Search Results - "Fernandes, Pearl Z."

A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation by Cartmell, Alan, Muñoz-Muñoz, Jose, Briggs, Jonathon A., Ndeh, Didier A., Lowe, Elisabeth C., Baslé, Arnaud, Terrapon, Nicolas, Stott, Katherine, Heunis, Tiaan, Gray, Joe, Yu, Li, Dupree, Paul, Fernandes, Pearl Z., Shah, Sayali, Williams, Spencer J., Labourel, Aurore, Trost, Matthias, Henrissat, Bernard, Gilbert, Harry J.

“…Glycans are major nutrients for the human gut microbiota (HGM). Arabinogalactan proteins (AGPs) comprise a heterogenous group of plant glycans in which a…”
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Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target by Sobala, Łukasz F., Fernandes, Pearl Z., Hakki, Zalihe, Thompson, Andrew J., Howe, Jonathon D., Hill, Michelle, Zitzmann, Nicole, Davies, Scott, Stamataki, Zania, Butters, Terry D., Alonzi, Dominic S., Williams, Spencer J., Davies, Gideon J.

“…Mammalian protein N-linked glycosylation is critical for glycoprotein folding, quality control, trafficking, recognition, and function. N-linked glycans are…”
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Computational Design of Experiment Unveils the Conformational Reaction Coordinate of GH125 α‑Mannosidases by Alonso-Gil, Santiago, Males, Alexandra, Fernandes, Pearl Z, Williams, Spencer J, Davies, Gideon J, Rovira, Carme

“…Conformational analysis of enzyme-catalyzed mannoside hydrolysis has revealed two predominant conformational itineraries through B 2,5 or 3 H 4…”
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Exploration of Strategies for Mechanism‐Based Inhibitor Design for Family GH99 endo‐α‐1,2‐Mannanases by Fernandes, Pearl Z., Petricevic, Marija, Sobala, Lukasz, Davies, Gideon J., Williams, Spencer J.

“…endo‐α‐1,2‐Mannosidases and ‐mannanases, members of glycoside hydrolase family 99 (GH99), cleave α‐Glc/Man‐1,3‐α‐Man‐OR structures within mammalian N‐linked…”
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Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-α-1,2-Mannanase by Petricevic, Marija, Sobala, Lukasz F, Fernandes, Pearl Z, Raich, Lluís, Thompson, Andrew J, Bernardo-Seisdedos, Ganeko, Millet, Oscar, Zhu, Sha, Sollogoub, Matthieu, Jiménez-Barbero, Jesús, Rovira, Carme, Davies, Gideon J, Williams, Spencer J

“…Inhibitor design incorporating features of the reaction coordinate and transition-state structure has emerged as a powerful approach for the development of…”
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Author Correction: A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation by Cartmell, Alan, Muñoz-Muñoz, Jose, Briggs, Jonathon A., Ndeh, Didier A., Lowe, Elisabeth C., Baslé, Arnaud, Terrapon, Nicolas, Stott, Katherine, Heunis, Tiaan, Gray, Joe, Yu, Li, Dupree, Paul, Fernandes, Pearl Z., Shah, Sayali, Williams, Spencer J., Labourel, Aurore, Trost, Matthias, Henrissat, Bernard, Gilbert, Harry J.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Contribution of Shape and Charge to the Inhibition of a Family GH99 \textitendo -α-1,2-Mannanase by Petricevic, Marija, Sobala, Lukasz F., Fernandes, Pearl Z., Raich, Lluís, Thompson, Andrew J., Bernardo-Seisdedos, Ganeko, Millet, Oscar, Zhu, Sha, Sollogoub, Matthieu, Jiménez-Barbero, Jesús, Rovira, Carme, Davies, Gideon J., Williams, Spencer J.

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Engineering a surface endogalactanase into Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation by Cartmell, Alan, Muñoz-Muñoz, Jose, Briggs, Jonathon, Ndeh, Didier A., Lowe, Elisabeth C., Baslé, Arnaud, Terrapon, Nicolas, Stott, Katherine, Heunis, Tiaan, Gray, Joe, Yu, Li, Dupree, Paul, Fernandes, Pearl Z., Shah, Sayali, Williams, Spencer J., Labourel, Aurore, Trost, Matthias, Henrissat, Bernard, Gilbert, Harry J.

“…Glycans are major nutrients for the human gut microbiota (HGM). Arabinogalactan proteins (AGPs) comprise a heterogenous group of plant glycans in which a…”
Get full text