Search Results - "Fernandez, Juliette"
-
1
Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration
Published in PloS one (25-09-2012)“…The nuclear pore complex (NPC) mediates nucleo-cytoplasmic transport of macromolecules and is an obligatory point of passage and functional bottleneck in the…”
Get full text
Journal Article -
2
Transportin-1 binds to the HIV-1 capsid via a nuclear localization signal and triggers uncoating
Published in Nature microbiology (01-11-2019)“…The initial steps of HIV replication in host cells prime the virus for passage through the nuclear pore and drive the establishment of a productive and…”
Get full text
Journal Article -
3
Daxx Inhibits HIV-1 Reverse Transcription and Uncoating in a SUMO-Dependent Manner
Published in Viruses (11-06-2020)“…Death domain-associated protein 6 (Daxx) is a multifunctional, ubiquitously expressed and highly conserved chaperone protein involved in numerous cellular…”
Get full text
Journal Article -
4
Spinal cord injury dysregulates fibro-adipogenic progenitors miRNAs signaling to promote neurogenic heterotopic ossifications
Published in Communications biology (12-09-2023)“…Neurogenic heterotopic ossifications are intramuscular bone formations developing following central nervous system injury. The pathophysiology is poorly…”
Get full text
Journal Article -
5
Endogenous TRIM5α Function Is Regulated by SUMOylation and Nuclear Sequestration for Efficient Innate Sensing in Dendritic Cells
Published in Cell reports (Cambridge) (12-01-2016)“…During retroviral infection, viral capsids are subject to restriction by the cellular factor TRIM5α. Here, we show that dendritic cells (DCs) derived from…”
Get full text
Journal Article -
6
Cross-species amplification of 41 microsatellites in European cyprinids: A tool for evolutionary, population genetics and hybridization studies
Published in BMC research notes (17-05-2010)“…Cyprinids display the most abundant and widespread species among the European freshwater Teleostei and are known to hybridize quite commonly. Nevertheless, a…”
Get full text
Journal Article -
7
Residual HIV-1 DNA Flap-independent nuclear import of cPPT/CTS double mutant viruses does not support spreading infection
Published in Retrovirology (10-11-2011)“…The human immunodeficiency virus type 1 (HIV-1) central DNA Flap is generated during reverse transcription as a result of (+) strand initiation at the central…”
Get full text
Journal Article -
8
Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses
Published in Cell chemical biology (21-07-2022)“…The increasingly frequent outbreaks of pathogenic viruses have underlined the urgent need to improve our arsenal of antivirals that can be deployed for future…”
Get more information
Journal Article -
9
Measuring the subcellular compartmentalization of viral infections by protein complementation assay
Published in Proceedings of the National Academy of Sciences - PNAS (12-01-2021)“…The recent emergence and reemergence of viruses in the human population has highlighted the need to develop broader panels of therapeutic molecules…”
Get full text
Journal Article -
10
Microtubule-associated Proteins 1 (MAP1) Promote Human Immunodeficiency Virus Type I (HIV-1) Intracytoplasmic Routing to the Nucleus
Published in The Journal of biological chemistry (20-02-2015)“…After cell entry, HIV undergoes rapid transport toward the nucleus using microtubules and microfilaments. Neither the cellular cytoplasmic components nor the…”
Get full text
Journal Article -
11
HIV capsid and productive infection: taking steps in the right direction
Published in Virologie (Montrouge, France) (01-04-2020)“…The Human Immunodeficiency Virus Type-1, the causative agent of AIDS, reaches its site of replication by trafficking through the cytoplasm towards the nucleus,…”
Get full text
Journal Article -
12
Capside du VIH et infection productive : comment arriver à bon pore ?
Published in Virologie (Montrouge, France) (01-04-2020)“…Le virus de l'immunodéficience humaine de type 1, agent causal du sida, a la particularité de pouvoir infecter des cellules qui ne se divisent pas ou peu, en…”
Get full text
Journal Article -
13
HIV capsid and productive infection: taking steps in the right direction
Published in Virologie (Montrouge, France) (01-04-2020)Get full text
Journal Article -
14
RanBP2 regulates the anti-retroviral activity of TRIM5α by SUMOylation at a predicted phosphorylated SUMOylation motif
Published in Communications biology (01-01-2018)“…TRIM5α is a cytoplasmic restriction factor that blocks post-entry retroviral infection. Evidence suggests that its antiviral activity can be regulated by SUMO,…”
Get full text
Journal Article -
15
Correction: Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration
Published in PloS one (19-12-2013)“…Thomas Fricke (TF) was also supported by National Institutes of Health grant R01 AI087390. (2013) Correction: Human Nucleoporins Promote HIV-1 Docking at the…”
Get full text
Journal Article -
16
SUMO regulates the capacity of TRIM5α to inhibit HIV-1
Published in M.S. Médecine sciences (01-02-2019)Get more information
Journal Article -
17
HIV-1 capsid interacts with cytoskeletal-associated proteins for intracytoplasmic routing to the nucleus
Published in Retrovirology (19-09-2013)“…Doc number: P34…”
Get full text
Journal Article -
18
Cross-species amplification of 41 microsatellites in European cyprinids: a tool for evolutionary,population genetics and hybridization studies
Published in BMC research notes (2010)“…Background:Cyprinids display the most abundant and widespread species among the European freshwater Teleostei and are known to hybridize quite commonly…”
Get full text
Journal Article -
19
Correction: Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration
Published in PloS one (01-01-2013)Get full text
Journal Article