Search Results - "Ferguson, Autumn"

Prior viral infection primes cross-reactive CD8+ T cells that respond to mouse heart allografts by Khorki, M Eyad, Shi, Tiffany, Cianciolo, Eileen E, Burg, Ashley R, Chukwuma, P Chukwunalu, Picarsic, Jennifer L, Morrice, Mary K, Woodle, E Steve, Maltzman, Jonathan S, Ferguson, Autumn, Katz, Jonathan D, Baker, Brian M, Hildeman, David A

“…Significant evidence suggests a connection between transplant rejection and the presence of high levels of pre-existing memory T cells. Viral infection can…”
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Optimal Hypoxia Regulates Human iPSC-Derived Liver Bud Differentiation through Intercellular TGFB Signaling by Ayabe, Hiroaki, Anada, Takahisa, Kamoya, Takuo, Sato, Tomoya, Kimura, Masaki, Yoshizawa, Emi, Kikuchi, Shunyuu, Ueno, Yasuharu, Sekine, Keisuke, Camp, J. Gray, Treutlein, Barbara, Ferguson, Autumn, Suzuki, Osamu, Takebe, Takanori, Taniguchi, Hideki

“…Timely controlled oxygen (O2) delivery is crucial for the developing liver. However, the influence of O2 on intercellular communication during hepatogenesis is…”
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High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell–Derived Organoids by Shinozawa, Tadahiro, Kimura, Masaki, Cai, Yuqi, Saiki, Norikazu, Yoneyama, Yosuke, Ouchi, Rie, Koike, Hiroyuki, Maezawa, Mari, Zhang, Ran-Ran, Dunn, Andrew, Ferguson, Autumn, Togo, Shodai, Lewis, Kyle, Thompson, Wendy L., Asai, Akihiro, Takebe, Takanori

“…Preclinical identification of compounds at risk of causing drug induced liver injury (DILI) remains a significant challenge in drug development, highlighting a…”
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Modelling human hepato-biliary-pancreatic organogenesis from the foregut–midgut boundary by Koike, Hiroyuki, Iwasawa, Kentaro, Ouchi, Rie, Maezawa, Mari, Giesbrecht, Kirsten, Saiki, Norikazu, Ferguson, Autumn, Kimura, Masaki, Thompson, Wendy L., Wells, James M., Zorn, Aaron M., Takebe, Takanori

“…Organogenesis is a complex and interconnected process that is orchestrated by multiple boundary tissue interactions 1 – 7 . However, it remains unclear how…”
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Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids by Ouchi, Rie, Togo, Shodai, Kimura, Masaki, Shinozawa, Tadahiro, Koido, Masaru, Koike, Hiroyuki, Thompson, Wendy, Karns, Rebekah A., Mayhew, Christopher N., McGrath, Patrick S., McCauley, Heather A., Zhang, Ran-Ran, Lewis, Kyle, Hakozaki, Shoyo, Ferguson, Autumn, Saiki, Norikazu, Yoneyama, Yosuke, Takeuchi, Ichiro, Mabuchi, Yo, Akazawa, Chihiro, Yoshikawa, Hiroshi Y., Wells, James M., Takebe, Takanori

“…Human organoid systems recapitulate in vivo organ architecture yet fail to capture complex pathologies such as inflammation and fibrosis. Here, using 11…”
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High-Fidelity Drug Induced Liver Injury Screen Using Human PSC-derived Organoids by Shinozawa, Tadahiro, Kimura, Masaki, Cai, Yuqi, Saiki, Norikazu, Yoneyama, Yosuke, Ouchi, Rie, Koike, Hiroyuki, Maezawa, Mari, Zhang, Ran-Ran, Dunn, Andrew, Ferguson, Autumn, Togo, Shodai, Lewis, Kyle, Thompson, Wendy, Asai, Akihiro, Takebe, Takanori

“…Human liver organoid (HLO) based screening system, termed LoT assay, will offer an opportunity to analyze cholestatic pathology specific to developing drugs…”
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Mechanisms of Sertoli cell insulin-like growth factor (IGF)-binding protein-3 regulation by IGF-I and adenosine 3',5'-monophosphate by Smith, E P, Cheung, P T, Ferguson, A, Chernausek, S D

“…FSH, which stimulates cAMP in the Sertoli cell, markedly lowers the concentration of insulin-like growth factor-binding protein-3 (IGFBP-3) in Sertoli…”
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