Search Results - "Ferioli, Cristian"
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Pharmacological characterisation of CR6086, a potent prostaglandin E2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug
Published in Arthritis research & therapy (01-03-2018)“…BACKGROUNDProstaglandin E2 (PGE2) acts via its EP4 receptor as a cytokine amplifier (e.g., interleukin [IL]-6) and induces the differentiation and expansion of…”
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Biochemical and Crystallographic Characterization of Ferredoxin−NADP+ Reductase from Nonphotosynthetic Tissues
Published in Biochemistry (Easton) (04-12-2001)“…Distinct forms of ferredoxin−NADP+ reductase are expressed in photosynthetic and nonphotosynthetic plant tissues. Both enzymes catalyze electron transfer…”
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Pharmacological characterisation of CR6086, a potent prostaglandin E 2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug
Published in Arthritis research & therapy (01-03-2018)“…Prostaglandin E (PGE ) acts via its EP4 receptor as a cytokine amplifier (e.g., interleukin [IL]-6) and induces the differentiation and expansion of…”
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4
Synthesis, pharmacophore modeling and in vitro activity of 10,11-dihydrodibenzo[b,f]oxepine-4-carboxamide derivatives as novel and potent antagonists of the prostaglandin EP₄ receptor
Published in Bioorganic & medicinal chemistry letters (01-11-2011)“…The construction of a EP₄ antagonists pharmacophore model and the discovery of a highly potent oxepinic series of EP₄ antagonists is discussed. Compound 1a…”
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Synthesis, pharmacophore modeling and in vitro activity of 10,11-dihydrodibenzo[b,f]oxepine-4-carboxamide derivatives as novel and potent antagonists of the prostaglandin EP sub(4 receptor)
Published in Bioorganic & medicinal chemistry letters (01-11-2011)“…The construction of a EP sub(4 antagonists pharmacophore model and the discovery of a highly potent oxepinic series of EP) sub(4) antagonists is discussed…”
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Synthesis, pharmacophore modeling and in vitro activity of 10,11-dihydrodibenzo[ b, f]oxepine-4-carboxamide derivatives as novel and potent antagonists of the prostaglandin EP 4 receptor
Published in Bioorganic & medicinal chemistry letters (2011)“…The construction of a EP 4 antagonists pharmacophore model and the discovery of a highly potent oxepinic series of EP 4 antagonists is discussed. Compound 1a…”
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Journal Article