Search Results - "Ferletta, Maria"

Forced expression of Sox21 inhibits Sox2 and induces apoptosis in human glioma cells by Ferletta, Maria, Caglayan, Demet, Mokvist, Liza, Jiang, Yiwen, Kastemar, Marianne, Uhrbom, Lene, Westermark, Bengt

“…Numerous studies support a role for Sox2 to keep stem cells and progenitor cells in an immature and proliferative state. Coexpression of Sox2 and GFAP has been…”
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Sox10 Has a Broad Expression Pattern in Gliomas and Enhances Platelet-Derived Growth Factor-B–Induced Gliomagenesis by Ferletta, Maria, Uhrbom, Lene, Olofsson, Tommie, Pontén, Fredrik, Westermark, Bengt

“…In a previously published insertional mutagenesis screen for candidate brain tumor genes in the mouse using a Moloney mouse leukemia virus encoding…”
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Identification of Candidate Cancer-Causing Genes in Mouse Brain Tumors by Retroviral Tagging by Johansson, Fredrik K., Brodd, Josefin, Eklöf, Charlotta, Ferletta, Maria, Hesselager, Göran, Tiger, Carl-Fredrik, Uhrbom, Lene, Westermark, Bengt, Croce, Carlo M.

“…Murine retroviruses may cause malignant tumors in mice by insertional mutagenesis of host genes. The use of retroviral tagging as a means of identifying…”
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Laminin α1 Globular Domains 4-5 Induce Fetal Development but Are Not Vital for Embryonic Basement Membrane Assembly by Schéele, Susanne, Falk, Mats, Franzén, Ahnders, Ellin, Fredrik, Ferletta, Maria, Lonai, Peter, Andersson, Björn, Timpl, Rupert, Forsberg, Erik, Ekblom, Peter, Anderson, Kathryn V.

“…During early mouse embryogenesis, each laminin (Lm) chain of the first described Lm, a heterotrimer of α1, β1, and γ1 chains (Lm-1), is essential for basement…”
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Opposing Roles of Integrin α6Aβ1 and Dystroglycan in Laminin-mediated Extracellular Signal-regulated Kinase Activation by Ferletta, Maria, Kikkawa, Yamato, Yu, Hao, Talts, Jan F., Durbeej, Madeleine, Sonnenberg, Arnoud, Timpl, Rupert, Campbell, Kevin P., Ekblom, Peter, Genersch, Elke

“…Laminin–integrin interactions can in some settings activate the extracellular signal-regulated kinases (ERKs) but the control mechanisms are poorly understood…”
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Distribution of Dystroglycan in Normal Adult Mouse Tissues by Durbeej, Madeleine, Henry, Michael D, Ferletta, Maria, Campbell, Kevin P, Ekblom, Peter

“…Dystroglycan is a cell surface protein which, in muscle, links the extracellular matrix protein laminin-2 to the intracellular cytoskeleton. Dystroglycan also…”
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Sox21 inhibits glioma progression in vivo by forming complexes with Sox2 and stimulating aberrant differentiation by Caglayan, Demet, Lundin, Erika, Kastemar, Marianne, Westermark, Bengt, Ferletta, Maria

“…Sox2 is a transcription factor in neural stem cells and keeps the cells immature and proliferative. Sox2 is expressed in primary human glioma such as…”
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Sox21 inhibits glioma progression in vivo by forming complexes with Sox2 and stimulating aberrant differentiation: Sox21 inhibits glioma progression by Caglayan, Demet, Lundin, Erika, Kastemar, Marianne, Westermark, Bengt, Ferletta, Maria

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Sox21 inhibits glioma progression in vivo by reducing Sox2 and stimulating aberrant differentiation by Caglayan, Demet, Lundin, Erika, Kastemar, Marianne, Westermark, Bengt, Ferletta, Maria

“…Sox2 is a transcription factor in neural stem cells and keeps the cells immature and proliferative. Sox2 is expressed in primary human glioma such as…”
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Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines by Swartling, F J, Ferletta, M, Kastemar, M, Weiss, W A, Westermark, B

