Search Results - "Fernández, Elena"
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Biopolymer-Based Nanoparticles for Cystic Fibrosis Lung Gene Therapy Studies
Published in Materials (13-01-2018)“…Lung gene therapy for cystic fibrosis disease has not been successful due to several challenges such as the absence of an appropriate vector. Therefore,…”
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Biocatalytic Oxidation Reactions: A Chemist's Perspective
Published in Angewandte Chemie International Edition (20-07-2018)“…Oxidation chemistry using enzymes is approaching maturity and practical applicability in organic synthesis. Oxidoreductases (enzymes catalysing redox…”
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Gut microbiota and the polycystic ovary syndrome (PCOS): influence of sex, sex hormones and obesity
Published in The journal of clinical endocrinology and metabolism (01-07-2018)“…Gut microbiota play a major role in health and disease by influencing physiology, metabolism, nutrition, and immune function. To evaluate the composition of…”
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Selective Activation of C−H Bonds in a Cascade Process Combining Photochemistry and Biocatalysis
Published in Angewandte Chemie International Edition (27-11-2017)“…Selective oxyfunctionalizations of inert C−H bonds can be achieved under mild conditions by using peroxygenases. This approach, however, suffers from the poor…”
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5
Mediterranean diet and cardiodiabesity: a review
Published in Nutrients (04-09-2014)“…Cardiodiabesity has been used to define and describe the well-known relationship between type 2 Diabetes Mellitus (T2DM), obesity, the metabolic syndrome…”
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Amplified Detection of Breast Cancer Autoantibodies Using MUC1-Based Tn Antigen Mimics
Published in Journal of medicinal chemistry (13-08-2020)“…In many human carcinomas, mucin-1 (MUC1) is overexpressed and aberrantly glycosylated, resulting in the exposure of previously hidden antigens. This generates…”
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Speeding-up the Determination of Protein–Ligand Affinities by STD NMR: The Reduced Data Set STD NMR Approach (rd-STD NMR)
Published in Analytical chemistry (Washington) (16-01-2024)“…STD NMR spectroscopy is a powerful ligand-observed NMR tool for screening and characterizing the interactions of small molecules and low molecular weight…”
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Intensive care nurses' experiences during the COVID‐19 pandemic: A qualitative study
Published in Nursing in critical care (01-09-2021)“…Background Because of the COVID‐19 pandemic, health care systems worldwide are working under challenging conditions. Patients, who are seriously ill, require…”
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Influence of Environmental Conditions in the Storage Systems for the Conservation of Macrovertebrate Fossils
Published in International journal of conservation science (01-04-2023)“…The macrovertebrate fossil collections are one of the most important tools for studying past ecosystems. However, the conservation of the fossil material is…”
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10
Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases
Published in Chemical communications (Cambridge, England) (25-04-2016)“…Lysosomal storage disorders (LSDs) are often caused by mutations that destabilize native folding and impair the trafficking of enzymes, leading to premature…”
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Cardiopulmonary resuscitation by law enforcement agents in Spain: lessons from a mixed methods case study
Published in Emergency Care Journal (23-06-2023)“…Much of the law enforcement work takes place close to the public, often arriving at the scene before medical services in the case of victims of out-of-hospital…”
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12
TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury
Published in British journal of pharmacology (01-09-2021)“…Background and Purpose Activation of astrocytes contributes to synaptic remodelling, tissue repair and neuronal survival following traumatic brain injury…”
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13
Prediction of acute myeloid leukaemia risk in healthy individuals
Published in Nature (London) (01-07-2018)“…The incidence of acute myeloid leukaemia (AML) increases with age and mortality exceeds 90% when diagnosed after age 65. Most cases arise without any…”
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Relationships among general health, job satisfaction, work engagement and job features in nurses working in a public hospital: A cross‐sectional study
Published in Journal of clinical nursing (01-04-2019)“…Aim and objective To describe relations among health, job satisfaction, work engagement and job features in Spanish nurses working in a public hospital…”
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15
Modern Ionospheric Ray Tracer for Earth Observation Satellite Missions
Published in IEEE journal of selected topics in applied earth observations and remote sensing (2024)“…Electromagnetic waves propagation through the ionosphere is subject to several effects including refraction, absorption, signal delay, or Faraday rotation. A…”
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Modulation of microglia polarization dynamics during diabetic retinopathy in db/db mice
Published in Biochimica et biophysica acta (01-09-2016)“…Retinal diseases linked to inflammation are often accompanied by macrophage/microglial cells activation. However, the dynamics between M1 (pro-inflammatory)…”
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The innovation antecedents behind the servitization–performance relationship
Published in R & D management (01-06-2023)“…Servitization allows manufacturing firms to differentiate themselves from rivals and become more competitive. Scholars have studied the service paradox, but…”
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Short‐term effects of hyaluronic acid on the subgingival microbiome in peri‐implantitis: A randomized controlled clinical trial
Published in Journal of periodontology (1970) (01-06-2020)“…Background The aim of our study was to evaluate the effects of a hyaluronic acid (HA) gel at 45 days on the microbiome of implants with peri‐implantitis with…”
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Expanding the Spectrum of Light-Driven Peroxygenase Reactions
Published in ACS catalysis (01-02-2019)“…Peroxygenases require a controlled supply of H2O2 to operate efficiently. Here, we propose a photocatalytic system for the reductive activation of ambient O2…”
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Stereoselective Synthesis of Iminosugar 2‑Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis
Published in Journal of organic chemistry (03-04-2020)“…The first examples of iminosugar-type 2-deoxy(thio)glycoside mimetics are reported. The key step is the activation of a bicyclic iminoglycal carbamate to…”
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