Search Results - "Fernández Grecco, Horacio"

Ibrutinib impairs the phagocytosis of rituximab-coated leukemic cells from chronic lymphocytic leukemia patients by human macrophages by Borge, Mercedes, Belén Almejún, María, Podaza, Enrique, Colado, Ana, Fernández Grecco, Horacio, Cabrejo, María, Bezares, Raimundo F, Giordano, Mirta, Gamberale, Romina

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In Vitro Sensitivity to Venetoclax and Microenvironment Protection in Hairy Cell Leukemia by Vereertbrugghen, Alexia, Colado, Ana, Gargiulo, Ernesto, Bezares, Raimundo Fernando, Fernández Grecco, Horacio, Cordini, Gregorio, Custidiano, Maria del Rosario, François, Jean-Hugues, Berchem, Guy, Borge, Mercedes, Paggetti, Jerome, Moussay, Etienne, Gamberale, Romina, Giordano, Mirta, Morande, Pablo Elías

“…Current standard treatment of patients with hairy cell leukemia (HCL), a chronic B-cell neoplasia of low incidence that affects the elderly, is based on the…”
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The expression of sphingosine-1 phosphate receptor-1 in chronic lymphocytic leukemia cells is impaired by tumor microenvironmental signals and enhanced by piceatannol and R406 by Borge, Mercedes, Remes Lenicov, Federico, Nannini, Paula R, de los Ríos Alicandú, María M, Podaza, Enrique, Ceballos, Ana, Fernández Grecco, Horacio, Cabrejo, María, Bezares, Raimundo F, Morande, Pablo E, Oppezzo, Pablo, Giordano, Mirta, Gamberale, Romina

“…Chronic lymphocytic leukemia (CLL) is characterized by the progressive accumulation of clonal B lymphocytes. Proliferation occurs in lymphoid tissues upon…”
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Expression and function of cathelicidin hCAP18/LL-37 in chronic lymphocytic leukemia by Podaza, Enrique, Palacios, Florencia, Croci, Diego O, Risnik, Denise, Yan, Xiao J, Almejún, María Belén, Colado, Ana, Elías, Esteban E, Borge, Mercedes, Morande, Pablo E, Bezares, Raimundo, Fernández-Grecco, Horacio, Rabinovich, Gabriel A, Gamberale, Romina, Chiorazzi, Nicholas, Giordano, Mirta

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Immunoregulatory effects of Lurbinectedin in chronic lymphocytic leukemia by Risnik, Denise, Colado, Ana, Podaza, Enrique, Almejún, María Belén, Elías, Esteban Enrique, Bezares, Raimundo Fernando, Fernández-Grecco, Horacio, Seija, Noé, Oppezzo, Pablo, Borge, Mercedes, Gamberale, Romina, Giordano, Mirta

“…Despite significant therapeutic improvements chronic lymphocytic leukemia (CLL) remains an incurable disease and there is a persistent pursuit of new treatment…”
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Autologous T-cell activation fosters ABT-199 resistance in chronic lymphocytic leukemia: rationale for a combined therapy with SYK inhibitors and anti-CD20 monoclonal antibodies by Elías, Esteban Enrique, Almejún, María Belén, Colado, Ana, Cordini, Gregorio, Vergara-Rubio, Maricef, Podaza, Enrique, Risnik, Denise, Cabrejo, María, Fernández-Grecco, Horacio, Bezares, Raimundo Fernando, Custidiano, María del Rosario, Sánchez-Ávalos, Julio César, Vicente, Ángeles, Garate, Gonzalo Martín, Borge, Mercedes, Giordano, Mirta, Gamberale, Romina

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Revisiting the role of interleukin-8 in chronic lymphocytic leukemia by Risnik, Denise, Podaza, Enrique, Almejún, María B., Colado, Ana, Elías, Esteban E., Bezares, Raimundo F., Fernández-Grecco, Horacio, Cranco, Santiago, Sánchez-Ávalos, Julio C., Borge, Mercedes, Gamberale, Romina, Giordano, Mirta

