Search Results - "Fernández Borges, Natalia"

YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias by Llorens, Franc, Thüne, Katrin, Tahir, Waqas, Kanata, Eirini, Diaz-Lucena, Daniela, Xanthopoulos, Konstantinos, Kovatsi, Eleni, Pleschka, Catharina, Garcia-Esparcia, Paula, Schmitz, Matthias, Ozbay, Duru, Correia, Susana, Correia, Ângela, Milosevic, Ira, Andréoletti, Olivier, Fernández-Borges, Natalia, Vorberg, Ina M, Glatzel, Markus, Sklaviadis, Theodoros, Torres, Juan Maria, Krasemann, Susanne, Sánchez-Valle, Raquel, Ferrer, Isidro, Zerr, Inga

“…YKL-40 (also known as Chitinase 3-like 1) is a glycoprotein produced by inflammatory, cancer and stem cells. Its physiological role is not completely…”
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Prion-Associated Neurodegeneration Causes Both Endoplasmic Reticulum Stress and Proteasome Impairment in a Murine Model of Spontaneous Disease by Otero, Alicia, Betancor, Marina, Eraña, Hasier, Fernández Borges, Natalia, Lucas, José J, Badiola, Juan José, Castilla, Joaquín, Bolea, Rosa

“…Prion diseases are a group of neurodegenerative disorders that can be spontaneous, familial or acquired by infection. The conversion of the prion protein PrP…”
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A molecular switch controls interspecies prion disease transmission in mice by Sigurdson, Christina J, Nilsson, K Peter R, Hornemann, Simone, Manco, Giuseppe, Fernández-Borges, Natalia, Schwarz, Petra, Castilla, Joaquín, Wüthrich, Kurt, Aguzzi, Adriano

“…Transmissible spongiform encephalopathies are lethal neurodegenerative disorders that present with aggregated forms of the cellular prion protein (PrPC), which…”
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Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis by Llorens, Franc, Thüne, Katrin, Martí, Eulàlia, Kanata, Eirini, Dafou, Dimitra, Díaz-Lucena, Daniela, Vivancos, Ana, Shomroni, Orr, Zafar, Saima, Schmitz, Matthias, Michel, Uwe, Fernández-Borges, Natalia, Andréoletti, Olivier, Del Río, José Antonio, Díez, Juana, Fischer, Andre, Bonn, Stefan, Sklaviadis, Theodoros, Torres, Juan Maria, Ferrer, Isidre, Zerr, Inga

“…Increasing evidence indicates that microRNAs (miRNAs) are contributing factors to neurodegeneration. Alterations in miRNA signatures have been reported in…”
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Cofactors influence the biological properties of infectious recombinant prions by Fernández-Borges, Natalia, Di Bari, Michele A., Eraña, Hasier, Sánchez-Martín, Manuel, Pirisinu, Laura, Parra, Beatriz, Elezgarai, Saioa R., Vanni, Ilaria, López-Moreno, Rafael, Vaccari, Gabriele, Venegas, Vanessa, Charco, Jorge M., Gil, David, Harrathi, Chafik, D’Agostino, Claudia, Agrimi, Umberto, Mayoral, Tomás, Requena, Jesús R., Nonno, Romolo, Castilla, Joaquín

“…Prion diseases are caused by a misfolding of the cellular prion protein (PrP) to a pathogenic isoform named PrP Sc . Prions exist as strains, which are…”
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Prion replication without host adaptation during interspecies transmissions by Bian, Jifeng, Khaychuk, Vadim, Angers, Rachel C., Fernández-Borges, Natalia, Vidal, Enric, Meyerett-Reid, Crystal, Kim, Sehun, Calvi, Carla L., Bartz, Jason C., Hoover, Edward A., Agrimi, Umberto, Richt, Jürgen A., Castilla, Joaquín, Telling, Glenn C.

“…Adaptation of prions to new species is thought to reflect the capacity of the host-encoded cellular form of the prion protein (PrPC) to selectively propagate…”
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Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease by Bouybayoune, Ihssane, Mantovani, Susanna, Del Gallo, Federico, Bertani, Ilaria, Restelli, Elena, Comerio, Liliana, Tapella, Laura, Baracchi, Francesca, Fernández-Borges, Natalia, Mangieri, Michela, Bisighini, Cinzia, Beznoussenko, Galina V, Paladini, Alessandra, Balducci, Claudia, Micotti, Edoardo, Forloni, Gianluigi, Castilla, Joaquín, Fiordaliso, Fabio, Tagliavini, Fabrizio, Imeri, Luca, Chiesa, Roberto

“…Fatal familial insomnia (FFI) and a genetic form of Creutzfeldt-Jakob disease (CJD178) are clinically different prion disorders linked to the D178N prion…”
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Rabbits are not resistant to prion infection by Chianini, Francesca, Fernández-Borges, Natalia, Vidal, Enric, Gibbard, Louise, Pintado, Belén, de Castro, Jorge, Priola, Suzette A, Hamilton, Scott, Eaton, Samantha L, Finlayson, Jeanie, Pang, Yvonne, Steele, Philip, Reid, Hugh W, Dagleish, Mark P, Castilla, Joaquín

“…The ability of prions to infect some species and not others is determined by the transmission barrier. This unexplained phenomenon has led to the belief that…”
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Prionemia and Leukocyte-Platelet-Associated Infectivity in Sheep Transmissible Spongiform Encephalopathy Models by LACROUX, Caroline, VILETTE, Didier, WEISBECKER, Jean-Louis, LANTIER, Isabelle, LANTIER, Frederic, SCHELCHER, François, GRASSI, Jacques, CASTILLA, Joaquin, ANDREOLETTI, Olivier, FERNANDEZ-BORGES, Natalia, LITAISE, Claire, LUGAN, Séverine, MOREL, Nathalie, CORBIERE, Fabien, SIMON, Stéphanie, SIMMONS, Hugh, COSTES, Pierrette

