Radiotherapy setup displacements in breast cancer patients: 3D surface imaging experience

In this study, we intend to compare two different setup procedures for female breast cancer patients. Imaging in radiotherapy provides a precise localization of the tumour, increasing the accuracy of the treatment delivery in breast cancer. Twenty breast cancer patients who underwent whole breast ra...

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Bibliographic Details
Published in:	Reports of practical oncology and radiotherapy Vol. 23; no. 1; pp. 61 - 67
Main Authors:	Cravo Sá, Ana, Fermento, Ana, Neves, Dalila, Ferreira, Sara, Silva, Teresa, Marques Coelho, Carina, Vaandering, Aude, Roma, Ana, Quaresma, Sérgio, Bonnarens, Emmanuel
Format:	Journal Article
Language:	English
Published:	Poland Elsevier Urban & Partner Sp. z o.o 01-01-2018 Elsevier
Subjects:	3D surface imaging AlignRT Breast cancer Cone beam computed tomography Original research article Whole breast radiotherapy Breast cancer Cone beam computed tomography Whole breast radiotherapy 3D surface imaging AlignRT
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Summary:	In this study, we intend to compare two different setup procedures for female breast cancer patients. Imaging in radiotherapy provides a precise localization of the tumour, increasing the accuracy of the treatment delivery in breast cancer. Twenty breast cancer patients who underwent whole breast radiotherapy (WBRT) were selected for this study. Patients were divided into two groups of ten. Group one (G1) was positioned by tattoos and then the patient positioning was adjusted with the aid of AlignRT (Vision RT, London, UK). In group two (G2), patients were positioned only by tattoos. For both groups, the first 15 fractions were analyzed, a daily kilovoltage (kV) cone beam computed tomography (CBCT) image was made and then the rotational and translational displacements and, posteriorly, the systematic (Σ) and random (σ) errors were analyzed. The comparison of CBCT displacements for the two groups showed a statistically significant difference in the translational left–right (LR) direction (ρ=0.03), considering that the procedure with AlignRT system has smaller lateral displacements. The results of systematic (Σ) and random (σ) errors showed that for translational displacements the group positioned only by tattoos (G2) demonstrated higher values of errors when compared with the group positioned with the aid of AlignRT (G1). AlignRT could help the positioning of breast cancer patients; however, it should be used with another imaging method.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1507-1367 2083-4640
DOI:	10.1016/j.rpor.2017.12.007