“…The proliferation and survival of malignant B cells in chronic lymphocytic leukemia (CLL) depend on signals from the microenvironment in lymphoid tissues…”
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Effect of the BTK inhibitor ibrutinib on macrophage- and γδ T cell-mediated response against Mycobacterium tuberculosis by Colado, Ana, Genoula, Melanie, Cougoule, Céline, Marín Franco, José L., Almejún, María B., Risnik, Denise, Kviatcovsky, Denise, Podaza, Enrique, Elías, Esteban E., Fuentes, Federico, Maridonneau-Parini, Isabelle, Bezares, Fernando R., Fernandez Grecco, Horacio, Cabrejo, María, Jancic, Carolina, Sasiain, María del Carmen, Giordano, Mirta, Gamberale, Romina, Balboa, Luciana, Borge, Mercedes

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Sphingosine kinase 1 participates in the activation, proliferation and survival of chronic lymphocytic leukemia cells by Almejún, María Belén, Borge, Mercedes, Colado, Ana, Elías, Esteban Enrique, Podaza, Enrique, Risnik, Denise, De Brasi, Carlos Daniel, Stanganelli, Carmen, Slavutsky, Irma, Cabrejo, María, Fernández-Grecco, Horacio, Bezares, Raimundo Fernando, Cranco, Santiago, Burgos, Rubén Ángel, Sánchez-Ávalos, Julio César, Oppezzo, Pablo, Giordano, Mirta, Gamberale, Romina

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Neutrophils from chronic lymphocytic leukemia patients exhibit an increased capacity to release extracellular traps (NETs) by Podaza, Enrique, Sabbione, Florencia, Risnik, Denise, Borge, Mercedes, Almejún, María B., Colado, Ana, Fernández-Grecco, Horacio, Cabrejo, María, Bezares, Raimundo F., Trevani, Analía, Gamberale, Romina, Giordano, Mirta

“…Chronic lymphocytic leukemia (CLL) is characterized by immune defects that contribute to a high rate of infections and autoimmune cytopenias. Neutrophils are…”
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Venetoclax-resistant CLL cells show a highly activated and proliferative phenotype by Elias, Esteban Enrique, Sarapura Martinez, Valeria Judith, Amondarain, Mikele, Colado, Ana, Cordini, Gregorio, Bezares, Raimundo Fernando, Fernandez Grecco, Horacio, Custidiano, Maria del Rosario, Sánchez Ávalos, Julio César, Garate, Gonzalo, Pavlovsky, Miguel A., Borge, Mercedes, Giordano, Mirta, Gamberale, Romina

“…Venetoclax treatment has demonstrated efficacy and a safety profile in chronic lymphocytic leukemia (CLL) patients, however the emergence of resistant cells is…”
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Second generation BTK inhibitors impair the anti‐fungal response of macrophages and neutrophils by Colado, Ana, Marín Franco, José L., Elías, Esteban E., Amondarain, Mikele, Vergara Rubio, Maricef, Sarapura Martínez, Valeria, Cordini, Gregorio, Fuentes, Federico, Balboa, Luciana, Fernandez Grecco, Horacio, Pavlovsky, Miguel, Bezares, Fernando, Morande, Pablo, Giordano, Mirta, Gamberale, Romina, Borge, Mercedes

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Chronic lymphocytic leukemia cells increase neutrophils survival and promote their differentiation into CD16highCD62Ldim immunosuppressive subset by Podaza, Enrique, Risnik, Denise, Colado, Ana, Elías, Esteban, Almejún, María Belén, Fernandez Grecco, Horacio, Bezares, Raimundo Fernando, Borge, Mercedes, Gamberale, Romina, Giordano, Mirta

“…Reprogramming of neutrophils by malignant cells is well‐described for many types of solid tumors, but data remain scarce for hematological diseases. Chronic…”
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Expression and function of cathelicidin hCAP18/LL-37 in chronic lymphocytic leukemia by Podaza, Enrique, Palacios, Florencia, Croci, Diego O, Risnik, Denise, Yan, Xiao J, Almejún, María Belén, Colado, Ana, Elías, Esteban E, Borge, Mercedes, Morande, Pablo E, Bezares, Raimundo, Fernández-Grecco, Horacio, Rabinovich, Gabriel A, Gamberale, Romina, Chiorazzi, Nicholas, Giordano, Mirta

