Search Results - "Ferguson, Harriet R."

Fibroblast Growth Factor Receptors (FGFRs) and Noncanonical Partners in Cancer Signaling by Ferguson, Harriet R, Smith, Michael P, Francavilla, Chiara

“…Increasing evidence indicates that success of targeted therapies in the treatment of cancer is context-dependent and is influenced by a complex crosstalk…”
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Spatially resolved phosphoproteomics reveals fibroblast growth factor receptor recycling-driven regulation of autophagy and survival by Watson, Joanne, Ferguson, Harriet R., Brady, Rosie M., Ferguson, Jennifer, Fullwood, Paul, Mo, Hanyi, Bexley, Katherine H., Knight, David, Howell, Gareth, Schwartz, Jean-Marc, Smith, Michael P., Francavilla, Chiara

“…Receptor Tyrosine Kinase (RTK) endocytosis-dependent signalling drives cell proliferation and motility during development and adult homeostasis, but is…”
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Reciprocal priming between receptor tyrosine kinases at recycling endosomes orchestrates cellular signalling outputs by Smith, Michael P, Ferguson, Harriet R, Ferguson, Jennifer, Zindy, Egor, Kowalczyk, Katarzyna M, Kedward, Thomas, Bates, Christian, Parsons, Joseph, Watson, Joanne, Chandler, Sarah, Fullwood, Paul, Warwood, Stacey, Knight, David, Clarke, Robert B, Francavilla, Chiara

“…Integration of signalling downstream of individual receptor tyrosine kinases (RTKs) is crucial to fine‐tune cellular homeostasis during development and in…”
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Differential responses to kinase inhibition in FGFR2-addicted triple negative breast cancer cells: a quantitative phosphoproteomics study by Cunningham, Debbie L., Sarhan, Adil R., Creese, Andrew J., Larkins, Katherine P. B., Zhao, Hongyan, Ferguson, Harriet R., Brookes, Katie, Marusiak, Anna A., Cooper, Helen J., Heath, John K.

“…Fibroblast Growth Factor (FGF) dependent signalling is frequently activated in cancer by a variety of different mechanisms. However, the downstream signal…”
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Phosphoproteomics predict response to midostaurin plus chemotherapy in independent cohorts of FLT3-mutated acute myeloid leukaemia by Borek, Weronika E., Nobre, Luis, Pedicona, S. Federico, Campbell, Amy E., Christopher, Josie A., Nawaz, Nazrath, Perkins, David N., Moreno-Cardoso, Pedro, Kelsall, Janet, Ferguson, Harriet R., Patel, Bela, Gallipoli, Paolo, Arruda, Andrea, Ambinder, Alex J., Thompson, Andrew, Williamson, Andrew, Ghiaur, Gabriel, Minden, Mark D., Gribben, John G., Britton, David J., Cutillas, Pedro R., Dokal, Arran D.

“…Acute myeloid leukaemia (AML) is a bone marrow malignancy with poor prognosis. One of several treatments for AML is midostaurin combined with intensive…”
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S124: PHOSPHOPROTEOMICS ACCURATELY PREDICTS RESPONSES TO MIDOSTAURIN PLUS CHEMOTHERAPY IN TWO INDEPENDENT COHORTS OF FLT3 MUTANT‐POSITIVE ACUTE MYELOID LEUKAEMIA by Dokal, Arran, Borek, Weronika E., Nobre, Luis, Federico Pedicona, Salvatore, Wrench, Bela, Gallipoli, Paolo, Arruda, Andrea, Campbell, Amy E., Nawaz, Nazrath, Ferguson, Harriet R., Perkins, David N., Moreno‐Cardoso, Pedro, Thompson, Andrew, Williamson, Andrew J.K., Minden, Mark D., Gribben, John G., Britton, David J., Cutillas, Pedro R.

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Phosphoproteomics predict response to midostaurin plus chemotherapy in independent cohorts of FLT3-mutated acute myeloid leukaemiaResearch in context by Weronika E. Borek, Luis Nobre, S. Federico Pedicona, Amy E. Campbell, Josie A. Christopher, Nazrath Nawaz, David N. Perkins, Pedro Moreno-Cardoso, Janet Kelsall, Harriet R. Ferguson, Bela Patel, Paolo Gallipoli, Andrea Arruda, Alex J. Ambinder, Andrew Thompson, Andrew Williamson, Gabriel Ghiaur, Mark D. Minden, John G. Gribben, David J. Britton, Pedro R. Cutillas, Arran D. Dokal

“…Background: Acute myeloid leukaemia (AML) is a bone marrow malignancy with poor prognosis. One of several treatments for AML is midostaurin combined with…”
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