Search Results - "Fernø, J"

Gastric GDF15 levels are regulated by age, sex, and nutritional status in rodents and humans by Pena-Leon, V., Perez-Lois, R., Villalon, M., Folgueira, C., Barja-Fernández, S., Prida, E., Baltar, J., Santos, F., Fernø, J., García-Caballero, T., Nogueiras, R., Quiñones, M., Al-Massadi, O., Seoane, L. M.

“…Aim Growth differentiation factor 15 (GDF15) is a stress response cytokine that has been proposed as a relevant metabolic hormone. Descriptive studies have…”
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Olanzapine depot exposure in male rats: Dose-dependent lipogenic effects without concomitant weight gain by Fernø, J, Ersland, K.M, Duus, I.H, González-García, I, Fossan, K.O, Berge, R.K, Steen, V.M, Skrede, S

“…Abstract Treatment with second-generation antipsychotic agents such as olanzapine frequently results in metabolic adverse effects, e.g. hyperphagia, weight…”
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Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples by Le Hellard, S, Mühleisen, T W, Djurovic, S, Fernø, J, Ouriaghi, Z, Mattheisen, M, Vasilescu, C, Raeder, M B, Hansen, T, Strohmaier, J, Georgi, A, Brockschmidt, F F, Melle, I, Nenadic, I, Sauer, H, Rietschel, M, Nöthen, M M, Werge, T, Andreassen, O A, Cichon, S, Steen, V M

“…Several studies have reported structural brain abnormalities, decreased myelination and oligodendrocyte dysfunction in schizophrenia. In the central nervous…”
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Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia by Jassim, G, Fernø, J, Theisen, F M, Haberhausen, M, Christoforou, A, Håvik, B, Gebhardt, S, Remschmidt, H, Mehler-Wex, C, Hebebrand, J, Lehellard, S, Steen, V M

“…Marked inter-individual variation has been observed with respect to the risk of weight gain and related metabolic disturbances during antipsychotic treatment,…”
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Hypothalamic mTOR: the rookie energy sensor by Martínez de Morentin, P B, Martinez-Sanchez, N, Roa, J, Ferno, J, Nogueiras, R, Tena-Sempere, M, Dieguez, C, Lopez, M

“…Optimal cellular function and therefore organism's survival is determined by the sensitive and accurate convergence of energy and nutrient abundance to cell…”
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Association between the insulin-induced gene 2 ( ) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects? by Le Hellard, S, Theisen, F M, Haberhausen, M, Raeder, M B, Fernø, J, Gebhardt, S, Hinney, A, Remschmidt, H, Krieg, J C, Mehler-Wex, C, Nöthen, M M, Hebebrand, J, Steen, V M

“…Atypical antipsychotics are nowadays the most widely used drugs to treat schizophrenia and other psychosis. Unfortunately, some of them can cause major…”
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Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action? by Fernø, J, Raeder, M B, Vik-Mo, A O, Skrede, S, Glambek, M, Tronstad, K-J, Breilid, H, Løvlie, R, Berge, R K, Stansberg, C, Steen, V M

“…Several studies have reported on structural abnormalities, decreased myelination and oligodendrocyte dysfunction in post-mortem brains from schizophrenic…”
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Increased inflammatory proteins in patients with severe obesity is associated with persistent myocardial dysfunction one year after bariatric surgery. The FatWest study by Grymyr, L M, Mellgren, G, Meyer, K, Gerdts, E, Nadirpour, S, Ferno, J, Nedrebo, B, Cramariuc, D

“…Abstract Background Over half of patients with severe obesity have subclinical cardiac dysfunction and about 40% maintain impaired left ventricular (LV)…”
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Differential effects of antipsychotic drugs on ATP-binding cassette type A1 (ABCA1) and apolipoprotein E (ApoE) gene expression in cultured cells by Vik-Mo, A O, Fernø, J, Steen, V M

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Single-cell analyses of transcriptional heterogeneity during drug tolerance transition in cancer cells by RNA sequencing by Lee, Mei-Chong Wendy, Lopez-Diaz, Fernando J, Khan, Shahid Yar, Tariq, Muhammad Akram, Dayn, Yelena, Vaske, Charles Joseph, Radenbaugh, Amie J, Kim, Hyunsung John, Emerson, Beverly M, Pourmand, Nader

“…The acute cellular response to stress generates a subpopulation of reversibly stress-tolerant cells under conditions that are lethal to the majority of the…”
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Differential effects of acute clozapine exposure on the expression of lipid biosynthesis genes in rat liver by Fernø, J, Vik-Mo, A O, Jassim, G, Steen, V M

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Natural Killer Cells as Sensors of Adipose Tissue Stress by Fernø, Johan, Strand, Kristina, Mellgren, Gunnar, Stiglund, Natalie, Björkström, Niklas K.

