Search Results - "Fernández‐Clotet, Agnès"
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1
Development and Validation of a Simplified Magnetic Resonance Index of Activity for Crohn’s Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-08-2019)“…The magnetic resonance index of activity (MARIA) for Crohn’s disease (CD) is used to assess the activity of luminal CD. However, it has a number of practical…”
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2
Persistent damage on magnetic resonance enterography in patients with Crohn’s disease in endoscopic remission
Published in Alimentary pharmacology & therapeutics (01-12-2018)“…Summary Background In Crohn's disease, it is essential to distinguish between persistent damage and abnormalities that can heal with anti‐inflammatory therapy…”
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3
Magnetic resonance enterography findings 46 weeks after initiation of biological therapy predict long‐term adverse outcomes in Crohn's disease
Published in Alimentary pharmacology & therapeutics (01-06-2024)“…Summary Background and Aims Magnetic resonance enterography (MRE) depicts transmural changes in response to biological treatment for Crohn's disease (CD);…”
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4
JAK Inhibition: The Most Promising Agents in the IBD Pipeline?
Published in Current pharmaceutical design (01-01-2019)“…Under current therapeutic algorithms, half of the patients with moderate-severe ulcerative colitis or Crohn's disease fail in achieving a sustained remission…”
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Tofacitinib for the treatment of ulcerative colitis
Published in Expert review of clinical immunology (02-11-2018)“…New generations of small molecules are being developed for the treatment of ulcerative colitis. Among them, tofatinib (a Janus kinase (JAK) inhibitor) has…”
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Genetic biomarkers of methotrexate response and safety in Crohn's disease: Data from the Spanish ENEIDA registry
Published in British journal of clinical pharmacology (01-05-2024)“…Aims Methotrexate (MTX) is used to induce and maintain remission in patients with steroid‐dependent Crohn's disease (CD). Despite its proven efficacy, its use…”
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Clinical features, therapeutic requirements and evolution of patients with Crohn’s disease and upper gastrointestinal involvement (CROHNEX study)
Published in Alimentary pharmacology & therapeutics (01-10-2021)“…Summary Background Crohn's disease (CD) with upper gastrointestinal involvement (UGI) may have a more aggressive and refractory course. However, evidence on…”
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Early treatment with anti-tumor necrosis factor agents improves long-term effectiveness in symptomatic stricturing Crohn’s disease
Published in United European gastroenterology journal (01-11-2020)“…Background There is limited evidence on the effectiveness of biological therapy in stricturing complications in patients with Crohn’s disease. Aim The study…”
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9
Fecal Calprotectin for Small Bowel Crohn's Disease: Is It a Cutoff Issue?
Published in Diagnostics (Basel) (01-09-2022)“…(1) Background: Fecal calprotectin (FC) correlates well with colonic inflammatory activity of Crohn’s disease (CD); data about relation of FC and small bowel…”
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10
Controlling leukocyte trafficking in IBD
Published in Pharmacological research (01-09-2020)“…[Display omitted] Inflammatory bowel disease (IBD) is characterized by the accumulation of immune cells, myeloid cells and lymphocytes in the inflamed…”
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11
Pre‐treatment magnetic resonance enterography findings predict the response to TNF‐alpha inhibitors in Crohn's disease
Published in Alimentary pharmacology & therapeutics (01-11-2020)“…Summary Background Identifying predictors of therapeutic response is the cornerstone of personalised medicine. Aim To identify predictors of long‐term healing…”
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12
Ustekinumab and vedolizumab for the prevention of postoperative recurrence of Crohn's disease: Results from the ENEIDA registry
Published in Digestive and liver disease (01-01-2023)“…Anti-TNF agents are the only effective biological agents for the prevention of postoperative recurrence (POR) in Crohn's disease (CD). However, they are…”
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13
Magnetic Resonance Imaging Features Indicative of Permanent Colon Damage in Ulcerative Colitis: An Exploratory Study
Published in Journal of Crohn's and colitis (15-10-2024)“…Abstract Background and Aims It is uncertain whether ulcerative colitis leads to accumulated bowel damage on cross-sectional image. We aimed to characterise…”
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14
De-escalating therapy in inflammatory bowel disease: Results from an observational study in clinical practice
Published in Gastroenterología y hepatología (01-08-2024)“…Combination therapy with an immunomodulator (IMM) and an anti-TNF is commonly recommended in Crohn's disease (CD) and ulcerative colitis (UC) patients…”
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15
Mesenchymal stromal cells in the treatment of perianal fistulas in Crohn's disease
Published in Immunotherapy (01-10-2018)“…Significant unmet needs remain in patients with Crohn's disease and perianal fistulas. Mesenchymal stromal cells have potent immunomodulatory actions. The…”
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16
Clinical Characteristics, Associated Malignancies and Management of Primary Sclerosing Cholangitis in Inflammatory Bowel Disease Patients: A Multicentre Retrospective Cohort Study
Published in Journal of Crohn's and colitis (10-12-2019)“…Abstract Background and Aims Primary sclerosing cholangitis [PSC] is usually associated with inflammatory bowel disease [IBD]. An increased risk of…”
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Adherence to endoscopic surveillance for advanced lesions and colorectal cancer in inflammatory bowel disease: an AEG and GETECCU collaborative cohort study
Published in Alimentary pharmacology & therapeutics (01-06-2022)“…Summary Background and Aims Patients with colonic inflammatory bowel disease (IBD) have a high risk of colorectal cancer (CRC). Current guidelines recommend…”
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18
Tacrolimus induces short‐term but not long‐term clinical response in inflammatory bowel disease
Published in Alimentary pharmacology & therapeutics (01-05-2020)“…Summary Background Tacrolimus is a calcineurin inhibitor commonly used for prophylaxis of rejection in renal and liver transplantation. There are limited but…”
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ADC Values for Detecting Bowel Inflammation and Biologic Therapy Response in Patients With Crohn Disease: A Post Hoc Prospective Trial Analysis
Published in American journal of roentgenology (1976) (01-01-2024)“…New biologic agents for Crohn disease (CD) create a need for noninvasive disease markers. DWI may assess bowel inflammation without contrast agents. The…”
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Real‐world long‐term effectiveness of ustekinumab in Crohn's disease: results from the ENEIDA registry
Published in Alimentary pharmacology & therapeutics (01-09-2020)“…Summary Background Data on the long‐term administration of ustekinumab in recommended doses are limited. Aim To assess the real‐world, long‐term effectiveness…”
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