Search Results - "Fernàndez–del Castillo, Carlos"

Solid pseudopapillary tumors of the pancreas: Specific pathological features predict the likelihood of postoperative recurrence by Marchegiani, Giovanni, Andrianello, Stefano, Massignani, Marta, Malleo, Giuseppe, Maggino, Laura, Paiella, Salvatore, Ferrone, Cristina R., Luchini, Claudio, Scarpa, Aldo, Capelli, Paola, Mino-Kenudson, Mari, Lillemoe, Keith D., Bassi, Claudio, Castillo, Carlos Fernàndez-del, Salvia, Roberto

“…Background Since their introduction in the WHO classification, the incidence of solid pseudopapillary tumors (SPTs) of the pancreas has progressively…”
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Superior Prognostic Importance of Perineural Invasion vs. Lymph Node Involvement After Curative Resection of Duodenal Adenocarcinoma by Cecchini, Stefano, Correa-Gallego, Camilo, Desphande, Vikram, Ligorio, Matteo, Dursun, Abdulmetin, Wargo, Jennifer, Fernàndez-del Castillo, Carlos, Warshaw, Andrew Louis, Ferrone, Cristina Rosa

“…Background Unlike other gastrointestinal tumors, lymph node involvement has not consistently been a negative prognostic factor for survival in patients with…”
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Does Size Matter in Pancreatic Cancer?: Reappraisal of Tumour Dimension as a Predictor of Outcome Beyond the TNM by Marchegiani, Giovanni, Andrianello, Stefano, Malleo, Giuseppe, De Gregorio, Lucia, Scarpa, Aldo, Mino-Kenudson, Mari, Maggino, Laura, Ferrone, Cristina R, Lillemoe, Keith D, Bassi, Claudio, Castillo, Carlos Fernàndez-del, Salvia, Roberto

“…OBJECTIVE:To explore the role of pancreatic ductal adenocarcinoma (PDAC) size on surgical and survival outcomes. BACKGROUND:Tumor size is a prognostic factor…”
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Number of Examined Lymph Nodes and Nodal Status Assessment in Distal Pancreatectomy for Body/Tail Ductal Adenocarcinoma by Malleo, Giuseppe, Maggino, Laura, Ferrone, Cristina R, Marchegiani, Giovanni, Mino-Kenudson, Mari, Capelli, Paola, Rusev, Borislav, Lillemoe, Keith D, Bassi, Claudio, Fernàndez-del Castillo, Carlos, Salvia, Roberto

“…OBJECTIVE:First, to assess the impact of the number of examined lymph nodes (ELNs) on staging and survival after distal pancreatectomy (DP) for pancreatic…”
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Reappraising the Concept of Conditional Survival After Pancreatectomy for Ductal Adenocarcinoma: A Bi-institutional Analysis by Malleo, Giuseppe, Maggino, Laura, Ferrone, Cristina R., Marchegiani, Giovanni, Warshaw, Andrew L., Lillemoe, Keith D., Bassi, Claudio, Castillo, Carlos Fernàndez-del, Salvia, Roberto

“…OBJECTIVE:To reappraise the concept of conditional survival (CS) following pancreatectomy for pancreatic ductal adenocarcinoma (PDAC), accounting for the…”
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Reassessment of the Optimal Number of Examined Lymph Nodes in Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma by Malleo, Giuseppe, Maggino, Laura, Qadan, Motaz, Marchegiani, Giovanni, Ferrone, Cristina R., Paiella, Salvatore, Luchini, Claudio, Mino-Kenudson, Mari, Capelli, Paola, Scarpa, Aldo, Lillemoe, Keith D., Bassi, Claudio, Castillo, Carlos Fernàndez-del, Salvia, Roberto

“…OBJECTIVE:To reappraise the optimal number of examined lymph nodes (ELN) in pancreatoduodenectomy (PD) for pancreatic ductal adenocarcinoma (PDAC). SUMMARY…”
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Radiological and surgical implications of neoadjuvant treatment with FOLFIRINOX for locally advanced and borderline resectable pancreatic cancer by Ferrone, Cristina R, Marchegiani, Giovanni, Hong, Theodore S, Ryan, David P, Deshpande, Vikram, McDonnell, Erin I, Sabbatino, Francesco, Santos, Daniela Dias, Allen, Jill N, Blaszkowsky, Lawrence S, Clark, Jeffrey W, Faris, Jason E, Goyal, Lipika, Kwak, Eunice L, Murphy, Janet E, Ting, David T, Wo, Jennifer Y, Zhu, Andrew X, Warshaw, Andrew L, Lillemoe, Keith D, Fernández-del Castillo, Carlos

