Search Results - "Fernández‐Mayola, Maday"
-
1
Epidermal growth factor effect on lipopolysaccharide-induced inflammation in fibroblasts derived from diabetic foot ulcer
Published in Scars, burns & healing (01-01-2022)“…Background Diabetic foot ulcers (DFU) are characterised by high levels of inflammatory mediators, resulting from sustained hyperglycaemic insult and the local…”
Get full text
Journal Article -
2
Review: Insulin resistance and mitochondrial dysfunction following severe burn injury
Published in Peptides (New York, N.Y. : 1980) (01-04-2020)“…•Insulin resistance occurs commonly following severe injury.•Mechanisms include increased stress hormones, catecholamines and cytokines.•Serine phosphylation…”
Get full text
Journal Article -
3
Healing enhancement of diabetic wounds by locally infiltrated epidermal growth factor is associated with systemic oxidative stress reduction
Published in International wound journal (01-02-2017)“…The diabetic foot ulcer (DFU) is the leading cause of lower extremity amputation worldwide and is directly associated with comorbidity, disability and…”
Get full text
Journal Article -
4
Intralesional Infiltrations of Arteriosclerotic Tissue Cells-Free Filtrate Reproduce Vascular Pathology in Healthy Recipient Rats
Published in International journal of molecular sciences (28-01-2022)“…Lower-extremity arterial disease is a major health problem with increasing prevalence, often leading to non-traumatic amputation, disability and mortality. The…”
Get full text
Journal Article -
5
Intralesional Infiltrations of Cell-Free Filtrates Derived from Human Diabetic Tissues Delay the Healing Process and Recreate Diabetes Histopathological Changes in Healthy Rats
Published in Frontiers in clinical diabetes and healthcare (online) (26-03-2021)“…Lower limb ulcers in type-2 diabetic patients are a frequent complication that tributes to amputation and reduces survival. We hypothesized that diabetic…”
Get full text
Journal Article -
6
Systemic translation of locally infiltrated epidermal growth factor in diabetic lower extremity wounds
Published in International wound journal (01-12-2019)“…Diabetic foot ulcer is one of the most frightened diabetic complications leading to amputation disability and early mortality. Diabetic wounds exhibit a…”
Get full text
Journal Article -
7
Growth hormone‐releasing peptide 6 prevents cutaneous hypertrophic scarring: early mechanistic data from a proteome study
Published in International wound journal (01-08-2018)“…Hypertrophic scars (HTS) and keloids are forms of aberrant cutaneous healing with excessive extracellular matrix (ECM) deposition. Current therapies still fall…”
Get full text
Journal Article -
8
Burn injury insulin resistance and central nervous system complications: A review
Published in Burns open : an international open access journal for burn injuries (01-04-2020)“…•Stress-related peripheral insulin resistance is a metabolic abnormality that disturbs the ability of tissues to use insulin. It is a difficult to treat…”
Get full text
Journal Article -
9
Cell-Free Filtrates (CFF) as Vectors of a Transmissible Pathologic Tissue Memory Code: A Hypothetical and Narrative Review
Published in International journal of molecular sciences (30-09-2022)“…Cellular memory is a controversial concept representing the ability of cells to "write and memorize" stressful experiences via epigenetic operators. The…”
Get full text
Journal Article -
10
Diabetic Foot Ulcers and Epidermal Growth Factor: Revisiting the Local Delivery Route for a Successful Outcome
Published in BioMed research international (01-01-2017)“…Soon after epidermal growth factor (EGF) discovery, some in vivo models appeared demonstrating its property to enhance cutaneous wound healing. EGF was the…”
Get full text
Journal Article -
11
Growth Hormone-Releasing Peptide 6 Enhances the Healing Process and Improves the Esthetic Outcome of the Wounds
Published in Plastic surgery international (01-01-2016)“…In addition to its cytoprotective effects, growth hormone-releasing peptide 6 (GHRP-6) proved to reduce liver fibrotic induration. CD36 as one of the GHRP-6…”
Get full text
Journal Article -
12
The Potential of Fibroblast Activation Protein-Targeted Imaging as a Biomarker of Cardiac Remodeling and Injury
Published in Current cardiology reports (01-06-2023)“…Purpose of Review Cardiovascular disease features adverse fibrotic processes within the myocardium, leading to contractile dysfunction. Activated cardiac…”
Get full text
Journal Article -
13
Efectos sistémicos del tratamiento intralesional con factor de crecimiento epidérmico (Heberprot-P) en pacientes con úlceras de pie diabético
Published in Anales de la Academia de Ciencias de Cuba (01-01-2022)“…Introducción. La infiltración intralesional con factor de crecimiento epidérmico (EGF) ha emergido como alternativa terapéutica para la cicatrización de las…”
Get full text
Journal Article -
14
GHRP-6, a novel candidate for prevention and treatment of fibrotic disorders
Published in Biotecnología Aplicada (01-06-2017)Get full text
Journal Article -
15
High glucose burden inhibits EGFR/PI3K/AKT1/mTOR signaling pathway in cutaneous fibroblasts
Published in Biotecnología Aplicada“…Diabetic healing failure is the clinical expression of countless molecular and cellular disorders having hyperglycemia as the proximal trigger. The fibroblast…”
Get full text
Journal Article