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The kinase inhibitors R406 and GS-9973 impair T cell functions and macrophage-mediated anti-tumor activity of rituximab in chronic lymphocytic leukemia patients by Colado, Ana, Almejún, María Belén, Podaza, Enrique, Risnik, Denise, Stanganelli, Carmen, Elías, Esteban Enrique, Dos Santos, Patricia, Slavutsky, Irma, Fernández Grecco, Horacio, Cabrejo, María, Bezares, Raimundo Fernando, Giordano, Mirta, Gamberale, Romina, Borge, Mercedes

“…Small molecules targeting kinases involved in B cell receptor signaling are showing encouraging clinical activity in chronic lymphocytic leukemia (CLL)…”
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The effect of ibrutinib on neutrophil and γδ T cell functions by Risnik, Denise, Elías, Esteban E., Keitelman, Irene, Colado, Ana, Podaza, Enrique, Cordini, Gregorio, Vergara Rubio, Maricef, Fernández Grecco, Horacio, Bezares, Raimundo Fernando, Borge, Mercedes, Trevani, Analía, Giordano, Mirta, Jancic, Carolina, Gamberale, Romina

“…Ibrutinib is a BTK/ITK inhibitor with efficacy for the treatment of various lymphoid cancers, including CLL. Considering that innate and adaptative immune…”
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Autologous T cell activation fosters ABT-199 resistance in chronic lymphocytic leukemia: rationale for a combined therapy with SYK inhibitors and anti-CD20 MoAbs by Elías, Esteban Enrique, Almejún, María Belén, Colado, Ana, Cordini, Gregorio, Vergara-Rubio, Maricef, Podaza, Enrique, Risnik, Denise, Cabrejo, María, Fernández-Grecco, Horacio, Bezares, Raimundo Fernando, Custidiano, María Del Rosario, Sánchez-Ávalos, Julio César, Vicente, Ángeles, Garate, Gonzalo Martín, Borge, Mercedes, Giordano, Mirta, Gamberale, Romina

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Chronic lymphocytic leukemia cells increase neutrophils survival and promote their differentiation into CD16 high CD62L dim immunosuppressive subset by Podaza, Enrique, Risnik, Denise, Colado, Ana, Elías, Esteban, Almejún, María Belén, Fernandez Grecco, Horacio, Bezares, Raimundo Fernando, Borge, Mercedes, Gamberale, Romina, Giordano, Mirta

“…Reprogramming of neutrophils by malignant cells is well-described for many types of solid tumors, but data remain scarce for hematological diseases. Chronic…”
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Efficacy of a Short Course of Chemotherapy with ABVD for Elderly Patients with Hodgkin Lymphoma for All Disease Stages by Ciliberti, Esteban, Fernandez, Isolda I., Prates, Maria Virginia, Negri Aranguren, Pedro, Milone, Gustavo, Kurgansky, Nicolas Matias, Zoppegno, Lucia, Sackman, Federico, Cerutti, Ider Ramon, Zabaljauregui, Soledad, Mariano, Romina, Fernandez Grecco, Horacio, Saba, Silvia, Remaggi, Guillermina, Cabrejo, Maria Del Rosario, Rudoy, Silvia, Castano, Vanesa, Roveri, Eriberto Antonio, Taus, Rossana L., Gumpel, Carina, Sakamoto, Juan Francisco, Pavlovsky, Astrid

“…INTRODUCTION Treatment of classical Hodgkin's lymphoma (cHL) in the elderly population remains a challenge. Prevalence of co morbidities, increased toxicity to…”
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Sphingosine Kinases (SK): Key Molecules Associated with the Activation, Proliferation and Ibrutinib-Induced Cell Death of Chronic Lympocytic Leukemia Cells by Almejun, Maria Belen, Borge, Mercedes, Colado, Ana, Podaza, Enrique, Risnik, Denise, De Brasi, Carlos Daniel, Oppezzo, Pablo, Cabrejo, Maria, Fernandez Grecco, Horacio, Bezares, Raimundo F., Cranco, Santiago C, Burgos, Ruben A., Sanchez Avalos, Julio Cesar, Giordano, Mirta N., Gamberale, Romina

“…Leukemic cells from CLL patients can survive and proliferate within lymphoid tissues where the supportive microenvironment favors their accumulation. We have…”
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