Search Results - "Fernandez, Julio"

On the origin of the Kreutz family of sungrazing comets by Fernández, Julio A, Lemos, Pablo, Gallardo, Tabaré

“…ABSTRACT We evaluate numerically three different models for the parent comet of the Kreutz family of sungrazers: (i) A Centaur on a highly inclined or…”
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Protein Folding Drives Disulfide Formation by Kosuri, Pallav, Alegre-Cebollada, Jorge, Feng, Jason, Kaplan, Anna, Inglés-Prieto, Alvaro, Badilla, Carmen L., Stockwell, Brent R., Sanchez-Ruiz, Jose M., Holmgren, Arne, Fernández, Julio M.

“…PDI catalyzes the oxidative folding of disulfide-containing proteins. However, the sequence of reactions leading to a natively folded and oxidized protein…”
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On the observed excess of large Mars-crossers in high-inclination orbits by Fernández, Julio A., Helal, Michel

“…Mars-crossing asteroids (MCAs) constitute a population of transient bodies coming from the asteroid belt that end up in the near-Earth region or are ejected…”
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Jupiter family comets in near-Earth orbits: Are some of them interlopers from the asteroid belt? by Fernández, Julio A., Sosa, Andrea

“…We analyze a sample of 58 Jupiter family comets (JFCs) in near-Earth orbits, defined as those whose perihelion distances at the time of discovery were…”
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The relationship between depression and frailty syndrome: a systematic review by Buigues, Cristina, Padilla-Sánchez, Celia, Garrido, Julio Fernández, Navarro-Martínez, Rut, Ruiz-Ros, Vicente, Cauli, Omar

“…Objectives: Frailty is a geriatric syndrome characterised by the clinical presentation of identifiable physical alterations such as loss of muscle mass and…”
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Dynamical evolution and end states of active and inactive Centaurs by Fernández, Julio A., Helal, Michel, Gallardo, Tabaré

“…We numerically study the dynamical evolution of observed samples of active and inactive Centaurs and clones that reach the Jupiter-Saturn region. Our aim is to…”
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Stretching Single Talin Rod Molecules Activates Vinculin Binding by del Rio, Armando, Perez-Jimenez, Raul, Liu, Ruchuan, Roca-Cusachs, Pere, Fernandez, Julio M, Sheetz, Michael P

“…The molecular mechanism by which a mechanical stimulus is translated into a chemical response in biological systems is still unclear. We show that mechanical…”
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Masses of long-period comets derived from non-gravitational effects - analysis of the computed results and the consistency and reliability of the non-gravitational parameters by Sosa, Andrea, Fernández, Julio A.

“…We estimate masses for a selected sample of long-period comets (LPCs) (with orbital periods P > 1000 yr and perihelion distances q < 2 au), with good…”
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Disulfide isomerization reactions in titin immunoglobulin domains enable a mode of protein elasticity by Giganti, David, Yan, Kevin, Badilla, Carmen L., Fernandez, Julio M., Alegre-Cebollada, Jorge

“…The response of titin to mechanical forces is a major determinant of the function of the heart. When placed under a pulling force, the unstructured regions of…”
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A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues by Rivas-Pardo, Jaime Andrés, Li, Yong, Mártonfalvi, Zsolt, Tapia-Rojo, Rafael, Unger, Andreas, Fernández-Trasancos, Ángel, Herrero-Galán, Elías, Velázquez-Carreras, Diana, Fernández, Julio M., Linke, Wolfgang A., Alegre-Cebollada, Jorge

“…Single-molecule methods using recombinant proteins have generated transformative hypotheses on how mechanical forces are generated and sensed in biological…”
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The end states of long-period comets and the origin of Halley-type comets by Fernández, Julio A., Gallardo, Tabaré, Young, Juan D.

“…We analyse a sample of 73 old long-period comets (LPCs) (orbital periods 200 < P < 1000 yr) with perihelion distances q < 2.5 au, discovered in the period…”
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Identical sequences, different behaviors: Protein diversity captured at the single-molecule level by Tapia-Rojo, Rafael, Alonso-Caballero, Alvaro, Badilla, Carmen L, Fernandez, Julio M

“…The classical "one sequence, one structure, one function" paradigm has shaped much of our intuition of how proteins work inside the cell. Partially due to the…”
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Dynamics of Equilibrium Folding and Unfolding Transitions of Titin Immunoglobulin Domain under Constant Forces by Chen, Hu, Yuan, Guohua, Winardhi, Ricksen S, Yao, Mingxi, Popa, Ionel, Fernandez, Julio M, Yan, Jie

“…The mechanical stability of force-bearing proteins is crucial for their functions. However, slow transition rates of complex protein domains have made it…”
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AMOC decline and recovery in a warmer climate by Nobre, Paulo, Veiga, Sandro F., Giarolla, Emanuel, Marquez, André L., da Silva, Manoel B., Capistrano, Vinícius B., Malagutti, Marta, Fernandez, Julio P. R., Soares, Helena C., Bottino, Marcus J., Kubota, Paulo Y., Figueroa, Silvio N., Bonatti, José P., Sampaio, Gilvan, Casagrande, Fernanda, Costa, Mabel C., Nobre, Carlos A.

“…This study presents novel insight into the mechanisms of Atlantic Meridional Overturning Circulation (AMOC) reduction and its recovery under a warmer climate…”
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‘En Bloc’ HoLEP with early apical release in men with benign prostatic hyperplasia by Saitta, Giuseppe, Becerra, José Ernesto Aguayo, del Álamo, Julio Fernández, González, Luis Llanes, Elbers, Javier Reinoso, Suardi, Nazareno, Gómez-Sancha, Fernando

“…Purpose HoLEP represents an excellent treatment option for benign prostatic hyperplasia. Recently, ‘en bloc’ techniques resulting in improved visualization,…”
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Conservation of Protein Structure over Four Billion Years by Ingles-Prieto, Alvaro, Ibarra-Molero, Beatriz, Delgado-Delgado, Asuncion, Perez-Jimenez, Raul, Fernandez, Julio M., Gaucher, Eric A., Sanchez-Ruiz, Jose M., Gavira, Jose A.

“…Little is known about the evolution of protein structures and the degree of protein structure conservation over planetary time scales. Here, we report the…”
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Analysis of Irreversible Thermodynamic Losses in Emissive-Energy Harvesters Based on Photon Beams by Fernandez, Julio Juan

“…An analysis of irreversible energy losses that happen upon emissive-energy conversion is presented in this article. For this, we show that in these converters,…”
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Protein folding modulates the chemical reactivity of a Gram-positive adhesin by Alonso-Caballero, Alvaro, Echelman, Daniel J., Tapia-Rojo, Rafael, Haldar, Shubhasis, Eckels, Edward C., Fernandez, Julio M.

“…Gram-positive bacteria colonize mucosal tissues, withstanding large mechanical perturbations such as coughing, which generate shear forces that exceed the…”
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Force-Clamp Spectroscopy Monitors the Folding Trajectory of a Single Protein by Fernandez, Julio M., Li, Hongbin

“…We used force-clamp atomic force micoscopy to measure the end-to-end length of the small protein ubiquitin during its folding reaction at the single-molecule…”
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Direct observation of a coil-to-helix contraction triggered by vinculin binding to talin by Tapia-Rojo, Rafael, Alonso-Caballero, Alvaro, Fernandez, Julio M

“…Vinculin binds unfolded talin domains in focal adhesions, which recruits actin filaments to reinforce the mechanical coupling of this organelle. However, it…”
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