Search Results - "Ferguson, M W J"

Transforming growth factor-beta 1, 2, 3 and receptor type I and II in diabetic foot ulcers by Jude, E. B., Blakytny, R., Bulmer, J., Boulton, A. J. M., Ferguson, M. W. J.

“…Aims To study the distribution of transforming growth factor‐beta (TGF‐β) 1, 2 and 3, and TGF‐β receptor types I and II in diabetic foot ulcers, diabetic skin…”
Get full text

A New Quantitative Scale for Clinical Scar Assessment by Beausang, E, Floyd, H, Dunn, K W, Orton, C I, Ferguson, M W. J

“…Wound healing in adult human skin results in varying degrees of scar formation, ranging clinically from fine asymptomatic scars to problematic hypertrophic and…”
Get full text

Skin scarring by Bayat, A, McGrouther, D A, Ferguson, M W J

“…Deciding whether to treat a scar or leave it alone depends on accurate diagnosis of scar type and scar site, symptoms, severity, and stigma…”
Get full text

Current scales for assessing human scarring: A review by Durani, Piyush, McGrouther, D.A, Ferguson, M.W.J

“…Summary Patients can have wide-ranging problems related to scars, in terms of cosmesis, function, symptoms, psychological problems and overall quality of life…”
Get full text

Randomized phase II clinical trial of avotermin versus placebo for scar improvement by McCollum, P. T., Bush, J. A., James, G., Mason, T., O'Kane, S., McCollum, C., Krievins, D., Shiralkar, S., Ferguson, M. W. J.

“…Background: Scarring is a major problem following skin injury. In early clinical trials, transforming growth factor β3 (avotermin) improved scar appearance…”
Get full text

The reinnervation pattern of wounds and scars may explain their sensory symptoms by Henderson, J., Terenghi, G., McGrouther, D.A., Ferguson, M.W.J.

“…Anaesthesia, pruritis and pain are common in cutaneous scars. The reinnervation pattern of healing wounds and scars might help to explain these symptoms, as…”
Get full text

The role of nitric oxide synthase isoforms and arginase in the pathogenesis of diabetic foot ulcers : possible modulatory effects by transforming growth factor beta 1 by JUDE, E. B, BOULTON, A. J. M, FERGUSON, M. W. J, APPLETON, I

“…L-arginine, an amino acid involved in wound healing, is metabolised by one of two pathways; nitric oxide synthase and arginase. If metabolised by nitric oxide…”
Get full text

Genetic susceptibility to keloid disease: Transforming growth factor β receptor gene polymorphisms are not associated with keloid disease by Bayat, Ardeshir, Bock, O., Mrowietz, U., Ollier, W. E. R., Ferguson, M. W. J.

“…:  Keloid disease (KD) is an abnormal form of scarring with a familial predisposition. Genetic studies have yet to identify the genes involved in KD…”
Get full text

Perivascular cells in a skin graft are rapidly repopulated by host cells by O'Ceallaigh, S, Herrick, S.E, Bennett, W.R, Bluff, J.E, Ferguson, M.W.J, McGrouther, D.A

“…Summary Survival of grafted tissues is dependent upon revascularisation. This study investigated revascularisation in a murine skin graft model, using two…”
Get full text

Molecular and Cellular Basis of Regeneration and Tissue Repair: Skin stem and progenitor cells: using regeneration as a tissue-engineering strategy by Metcalfe, A. D., Ferguson, M. W. J.

“… Cell plasticity and mesenchymal-epithelial interactions are regarded as a hallmark of embryonic development and are not believed to occur extensively in the…”
Get full text

Skin stem and progenitor cells: using regeneration as a tissue-engineering strategy by Metcalfe, A D, Ferguson, M W J

“…Cell plasticity and mesenchymal-epithelial interactions are regarded as a hallmark of embryonic development and are not believed to occur extensively in the…”
Get full text

Mannose-6-phosphate facilitates early peripheral nerve regeneration in thy-1-YFP-H mice by Harding, A.J, Christmas, C.R, Ferguson, M.W.J, Loescher, A.R, Robinson, P.P, Boissonade, F.M

“…Highlights • We have visualized and quantified nerve regeneration at an axonal level. • Axons cross the repair site more directly following mannose-6-phosphate…”
Get full text

The cell biology of suturing tendons by Wong, J.K.F., Alyouha, S., Kadler, K.E., Ferguson, M.W.J., McGrouther, D.A.

“…Trauma by suturing tendon form areas devoid of cells termed “acellular zones” in the matrix. This study aimed to characterise the cellular insult of suturing…”
Get full text

Changes in the extracellular matrix of the normal human breast during the menstrual cycle by FERGUSON, J. E, SCHOR, A. M, HOWELL, A, FERGUSON, M. W. J

“…The normal human mammary gland undergoes a well defined sequence of histological changes in both epithelial and stromal compartments during the menstrual…”
Get full text

Keloid disease: clinical relevance of single versus multiple site scars by Bayat, A., Arscott, G., Ollier, W.E.R., Mc Grouther, D.A., Ferguson, M.W.J.

“…Much of our current understanding of keloid disease (KD) is based on anecdote rather than objective observation and statistical analysis. To elucidate further…”
Get full text

Life-Sciences R&D, National Prosperity, and Industrial Competitiveness by Fears, R., Ferguson, M. W. J., Stewart, W., Poste, G.

“…Formal science and technology policies are needed to ensure that society continues to reap the social and economic benefits of research in an era of severe…”
Get full text

Size-dependent pigmentation-pattern formation in embryos of Alligator mississippiensis: time of initiation of pattern generation mechanism by Murray, James Dickson, Deeming, D. C., Ferguson, M. W. J.

“…The pigmentation pattern of Alligator</italic mississippiensis was examined. The number of white stripes on the dorsal side of embryos (stages 21–28) and…”
Get full text

Description of site-specific morphology of keloid phenotypes in an Afrocaribbean population by Bayat, A, Arscott, G, Ollier, W.E.R, Ferguson, M.W.J, Mc Grouther, D.A

“…By examining the keloid scars of 211 Afrocaribbean patients presenting to the Plastic Surgery unit in Kingston, Jamaica, we have described site-specific…”
Get full text

The effect of incubation temperature on yolk lipid parameters during embryonic development of the alligator (Alligator mississippiensis) by Noble, R. C., Deeming, D. C., Ferguson, M. W. J., McCartney, R.

“…The effect of incubation temperature (30 and 33°C) on yolk lipid uptake and changes in the alligator has been studied. Notable changes occurred in the lipid…”
Get full text

Scar–free healing: from embryonic mechanisms to adult therapeutic intervention by Ferguson, Mark W. J., O'Kane, Sharon

“…In man and domestic animals, scarring in the skin after trauma, surgery, burn or sports injury is a major medical problem, often resulting in adverse…”
Get full text