angel, BENITEZ, Javier, SALAS, Antonio, MILNE, Roger L, VEGA, Ana, CARRACEDO, Begona, GONZALEZ, Emilio, BARROSO, Eva, FERNANDEZ, Lara P, YANKILEVICH, Patricio

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