Search Results - "Fernández, Vicente"
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Expanding the Synthetic Toolbox through Metal–Enzyme Cascade Reactions
Published in Chemical reviews (10-05-2023)“…The combination of metal-, photo-, enzyme-, and/or organocatalysis provides multiple synthetic solutions, especially when the creation of chiral centers is…”
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Unmasking the Hidden Carbonyl Group Using Gold(I) Catalysts and Alcohol Dehydrogenases: Design of a Thermodynamically-Driven Cascade toward Optically Active Halohydrins
Published in ACS catalysis (18-02-2022)“…A concurrent cascade combining the use of a gold(I) N-heterocyclic carbene (NHC) and an alcohol dehydrogenase (ADH) is disclosed for the synthesis of highly…”
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Candida antarctica Lipase B: An Ideal Biocatalyst for the Preparation of Nitrogenated Organic Compounds
Published in Advanced synthesis & catalysis (01-05-2006)“…Candida antarctica lipase B (CAL‐B) is a very effective catalyst for the production of amines and amides using different enzymatic procedures. Simplicity of…”
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Hydrolases in the Stereoselective Synthesis of N-Heterocyclic Amines and Amino Acid Derivatives
Published in Chemical reviews (13-07-2011)“…Busto et al discuss the synthesis of cyclic nitrogenated organic compounds. Among the compounds analyzed are amino acid and amines…”
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Effects of Microbiota Imbalance in Anxiety and Eating Disorders: Probiotics as Novel Therapeutic Approaches
Published in International journal of molecular sciences (26-02-2021)“…Anxiety and eating disorders produce a physiological imbalance that triggers alterations in the abundance and composition of gut microbiota. Moreover, the…”
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Bioavailability of Epigallocatechin Gallate Administered With Different Nutritional Strategies in Healthy Volunteers
Published in Antioxidants (19-05-2020)“…The flavanol epigallocatechin gallate (EGCG) is being tested for the treatment of several diseases in humans. However, its bioavailability and pharmacokinetic…”
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Mimicking Nature: Synthetic Nicotinamide Cofactors for CC Bioreduction Using Enoate Reductases
Published in Organic letters (04-01-2013)“…A series of synthetic nicotinamide cofactors were synthesized to replace natural nicotinamide cofactors and promote enoate reductase (ER) catalyzed reactions…”
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Probiotic Supplementation During the Perinatal and Infant Period: Effects on Gut Dysbiosis and Disease
Published in Nutrients (27-07-2020)“…The perinatal period is crucial to the establishment of lifelong gut microbiota. The abundance and composition of microbiota can be altered by several factors…”
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Synthesis of Optically Active syn- and anti-Chlorohydrins through a Bienzymatic Reductive Cascade
Published in Organic letters (07-10-2022)“…A bienzymatic cascade has been designed and optimized to obtain enantiopure chlorohydrins starting from the corresponding 1-aryl-2-chlorobut-2-en-1-ones. For…”
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The Effects of Vegetarian and Vegan Diet during Pregnancy on the Health of Mothers and Offspring
Published in Nutrients (06-03-2019)“…Vegetarian and vegan diets have increased worldwide in the last decades, according to the knowledge that they might prevent coronary heart disease, cancer, and…”
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Spectrophotometric Assay for the Detection of 2,5-Diformylfuran and Its Validation through Laccase-Mediated Oxidation of 5-Hydroxymethylfurfural
Published in International journal of molecular sciences (01-12-2023)“…Modern biocatalysis requires fast, sensitive, and efficient high-throughput screening methods to screen enzyme libraries in order to seek out novel…”
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Local excision of rectal lesions: Robotic transanal minimally invasive surgery (r‐TAMIS)—A video vignette
Published in Colorectal disease (01-09-2024)Get full text
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Asymmetric Chemoenzymatic Synthesis of Ramatroban Using Lipases and Oxidoreductases
Published in Journal of organic chemistry (18-05-2012)“…A chemoenzymatic asymmetric route for the preparation of enantiopure (R)-ramatroban has been developed for the first time. The action of lipases and…”
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Chemoselective Lipase-Catalyzed Synthesis of Amido Derivatives from 5‑Hydroxymethylfurfurylamine
Published in ACS sustainable chemistry & engineering (17-07-2023)“…The acylations of furfurylamine and 5-hydroxymethylfurfurylamine (HMFA) have been studied finding immobilized Candida antarctica lipase B (CALB) as an ideal…”
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Lipases: Useful biocatalysts for the preparation of pharmaceuticals
Published in Journal of molecular catalysis. B, Enzymatic (01-06-2006)“…Biocatalysis offers a clean and ecological way to perform chemical processes, in mild reaction conditions and with high degree of selectivity. The use of…”
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Robotic minimally invasive abdominal surgery and transanal transection and single‐stapled anastomosis for low rectal cancer—A video vignette
Published in Colorectal disease (01-04-2024)Get full text
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From Diols to Lactones under Aerobic Conditions using a Laccase/TEMPO Catalytic System in Aqueous Medium
Published in Advanced synthesis & catalysis (14-12-2012)“…An efficient catalytic system to oxidize quantitatively aliphatic diols using Trametes versicolor laccase and TEMPO has been developed in aqueous medium…”
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Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis
Published in Proceedings of the National Academy of Sciences - PNAS (10-11-2020)“…The Bcl-2 protein family comprises both pro- and antiapoptotic members that control the permeabilization of the mitochondrial outer membrane, a crucial step in…”
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Analysis of alcohol-metabolizing enzymes genetic variants and RAR/RXR expression in patients diagnosed with fetal alcohol syndrome: a case-control study
Published in BMC genomics (17-06-2024)“…Understanding the mechanisms underlying alcohol metabolism and its regulation, including the effect of polymorphisms in alcohol-metabolizing enzymes, is…”
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