“…On the basis of the ACCORD trial, FOLFIRINOX is effective in metastatic pancreatic adenocarcinoma (PDAC), making it a rational choice for locally advanced PDAC…”
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International consensus on definition and criteria of borderline resectable pancreatic ductal adenocarcinoma 2017 by Isaji, Shuji, Mizuno, Shugo, Windsor, John A., Bassi, Claudio, Fernández-del Castillo, Carlos, Hackert, Thilo, Hayasaki, Aoi, Katz, Matthew H.G., Kim, Sun-Whe, Kishiwada, Masashi, Kitagawa, Hirohisa, Michalski, Christoph W., Wolfgang, Christopher L.

“…This statement was developed to promote international consensus on the definition of borderline resectable pancreatic ductal adenocarcinoma (BR-PDAC) which was…”
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851 resected cystic tumors of the pancreas: A 33-year experience at the Massachusetts General Hospital by Valsangkar, Nakul P., MD, Morales-Oyarvide, Vicente, MD, Thayer, Sarah P., MD, PhD, Ferrone, Cristina R., MD, Wargo, Jennifer A., MD, Warshaw, Andrew L., MD, Fernández-del Castillo, Carlos, MD

“…Background The objective of this study was to identify trends in the diagnosis and treatment of cystic neoplasms of the pancreas using a retrospective review…”
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Association Between Pancreatic Fistula and Long-term Survival in the Era of Neoadjuvant Chemotherapy by Hank, Thomas, Sandini, Marta, Ferrone, Cristina R, Rodrigues, Clifton, Weniger, Maximilian, Qadan, Motaz, Warshaw, Andrew L, Lillemoe, Keith D, Fernández-Del Castillo, Carlos

“…In the past decade, the use of neoadjuvant therapy (NAT) has increased for patients with borderline and locally advanced pancreatic ductal adenocarcinoma…”
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Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors by Cejas, Paloma, Drier, Yotam, Dreijerink, Koen M. A., Brosens, Lodewijk A. A., Deshpande, Vikram, Epstein, Charles B., Conemans, Elfi B., Morsink, Folkert H. M., Graham, Mindy K., Valk, Gerlof D., Vriens, Menno R., Castillo, Carlos Fernandez-del, Ferrone, Cristina R., Adar, Tomer, Bowden, Michaela, Whitton, Holly J., Da Silva, Annacarolina, Font-Tello, Alba, Long, Henry W., Gaskell, Elizabeth, Shoresh, Noam, Heaphy, Christopher M., Sicinska, Ewa, Kulke, Matthew H., Chung, Daniel C., Bernstein, Bradley E., Shivdasani, Ramesh A.

“…Most pancreatic neuroendocrine tumors (PNETs) do not produce excess hormones and are therefore considered ‘non-functional’ 1 – 3 . As clinical behaviors vary…”
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Epigenetic regulation of pancreatic adenocarcinoma in the era of cancer immunotherapy by Kawakubo, Kazumichi, Castillo, Carlos Fernandez-del, Liss, Andrew Scott

“…Pancreatic adenocarcinoma is a lethal cancer with poor response to chemotherapy and immune checkpoint inhibitors. Recent studies suggest that epigenetic…”
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Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism by Patra, Krushna C., Kato, Yasutaka, Mizukami, Yusuke, Widholz, Sebastian, Boukhali, Myriam, Revenco, Iulia, Grossman, Elizabeth A., Ji, Fei, Sadreyev, Ruslan I., Liss, Andrew S., Screaton, Robert A., Sakamoto, Kei, Ryan, David P., Mino-Kenudson, Mari, Castillo, Carlos Fernandez-del, Nomura, Daniel K., Haas, Wilhelm, Bardeesy, Nabeel