“…Adipose tissue macrophages (ATMs) orchestrate low-grade chronic adipose tissue inflammation, linking obesity and insulin resistance. Whereas factors…”
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Metabolic actions of the growth hormone-insulin growth factor-1 axis and its interaction with the central nervous system by Al-Massadi, Omar, Parini, Paolo, Fernø, Johan, Luquet, Serge, Quiñones, Mar

“…The growth hormone/insulin growth factor-1 axis is a key endocrine system that exerts profound effects on metabolism by its actions on different peripheral…”
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Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients by Vik-Mo, A O, Birkeneas, A B, Fernø, J, Jonsdottir, H, Andreassen, O A, Steen, V M

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Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress by González-García, Ismael, Contreras, Cristina, Estévez-Salguero, Ánxela, Ruíz-Pino, Francisco, Colsh, Benoit, Pensado, Iván, Liñares-Pose, Laura, Rial-Pensado, Eva, Martínez de Morentin, Pablo B., Fernø, Johan, Diéguez, Carlos, Nogueiras, Rubén, Le Stunff, Hervé, Magnan, Christophe, Tena-Sempere, Manuel, López, Miguel

“…Compelling evidence has shown that, besides its putative effect on the regulation of the gonadal axis, estradiol (E2) exerts a dichotomic effect on the…”
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Distinct T cell subsets in adipose tissue are associated with obesity by Haugstøyl, Martha E., Cornillet, Martin, Strand, Kristina, Stiglund, Natalie, Sun, Dan, Lawrence‐Archer, Laurence, Hjellestad, Iren D., Sparrelid, Ernesto, Busch, Christian, Hjelmesæth, Jøran, Hertel, Jens K., Ponzetta, Andrea, Mellgren, Gunnar, Fernø, Johan, Björkström, Niklas K.

“…Adipose tissue inflammation is a driving factor for the development of obesity‐associated metabolic disturbances, and a role of adipose tissue T cells in…”
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Retained NK Cell Phenotype and Functionality in Non-alcoholic Fatty Liver Disease by Stiglund, Natalie, Strand, Kristina, Cornillet, Martin, Stål, Per, Thorell, Anders, Zimmer, Christine L, Näslund, Erik, Karlgren, Silja, Nilsson, Henrik, Mellgren, Gunnar, Fernø, Johan, Hagström, Hannes, Björkström, Niklas K

“…Non-alcoholic fatty liver disease (NAFLD), and the progressive stage non-alcoholic steatohepatitis (NASH), is the predominant cause of chronic liver disease…”
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Role of the Neutral Amino Acid Transporter SLC7A10 in Adipocyte Lipid Storage, Obesity, and Insulin Resistance by Jersin, Regine Å, Tallapragada, Divya Sri Priyanka, Madsen, André, Skartveit, Linn, Fjære, Even, McCann, Adrian, Lawrence-Archer, Laurence, Willems, Aron, Bjune, Jan-Inge, Bjune, Mona S, Våge, Villy, Nielsen, Hans Jørgen, Thorsen, Håvard Luong, Nedrebø, Bjørn Gunnar, Busch, Christian, Steen, Vidar M, Blüher, Matthias, Jacobson, Peter, Svensson, Per-Arne, Fernø, Johan, Rydén, Mikael, Arner, Peter, Nygård, Ottar, Claussnitzer, Melina, Ellingsen, Ståle, Madsen, Lise, Sagen, Jørn V, Mellgren, Gunnar, Dankel, Simon N

“…Elucidation of mechanisms that govern lipid storage, oxidative stress, and insulin resistance may lead to improved therapeutic options for type 2 diabetes and…”
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Phenotypic diversity of human adipose tissue-resident NK cells in obesity by Haugstøyl, Martha E, Cornillet, Martin, Strand, Kristina, Stiglund, Natalie, Sun, Dan, Lawrence-Archer, Laurence, Hjellestad, Iren D, Busch, Christian, Mellgren, Gunnar, Björkström, Niklas K, Fernø, Johan

“…Natural killer (NK) cells have emerged as key mediators of obesity-related adipose tissue inflammation. However, the phenotype of NK cell subsets residing in…”
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Characterisation of natural killer cell subsets in adipose tissue of morbidly obese subjects associated with type 2 diabetes by Haugstoyl, ME, Cornillet, M, Stiglund, N, Strand, K, Mellgren, G, Bjorkstrom, N, Ferno, J

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