Search Results - "Ferguson, Andrew R."

Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells by Ferguson, Andrew R., Youd, Michele E., Corley, Ronald B.

“…Secreted IgM and complement are important mediators in the optimal initiation of primary T-dependent humoral immune responses. Secreted IgM serves as a natural…”
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Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results by Palmer, Christine D., Rappaport, Amy R., Davis, Matthew J., Hart, Meghan G., Scallan, Ciaran D., Hong, Sue-Jean, Gitlin, Leonid, Kraemer, Lauren D., Kounlavouth, Sonia, Yang, Aaron, Smith, Lindsey, Schenk, Desiree, Skoberne, Mojca, Taquechel, Kiara, Marrali, Martina, Jaroslavsky, Jason R., Nganje, Charmaine N., Maloney, Elizabeth, Zhou, Rita, Navarro-Gomez, Daniel, Greene, Adrienne C., Grotenbreg, Gijsbert, Greer, Renee, Blair, Wade, Cao, Minh Duc, Chan, Shawn, Bae, Kyounghwa, Spira, Alexander I., Roychowdhury, Sameek, Carbone, David P., Henick, Brian S., Drake, Charles G., Solomon, Benjamin J., Ahn, Daniel H., Mahipal, Amit, Maron, Steve B., Johnson, Benny, Rousseau, Raphael, Yelensky, Roman, Liao, Chih-Yi, Catenacci, Daniel V. T., Allen, Andrew, Ferguson, Andrew R., Jooss, Karin

“…Checkpoint inhibitor (CPI) therapies provide limited benefit to patients with tumors of low immune reactivity. T cell-inducing vaccines hold promise to exert…”
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Synergistic roles of IgM and complement in antigen trapping and follicular localization by Youd, Michele E., Ferguson, Andrew R., Corley, Ronald B.

“…We have investigated the roles of IgM and complement (C) in the enhancement of primary immune responses and the localization of protein antigen (Ag) in the…”
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A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results by Rappaport, Amy R., Kyi, Chrisann, Lane, Monica, Hart, Meghan G., Johnson, Melissa L., Henick, Brian S., Liao, Chih-Yi, Mahipal, Amit, Shergill, Ardaman, Spira, Alexander I., Goldman, Jonathan W., Scallan, Ciaran D., Schenk, Desiree, Palmer, Christine D., Davis, Matthew J., Kounlavouth, Sonia, Kemp, Lindsey, Yang, Aaron, Li, Yaojun John, Likes, Molly, Shen, Annie, Boucher, Gregory R., Egorova, Milana, Veres, Robert L., Espinosa, J. Aaron, Jaroslavsky, Jason R., Kraemer Tardif, Lauren D., Acrebuche, Lindsey, Puccia, Christopher, Sousa, Leiliane, Zhou, Rita, Bae, Kyounghwa, Hecht, J. Randolph, Carbone, David P., Johnson, Benny, Allen, Andrew, Ferguson, Andrew R., Jooss, Karin

“…Therapeutic vaccines that elicit cytotoxic T cell responses targeting tumor-specific neoantigens hold promise for providing long-term clinical benefit to…”
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CD8 T Cells Activated in Distinct Lymphoid Organs Differentially Express Adhesion Proteins and Coexpress Multiple Chemokine Receptors by Ferguson, Andrew R, Engelhard, Victor H

“…Previous work from this laboratory showed that generation of memory CD8 T cells by different immunization routes correlates with control of tumors growing in…”
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Differential Expression of Homing Receptor Ligands on Tumor-Associated Vasculature that Control CD8 Effector T-cell Entry by Woods, Amber N, Wilson, Ashley L, Srivinisan, Nithya, Zeng, Jianhao, Dutta, Arun B, Peske, J David, Tewalt, Eric F, Gregg, Randal K, Ferguson, Andrew R, Engelhard, Victor H

“…Although CD8 T cells are critical for controlling tumors, how they are recruited and home to primary and metastatic lesions is incompletely understood. We…”
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Accumulation of marginal zone B cells and accelerated loss of follicular dendritic cells in NF-κB p50-deficient mice by Ferguson, Andrew R, Corley, Ronald B

“…Abstract Background Marginal zone (MZ) B cells play important roles in the early phases of humoral immune responses. In addition to possessing an inherent…”
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Activated CD8 T Cells Redistribute to Antigen-Free Lymph Nodes and Exhibit Effector and Memory Characteristics by Brinkman, C. Colin, Sheasley-O'Neill, Stacey L, Ferguson, Andrew R, Engelhard, Victor H

“…Exogenous dendritic cells display restricted trafficking when injected in vivo and stimulate CD8 T cell responses that are localized to a small number of…”
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The Assumptions Underlying Eco-Footprinting by Ferguson, Andrew R. B.

