Search Results - "Ferman, Tanis J."
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Predicting future rates of tau accumulation on PET
Published in Brain (London, England : 1878) (01-10-2020)“…Clinical trials with anti-tau drugs will need to target individuals at risk of accumulating tau. Our objective was to identify variables available in a…”
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APOE3 -Jacksonville (V236E) variant reduces self-aggregation and risk of dementia
Published in Science translational medicine (29-09-2021)“…Apolipoprotein E ( ) genetic variants have been shown to modify Alzheimer’s disease (AD) risk. We previously identified an variant ( 3-V236E), named…”
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Probable rapid eye movement sleep behavior disorder increases risk for mild cognitive impairment and Parkinson disease: A population-based study
Published in Annals of neurology (01-01-2012)“…Objective: Rapid eye movement sleep behavior disorder (RBD) is associated with neurodegenerative disease and particularly with the synucleinopathies…”
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Validation of the Mayo Sleep Questionnaire to screen for REM sleep behavior disorder in an aging and dementia cohort
Published in Sleep medicine (01-05-2011)“…Abstract Objective To validate a questionnaire focused on rapid eye movement sleep (REM) sleep behavior disorder (RBD) among participants in an aging and…”
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Duration and Pathologic Correlates of Lewy Body Disease
Published in JAMA neurology (01-03-2017)“…Although patients with dementia with Lewy bodies (DLB) have shorter disease duration than patients with Alzheimer disease dementia, little is known about which…”
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Validation of the Mayo Sleep Questionnaire to screen for REM sleep behavior disorder in a community-based sample
Published in Journal of clinical sleep medicine (15-05-2013)“…To validate a questionnaire focused on REM sleep behavior disorder (RBD) in a community-based sample. RBD is a parasomnia manifested by recurrent dream…”
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ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans
Published in Molecular neurodegeneration (11-10-2018)“…Rare coding variants ABI3_rs616338-T and PLCG2_rs72824905-G were identified as risk or protective factors, respectively, for Alzheimer's disease (AD). We…”
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FDG PET metabolic signatures distinguishing prodromal DLB and prodromal AD
Published in NeuroImage clinical (01-01-2021)“…•FDG PET distinguish prodromal DLB from prodromal Alzheimer’s disease.•The topography of hypometabolism in prodromal DLB is consistent with DLB pattern.•Medial…”
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Challenges and opportunities for improving the landscape for Lewy body dementia clinical trials
Published in Alzheimer's research & therapy (29-10-2020)“…Lewy body dementia (LBD), including dementia with Lewy bodies and Parkinson's disease dementia, affects over a million people in the USA and has a substantial…”
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MRI quantitative susceptibility mapping of the substantia nigra as an early biomarker for Lewy body disease
Published in Journal of neuroimaging (01-09-2021)“…ABSTRACT Background and Purpose Neurodegeneration of the substantia nigra in Lewy body disease is associated with iron deposition, which increases the magnetic…”
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Association of REM sleep behavior disorder and neurodegenerative disease may reflect an underlying synucleinopathy
Published in Movement disorders (01-07-2001)“…Our objective was to examine whether rapid eye movement (REM) sleep behavior disorder occurs in disproportionally greater frequency in multiple system atrophy…”
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Regional cortical perfusion on arterial spin labeling MRI in dementia with Lewy bodies: Associations with clinical severity, glucose metabolism and tau PET
Published in NeuroImage clinical (01-01-2018)“…Visually preserved metabolism in posterior cingulate cortex relative to hypometabolism in precuneus and cuneus, the cingulate island sign, is a feature of…”
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A proteomic signature for dementia with Lewy bodies
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (01-12-2019)“…We sought to determine if a proteomic profile approach developed to detect Alzheimer's disease would distinguish patients with Lewy body disease from normal…”
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Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies
Published in Acta neuropathologica communications (29-01-2020)“…Dementia with Lewy bodies (DLB) is a clinically heterogeneous disorder with a substantial burden on healthcare. Despite this, the genetic basis of the disorder…”
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Influences of amyloid-β and tau on white matter neurite alterations in dementia with Lewy bodies
Published in NPJ Parkinson's Disease (03-04-2024)“…Dementia with Lewy bodies (DLB) is a neurodegenerative condition often co-occurring with Alzheimer’s disease (AD) pathology. Characterizing white matter tissue…”
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Mitochondrial genomic variation in dementia with Lewy bodies: association with disease risk and neuropathological measures
Published in Acta neuropathologica communications (14-07-2022)“…Dementia with Lewy bodies (DLB) is clinically diagnosed when patients develop dementia less than a year after parkinsonism onset. Age is the primary risk…”
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Plasma sphingolipid changes with autopsy-confirmed Lewy body or Alzheimer's pathology
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2016)“…Abstract Introduction The clinical and pathological phenotypes of Dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) often overlap. We examined…”
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Association of ABI3 and PLCG2 missense variants with disease risk and neuropathology in Lewy body disease and progressive supranuclear palsy
Published in Acta neuropathologica communications (22-10-2020)“…Missense variants ABI3_rs616338-T and PLCG2_rs72824905-G were previously associated with elevated or reduced risk of Alzheimer's disease (AD), respectively…”
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Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium
Published in Neurology (04-07-2017)“…The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about the clinical and pathologic diagnosis of DLB, updating the previous…”
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Research criteria for the diagnosis of prodromal dementia with Lewy bodies
Published in Neurology (28-04-2020)“…The prodromal phase of dementia with Lewy bodies (DLB) includes (1) mild cognitive impairment (MCI), (2) delirium-onset, and (3) psychiatric-onset…”
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