Search Results - "Fernandes, Tamiles Caroline Pedrosa"
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The β-blocker carvedilol and the benznidazole modulate the cardiac immune response in the acute infection induced by Colombian strain of the Trypanosoma cruzi
Published in Memórias do Instituto Oswaldo Cruz (18-10-2018)“…BACKGROUND The infection led by Trypanosoma cruzi persists in mammalian tissues causing an inflammatory imbalance. Carvedilol (Cv), a non-selective beta…”
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Insights into IL-33 on inflammatory response during in vitro infection by Trypanosoma cruzi
Published in Immunobiology (1979) (01-07-2022)Get full text
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Screening of synthetic 1,2,3-triazolic compounds inspired by SRPIN340 as anti-Trypanosoma cruzi agents
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2024)“…The current treatments for Chagas disease (CD) include benznidazole and nifurtimox, which have limited efficacy and cause numerous side effects. Triazoles are…”
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Novel Diamides Inspired By Protein Kinase Inhibitors As Anti- Trypanosoma Cruzi Agents: In Vitro and In Vivo Evaluations
Published in Future medicinal chemistry (01-08-2023)Get full text
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Lychnopholide loaded in surface modified polylactide nanocapsules (LYC-PLA-PEG-NC) cure mice infected by Trypanosoma cruzi strain a prototype of resistance to benznidazole and nifurtimox: First insights of its mechanism of action
Published in Experimental parasitology (01-12-2023)“…Chagas disease (CD) remains neglected and causes high morbidity and mortality. The great difficulty is the lack of effective treatment. The current drugs cause…”
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