Search Results - "Fernández, Geysson Javier"
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MicroRNA profiling of human primary macrophages exposed to dengue virus identifies miRNA-3614-5p as antiviral and regulator of ADAR1 expression
Published in PLoS neglected tropical diseases (18-10-2017)“…Due to the high burden of dengue disease worldwide, a better understanding of the interactions between dengue virus (DENV) and its human host cells is of the…”
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The expression landscape of cachexia‐inducing factors in human cancers
Published in Journal of cachexia, sarcopenia and muscle (01-08-2020)“…Background Cachexia is a multifactorial syndrome highly associated with specific tumour types, but the causes of variation in cachexia prevalence and severity…”
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Biological sex and age-related differences shape the antiviral response to SARS-CoV-2 infection
Published in Heliyon (01-01-2023)“…For the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, clinical manifestations are broad and highly heterogeneous for both sexes. We…”
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Vitamin D boosts immune response of macrophages through a regulatory network of microRNAs and mRNAs
Published in The Journal of nutritional biochemistry (01-11-2022)“…Vitamin D is associated with the stimulation of innate immunity, inflammation, and host defense against pathogens. Macrophages express receptors of Vitamin D,…”
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Particulate matter impairs immune system function by up-regulating inflammatory pathways and decreasing pathogen response gene expression
Published in Scientific reports (07-08-2023)“…Airborne particulate matter produced by industrial sources and automobiles has been linked to increased susceptibility to infectious diseases and it is known…”
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The Pathway to Cancer Cachexia: MicroRNA-Regulated Networks in Muscle Wasting Based on Integrative Meta-Analysis
Published in International journal of molecular sciences (22-04-2019)“…Cancer cachexia is a multifactorial syndrome that leads to significant weight loss. Cachexia affects 50%-80% of cancer patients, depending on the tumor type,…”
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The Impact of miR-155-5p on Myotube Differentiation: Elucidating Molecular Targets in Skeletal Muscle Disorders
Published in International journal of molecular sciences (01-02-2024)“…MicroRNAs are small regulatory molecules that control gene expression. An emerging property of muscle miRNAs is the cooperative regulation of transcriptional…”
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RNA-seq analysis reveals modulation of inflammatory pathways by an enriched-triterpene natural extract in mouse and human macrophage cell lines
Published in Heliyon (30-01-2024)“…Chronic inflammation is crucial in developing insulin resistance and type 2 diabetes. Previous studies have shown that a leaf extract of Eucalyptus…”
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MicroRNA-mRNA Co-sequencing Identifies Transcriptional and Post-transcriptional Regulatory Networks Underlying Muscle Wasting in Cancer Cachexia
Published in Frontiers in genetics (29-05-2020)“…Cancer cachexia is a metabolic syndrome with alterations in gene regulatory networks that consequently lead to skeletal muscle wasting. Integrating…”
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Sensibilidad al benzonidazol de cepas de Trypanosoma cruzi sugiere la circulación de cepas naturalmente resistentes en Colombia
Published in Biomédica (01-06-2012)“…Introducción. La enfermedad de Chagas, causada por Trypanosoma cruzi, es uno de los problemas más graves de salud pública en el continente americano. El…”
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Differential microRNA Expression in Fast- and Slow-Twitch Skeletal Muscle of Piaractus mesopotamicus during Growth
Published in PloS one (03-11-2015)“…Pacu (Piaractus mesopotamicus) is a Brazilian fish with a high economic value in pisciculture due to its rusticity and fast growth. Postnatal growth of…”
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Tumor Transcriptome Reveals High Expression of IL-8 in Non-Small Cell Lung Cancer Patients with Low Pectoralis Muscle Area and Reduced Survival
Published in Cancers (26-08-2019)“…Cachexia is a syndrome characterized by an ongoing loss of skeletal muscle mass associated with poor patient prognosis in non-small cell lung cancer (NSCLC)…”
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PUF3 RNA binding protein of Trypanosoma cruzi regulates mitochondrial morphology and function
Published in Heliyon (30-06-2024)“…The RNA-binding PUF proteins are post-transcriptional regulators found throughout the eukaryotic domain. In Trypanosoma cruzi, ten Puf genes termed Puf1 to…”
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Multi-omics characterization of the microbial populations and chemical space composition of a water kefir fermentation
Published in Frontiers in molecular biosciences (02-10-2023)“…In recent years, the popularity of fermented foods has strongly increased based on their proven health benefits and the adoption of new trends among consumers…”
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Osteoglycin inhibition by microRNA miR-155 impairs myogenesis
Published in PloS one (21-11-2017)“…Skeletal myogenesis is a regulated process in which mononucleated cells, the myoblasts, undergo proliferation and differentiation. Upon differentiation, the…”
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The Transcriptomic Landscape of Age-Induced Changes in Human Visceral Fat and the Predicted Omentum-Liver Connectome in Males
Published in Biomedicines (14-05-2023)“…Aging causes alterations in body composition. Specifically, visceral fat mass increases with age and is associated with age-related diseases. The pathogenic…”
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Transcriptome analysis in osmo-primed tomato seeds with enhanced longevity by heat shock treatment
Published in AoB plants (01-10-2020)“…Abstract Seed priming is widely used in commercial seeds and its main function is to accelerate and synchronize seed germination. Undesirably, primed seeds…”
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Trypanosoma cruzi strains resistant to benznidazole occurring in Colombia
Published in Biomédica (01-06-2012)“…Introduction. Chagas disease caused by Trypanosoma cruzi is one of the most serious public health problems in the Americas. Benznidazole is one of two drugs…”
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Transcriptional and post-transcriptional mechanisms that regulate the genetic program in Zika virus-infected macrophages
Published in The international journal of biochemistry & cell biology (01-12-2022)“…Besides our understanding of the effects of ZIKA virus (ZIKV) infection on neural progenitors’ cells the pathogenesis of this RNA virus also involves…”
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Sensibilidad al benzonidazol de cepas de Trypanosoma cruzi sugiere la circulación de cepas naturalmente resistentes en Colombia
Published in Biomédica (30-06-2012)Get full text
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