“…G protein α s (GNAS) mediates receptor-stimulated cAMP signalling, which integrates diverse environmental cues with intracellular responses. GNAS is…”
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Intraductal Papillary Mucinous Neoplasms of the Pancreas by Castillo, Carlos Fernández–del, Adsay, N. Volkan

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PD-L1 and HLA Class I Antigen Expression and Clinical Course of the Disease in Intrahepatic Cholangiocarcinoma by Sabbatino, Francesco, Villani, Vincenzo, Yearley, Jennifer H, Deshpande, Vikram, Cai, Lei, Konstantinidis, Ioannis T, Moon, Christina, Nota, Sjoerd, Wang, Yangyang, Al-Sukaini, Ahmad, Zhu, Andrew X, Goyal, Lipika, Ting, David T, Bardeesy, Nabeel, Hong, Theodore S, Fernandez-del Castillo, Carlos, Tanabe, Kenneth K, Lillemoe, Keith D, Ferrone, Soldano, Ferrone, Cristina R

“…More effective therapy is needed for intrahepatic cholangiocarcinoma (ICC). The encouraging clinical results obtained with checkpoint molecule-specific…”
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IPMN Involving the Main Pancreatic Duct: Biology, Epidemiology, and Long-term Outcomes Following Resection by Marchegiani, Giovanni, Mino-Kenudson, Mari, Sahora, Klaus, Morales-Oyarvide, Vicente, Thayer, Sarah, Ferrone, Cristina, Warshaw, Andrew L, Lillemoe, Keith D, Fernández-del Castillo, Carlos

“…OBJECTIVES:To describe the characteristics of intraductal papillary mucinous neoplasms (IPMNs) with predominant involvement of the main pancreatic duct (MPD),…”
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Caregiver‐reported quality of communication in pancreatic and periampullary cancer by Fong, Zhi Ven, Teinor, Jonathan, Engineer, Lilly, Yeo, Theresa P., Rinaldi, Dee, Greer, Jonathan B., Lavu, Harish, Qadan, Motaz, Johnston, Fabian M., Ferrone, Cristina R., Chang, David C., Yeo, Charles J., Wolfgang, Christopher L., Warshaw, Andrew L., Lillemoe, Keith D., Castillo, Carlos Fernandez‐del, Weiss, Matthew J., Wu, Albert W., Wolff, Jennifer L.

“…Background Communication between caregivers and clinical team members is critical for transitional care, but its quality and potential impact on outcomes are…”
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Impact of next-generation sequencing on the clinical diagnosis of pancreatic cysts by Jones, Martin, MBBS, Zheng, Zongli, MD, PhD, Wang, Jessica, MD, Dudley, Jonathan, MD, PhD, Albanese, Emily, Kadayifci, Abdurrahman, MD, Dias-Santagata, Dora, PhD, Le, Long, MD, Brugge, William R., MD, Castillo, Carlos Fernandez-del, MD, Mino-Kenudson, Mari, MD, Iafrate, A. John, MD, PhD, Pitman, Martha B., MD

“…Background and Aims The value of next-generation sequencing (NGS) of pancreatic cyst fluid relative to the clinical and imaging impression has not been…”
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Role of Tumor-Associated Macrophages in the Clinical Course of Pancreatic Neuroendocrine Tumors (PanNETs) by Cai, Lei, Michelakos, Theodoros, Deshpande, Vikram, Arora, Kshitij S, Yamada, Teppei, Ting, David T, Taylor, Marty S, Castillo, Carlos Fernandez-Del, Warshaw, Andrew L, Lillemoe, Keith D, Ferrone, Soldano, Ferrone, Cristina R

“…This study evaluated the potential role of immune cells and molecules in the pathogenesis and clinical course of pancreatic neuroendocrine tumors (PanNET)…”
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Major Complications Independently Increase Long-Term Mortality After Pancreatoduodenectomy for Cancer by Sandini, M., Ruscic, K. J., Ferrone, C. R., Qadan, M., Eikermann, M., Warshaw, A. L., Lillemoe, K. D., Castillo, Carlos Fernández-del

“…Background Postoperative major morbidity has been associated with worse survival gastrointestinal tumors. This association remains controversial in pancreatic…”
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