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An assessment of the long-term persistence of prion infectivity in aquatic environments by Marín-Moreno, Alba, Espinosa, Juan-Carlos, Fernández-Borges, Natalia, Píquer, Juan, Girones, Rosina, Andreoletti, Olivier, Torres, Juan-María

“…The environment plays a key role in horizontal transmission of prion diseases, since prions are extremely resistant to classical inactivation procedures. In…”
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Recent advances in the development of recombinant vaccines against classical swine fever virus: Cellular responses also play a role in protection by Ganges, Llilianne, Núñez, José I., Sobrino, Francisco, Borrego, Belén, Fernández-Borges, Natalia, Frías-Lepoureau, María T., Rodríguez, Fernando

“…Classical swine fever virus (CSFV) is the causative agent of one of the most devastating porcine haemorrhagic viral diseases, classical swine fever (CSF). CSFV…”
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Animal models for testing anti-prion drugs by Fernández-Borges, Natalia, Elezgarai, Saioa R, Eraña, Hasier, Castilla, Joaquín

“…Prion diseases belong to a group of fatal infectious diseases with no effective therapies available. Throughout the last 35 years, less than 50 different drugs…”
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Infectivity versus Seeding in Neurodegenerative Diseases Sharing a Prion-Like Mechanism by Fernández-Borges, Natalia, Eraña, Hasier, Elezgarai, Saioa R, Harrathi, Chafik, Gayosso, Mayela, Castilla, Joaquín

“…Prions are considered the best example to prove that the biological information can be transferred protein to protein through a conformational change. The term…”
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In vitro studies of the transmission barrier by Fernández-Borges, Natalia, de Castro, Jorge, Castilla, Joaquín

“…Protein misfolding cyclic amplification (PMCA) has proved to be an efficient method mimicking in vitro some of the fundamental steps involved in prion…”
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Dogs are resistant to prion infection, due to the presence of aspartic or glutamic acid at position 163 of their prion protein by Vidal, Enric, Fernández‐Borges, Natalia, Eraña, Hasier, Parra, Beatriz, Pintado, Belén, Sánchez‐Martín, Manuel A., Charco, Jorge M., Ordóñez, Montserrat, Pérez‐Castro, Miguel A., Pumarola, Martí, Mathiason, Candace K., Mayoral, Tomás, Castilla, Joaquín

“…Unlike other species, prion disease has never been described in dogs even though they were similarly exposed to the bovine spongiform encephalopathy (BSE)…”
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Unraveling the key to the resistance of canids to prion diseases by Fernández-Borges, Natalia, Parra, Beatriz, Vidal, Enric, Eraña, Hasier, Sánchez-Martín, Manuel A, de Castro, Jorge, Elezgarai, Saioa R, Pumarola, Martí, Mayoral, Tomás, Castilla, Joaquín

“…One of the characteristics of prions is their ability to infect some species but not others and prion resistant species have been of special interest because…”
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Protective Effect of Val129-PrP against Bovine Spongiform Encephalopathy but not Variant Creutzfeldt-Jakob Disease by Fernandez-Borges, Natalia, Espinosa, Juan Carlos, Marin-Moreno, Alba, Aguilar-Calvo, Patricia, Asante, Emmanuel A, Kitamoto, Tetsuyuki, Mohri, Shirou, Andréoletti, Olivier, Torres, Juan Maria

“…Bovine spongiform encephalopathy (BSE) is the only known zoonotic prion that causes variant Creutzfeldt-Jakob disease (vCJD) in humans. The major risk…”
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Structure of the β2‐α2 loop and interspecies prion transmission by Bett, Cyrus, Fernández‐Borges, Natalia, Kurt, Timothy D., Lucero, Melanie, Nilsson, K. Peter R., Castilla, Joaquín, Sigurdson, Christina J.

“…ABSTRACT Prions are misfolded, aggregated conformers of the prion protein that can be transmitted between species. The precise determinants of interspecies…”
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Canine D163-PrP polymorphic variant does not provide complete protection against prion infection in small ruminant PrP context by Marín-Moreno, Alba, Espinosa, Juan Carlos, Aguilar-Calvo, Patricia, Fernández-Borges, Natalia, Pitarch, José Luis, González, Lorenzo, Torres, Juan María

“…E/D 163 polymorphism of dog prion protein (PrP) has been recently proposed as the variant responsible for canid prion resistance. To further investigate the…”
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Classical BSE dismissed as the cause of CWD in Norwegian red deer despite strain similarities between both prion agents by Marín-Moreno, Alba, Benestad, Sylvie L, Barrio, Tomas, Pirisinu, Laura, Espinosa, Juan Carlos, Tran, Linh, Huor, Alvina, Di Bari, Michele Angelo, Eraña, Hasier, Maddison, Ben C, D'Agostino, Claudia, Fernández-Borges, Natalia, Canoyra, Sara, Jerez-Garrido, Nuria, Castilla, Joaquín, Spiropoulos, John, Bishop, Keith, Gough, Kevin C, Nonno, Romolo, Våge, Jorn, Andréoletti, Olivier, Torres, Juan María

“…The first case of CWD in a Norwegian red deer was detected by a routine ELISA test and confirmed by western blotting and immunohistochemistry in the brain stem…”
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