“…Earlier we used a glioma model to identify loci in the mouse genome, which were repeatedly targeted by platelet-derived growth factor (PDGF)-containing Moloney…”
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Abstract 66: Inhibition of glioma cell proliferation and tumor development by Sox21 by Caglayan, Demet, Kastemar, Marianne, Westermark, Bengt, Ferletta, Maria

“…Abstract Sox2 and Sox21 are two transcription factors important for the developing, as well as the adult, CNS, and they are often co-expressed. Sox2 is an…”
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Canine mammary tumors contain cancer stem-like cells and form spheroids with an embryonic stem cell signature by Ferletta, Maria, Grawé, Jan, Hellmén, Eva

“…We have investigated the presence of tentative stem-like cells in the canine mammary tumor cell line CMT-U229. This cell line is established from an atypical…”
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Induced Expression of Sox21 Inhibits Glioma Progression in Vivo by Stimulating Aberrant Differentiation by Ferletta, Maria, Caglayan, Demet, Lundin, Erika, Kastemar, Marianne, Westermark, Bengt

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Identification of laminin-10/11 as a strong cell adhesive complex for a normal and a malignant human epithelial cell line by Ferletta, M, Ekblom, P

“…Laminins are heterotrimeric proteins of basement membranes. More than 50 different trimers may exist. Laminin-10 (alpha5beta1gamma1 rather than laminin-1…”
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Restricted distribution of laminin α1 chain in normal adult mouse tissues by Falk, Mats, Ferletta, Maria, Forsberg, Erik, Ekblom, Peter

“…The distribution of laminin α1 chain in adult mouse tissue was determined by immunofluorescence using monoclonal antibody 200, reacting with the globular…”
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Integrin αvβ3 binding to human α5-laminins facilitates FGF-2- and VEGF-induced proliferation of human ECV304 carcinoma cells by Genersch, Elke, Ferletta, Maria, Virtanen, Ismo, Haller, Hermann, Ekblom, Peter

“…Human ECV304 cells respond reproducibly by tube formation to complex basement membrane matrices. Laminins are major glycoproteins of basement membranes. We…”
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Laminin {alpha}1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly by Schéele, Susanne, Falk, Mats, Franzén, Ahnders, Ellin, Fredrik, Ferletta, Maria, Lonai, Peter, Andersson, Björn, Timpl, Rupert, Forsberg, Erik, Ekblom, Peter

“…basement membrane (BM) assembly, which is required for pregastrulation development. Individual domains may have other functions, not necessarily structural…”
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Integrin (alpha)v(beta)3 binding to human (alpha)5-laminins facilitates FGF-2- and VEGF-induced proliferation of human ECV304 carcinoma cells by Genersch, Elke, Ferletta, Maria, Virtanen, Ismo, Haller, Hermann, Ekblom, Peter

“…Human ECV304 cells respond reproducibly by tube formation to complex basement membrane matrices. Laminins are major glycoproteins of basement membranes. We…”
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Integrin alphavbeta3 binding to human alpha5-laminins facilitates FGF-2- and VEGF-induced proliferation of human ECV304 carcinoma cells by Genersch, Elke, Ferletta, Maria, Virtanen, Ismo, Haller, Hermann, Ekblom, Peter

“…Human ECV304 cells respond reproducibly by tube formation to complex basement membrane matrices. Laminins are major glycoproteins of basement membranes. We…”
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Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly by Schéele, Susanne, Falk, Mats, Franzén, Ahnders, Ellin, Fredrik, Ferletta, Maria, Lonai, Peter, Andersson, Björn, Timpl, Rupert, Forsberg, Erik, Ekblom, Peter

“…During early mouse embryogenesis, each laminin (Lm) chain of the first described Lm, a heterotrimer of alpha1, beta1, and gamma1 chains (Lm-1), is essential…”
Get full text