“…In essence, the concept of a person's ecological footprint is simple: it is the area of land needed to support permanently a specified lifestyle. But in…”
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Dendritic Cell Immunization Route Determines Integrin Expression and Lymphoid and Nonlymphoid Tissue Distribution of CD8 T Cells by Sheasley-O'Neill, Stacey L, Brinkman, C. Colin, Ferguson, Andrew R, Dispenza, Melanie C, Engelhard, Victor H

“…Exogenous dendritic cells (bone marrow-derived dendritic cell (BMDC)) display restricted trafficking in vivo after injection into mice, but the route(s) by…”
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Strategies and challenges in eliciting immunity to melanoma by Ferguson, Andrew R, Nichols, Lisa A, Zarling, Angela L, Thompson, Elizabeth D, Brinkman, C. Colin, Hargadon, Kristian M, Bullock, Timothy N, Engelhard, Victor H

“…The ability of CD8⁺ T cells to recognize melanoma tumors has led to the development of immunotherapeutic approaches that use the antigens CD8⁺ T cells…”
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Population and the Demise of Cheap Energy by Ferguson, Andrew R. B.

“…Standard of living is determined in part by the availability of ecological resources, and in part by the availability of “cheap energy.” The demise of cheap…”
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Comments on eco-footprinting by Ferguson, Andrew R.B.

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Phase 2/3, randomized, open-label study of an individualized neoantigen vaccine (self-amplifying mRNA and adenoviral vectors) plus immune checkpoint blockade as maintenance for patients with newly diagnosed metastatic colorectal cancer (GRANITE) by Hecht, J. Randolph, Shergill, Ardaman, Goldstein, Mark Gregory, Fang, Bruno, Cho, May Thet, Lenz, Heinz-Josef, Berim, Lyudmyla Derby, Oberstein, Paul Eliezer, Safyan, Rachael A, Sawhney, Vivek, Soares, Heloisa P., Spigel, David R., Spira, Alexander I., Ferguson, Andrew R., Chauder, Brian, Starodub, Alexander

“…TPS3635 Background: Treatment options for most patients with metastatic colorectal cancer (mCRC) are largely limited to cytotoxic chemotherapy, with little…”
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Letters: A Critique of Meyerson's "Population, Development and Global Warming: Averting the Tragedy of the Climate Commons" by Ferguson, Andrew R. B.

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Personalized viral-based prime/boost immunotherapy targeting patient-specific or shared neoantigens: Immunogenicity, safety, and efficacy results from two ongoing phase I studies by Drake, Charles G., Johnson, Melissa Lynne, Spira, Alexander I., Manji, Gulam Abbas, Carbone, David Paul, Henick, Brian S., Ingham, Matthew, Liao, Chih-Yi, Roychowdhury, Sameek, Kyi, Chrisann, Basciano, Paul Andrew, Bournazou, Eirini, Abhyankar, Jesse, Bezawada, Ashish, Kounavouth, Sonia, Schenk, Desiree, Ferguson, Andrew R., Rousseau, Raphael F., Catenacci, Daniel V.T.

“…Abstract only 3137 Background: Neoantigens are key targets of a tumor-specific immune response and CD8 T cells targeting neoantigens drive clinical benefit in…”
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Intractable Limits to a Sustainable Human Population by Ferguson, Andrew RB

“…The pressing need for a much smaller world population arises for two reasons. Humans are emitting about two and a half times as much carbon as the maximum…”
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CD8 T cells activated in distinct lymphoid organs differentially express adhesion proteins and co-express multiple chemokine receptors1 by Ferguson, Andrew R., Engelhard, Victor H.

“…Previous work from this laboratory showed that generation of memory CD8 T cells by different immunization routes correlates with control of tumors growing in…”
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Abstract 2267: HLA-DR-restricted CD4 T cell responses to KRAS G12C in healthy donors linked to bacterial mimotope: lessons for KRAS neoantigen vaccines in cancer patients by Palmer, Christine D., Hart, Meghan G., Kounlavouth, Sonia, Venkatraman, Harshni, Kraemer, Lauren D., Marrali, Martina, Dominguez, Calixto, Chowdhury, Fatema Z., Jaroslavsky, Jason R., Arcebuche, Lindsey, Hernandez, Lorenzo, Adeoye, Bukola, Cuison, Severino, Rappaport, Amy R., Boucher, Greg, Lane, Monica, Rotunno, Melissa, Avocetien, Kenneth, Sousa, Leiliane, Puccia, Chris, Likes, Molly, Vegesna, Rahul, Zhou, Rita, Mantilla, Alexis, Davis, Matthew J., Dhanik, Ankur, Johnson, Melissa, Ferguson, Andrew R., Jooss, Karin

“…Abstract Mutations in the KRAS gene are among the most common driver mutations in cancer. Targeting KRAS G12C mutations has shown some promise in clinical…”
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Activated CD8 T cells redistribute to antigen-free lymph nodes and exhibit effector and memory characteristics1 by Brinkman, C. Colin, Sheasley-O’Neill, Stacey L., Ferguson, Andrew R., Engelhard, Victor H.

“…“This is an author-produced version of a manuscript accepted for publication in The Journal of Immunology (The JI). The American Association of Immunologists,…”
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