Search Results - "Fenwick, Mark A"

Nicotine exposure is associated with targeted impairments in primordial follicle phenotype in cultured neonatal mouse ovaries by Idrees, Sara M., Waite, Sarah L., Granados Aparici, Sofia, Fenwick, Mark A.

“…The ovarian reserve consists of a limited supply of primordial follicles (PFs), each containing an oocyte surrounded by a layer of granulosa cells (GCs). PFs…”
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SMAD3 directly regulates cell cycle genes to maintain arrest in granulosa cells of mouse primordial follicles by Granados-Aparici, Sofia, Hardy, Kate, Franks, Stephen, Sharum, Isam B., Waite, Sarah L., Fenwick, Mark A.

“…Primordial follicles, consisting of granulosa cell (GC)-enveloped oocytes are maintained in a state of developmental arrest until activated to grow. The…”
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Influence of energy balance on the somatotrophic axis and matrix metalloproteinase expression in the endometrium of the postpartum dairy cow by Wathes, D Claire, Cheng, Zhangrui, Fenwick, Mark A, Fitzpatrick, Richard, Patton, Joe

“…Postpartum dairy cows enter a period of negative energy balance (NEB) associated with low circulating IGF1, during which the uterus must undergo extensive…”
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IGF1 induces up-regulation of steroidogenic and apoptotic regulatory genes via activation of phosphatidylinositol-dependent kinase/AKT in bovine granulosa cells by Mani, Arul Murugan, Fenwick, Mark A, Cheng, Zhangrui, Sharma, Mohan K, Singh, Dheer, Wathes, D Claire

“…IGF1, a potent stimulator of cellular proliferation, differentiation and development, regulates granulosa cell steroidogenesis and apoptosis during follicular…”
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Interrelationships between negative energy balance (NEB) and IGF regulation in liver of lactating dairy cows by Fenwick, Mark A., Fitzpatrick, Richard, Kenny, David A., Diskin, Michael G., Patton, Joseph, Murphy, John J., Wathes, D. Claire

“…In dairy cows, negative energy balance (NEB) during the early post-partum period is associated with major alterations in the growth hormone-insulin-like growth…”
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Bmi1 facilitates primitive endoderm formation by stabilizing Gata6 during early mouse development by Lavial, Fabrice, Bessonnard, Sylvain, Ohnishi, Yusuke, Tsumura, Akiko, Chandrashekran, Anil, Fenwick, Mark A, Tomaz, Rute A, Hosokawa, Hiroyuki, Nakayama, Toshinori, Chambers, Ian, Hiiragi, Takashi, Chazaud, Claire, Azuara, Véronique

“…The transcription factors Nanog and Gata6 are critical to specify the epiblast versus primitive endoderm (PrE) lineages. However, little is known about the…”
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Caspase-3, TUNEL and ultrastructural studies of small follicles in adult human ovarian biopsies by Hurst, Peter R., Mora, Jocelyn M., Fenwick, Mark A.

“…The aim of this study was to investigate evidence for cell death by apoptosis in small unilaminar ovarian follicles of adult humans. METHODS: Cortical biopsies…”
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Nuclear exclusion of SMAD2/3 in granulosa cells is associated with primordial follicle activation in the mouse ovary by Hardy, Kate, Mora, Jocelyn M, Dunlop, Carina, Carzaniga, Raffaella, Franks, Stephen, Fenwick, Mark A

“…Maintenance and activation of the limited supply of primordial follicles in the ovary are important determinants of reproductive lifespan. Currently, the…”
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The impact of endometrioma on in vitro fertilisation/intra-cytoplasmic injection IVF/ICSI reproductive outcomes: a systematic review and meta-analysis by Alshehre, Sallwa M., Narice, Brenda F., Fenwick, Mark A., Metwally, Mostafa

“…Background Assisted reproductive technologies (ART) such as in vitro fertilisation (IVF) and intra-cytoplasmic sperm injection (ICSI) are often used to aid…”
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Characterization and Significance of Adhesion and Junction-Related Proteins in Mouse Ovarian Follicles1 by Mora, Jocelyn M, Fenwick, Mark A, Castle, Laura, Baithun, Marianne, Ryder, Timothy A, Mobberley, Margaret, Carzaniga, Raffaella, Franks, Stephen, Hardy, Kate

“…In the ovary, initiation of follicle growth is marked by cuboidalization of flattened granulosa cells (GCs). The regulation and cell biology of this shape…”
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Negative energy balance alters global gene expression and immune responses in the uterus of postpartum dairy cows by Wathes, D. Claire, Cheng, Zhangrui, Chowdhury, Waliul, Fenwick, Mark A, Fitzpatrick, Richard, Morris, Dermot G, Patton, Joe, Murphy, John J

“…1 Reproduction Group, Department of Veterinary Basic Sciences, Royal Veterinary College, London, United Kingdom 2 Animal Production Research Centre, Mellows…”
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Characterization and Significance of Adhesion and Junction-Related Proteins in Mouse Ovarian Follicles by MORA, Jocelyn M, FENWICK, Mark A, CASTLE, Laura, BAITHUN, Marianne, RYDER, Timothy A, MOBBERLEY, Margaret, CARZANIGA, Raffaella, FRANKS, Stephen, HARDY, Kate

“…In the ovary, initiation of follicle growth is marked by cuboidalization of flattened granulosa cells (GCs). The regulation and cell biology of this shape…”
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Investigations of TGF-β Signaling in Preantral Follicles of Female Mice Reveal Differential Roles for Bone Morphogenetic Protein 15 by Fenwick, Mark A, Mora, Jocelyn M, Mansour, Yosef T, Baithun, Christina, Franks, Stephen, Hardy, Kate

“…Bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) are 2 closely related TGF-β ligands implicated as key regulators of follicle…”
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Identification and Regulation of Bone Morphogenetic Protein Antagonists Associated with Preantral Follicle Development in the Ovary by Fenwick, Mark A, Mansour, Yosef T, Franks, Stephen, Hardy, Kate

“…The TGFβ superfamily comprises several bone morphogenetic proteins (BMP) capable of exerting gonadotropin-independent effects on the development of small…”
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Serine threonine kinase receptor associated protein regulates early follicle development in the mouse ovary by Sharum, Isam B, Granados-Aparici, Sofia, Warrander, Fiona C, Tournant, Felicity P, Fenwick, Mark A

“…The molecular mechanisms involved in regulating the development of small, gonadotrophin-independent follicles are poorly understood; however, many studies have…”
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Influence of energy balance on the antimicrobial peptides S100A8 and S100A9 in the endometrium of the post-partum dairy cow by Swangchan-Uthai, Theerawat, Chen, Qiusheng, Kirton, Sally E, Fenwick, Mark A, Cheng, Zhangrui, Patton, Joe, Fouladi-Nashta, Ali A, Wathes, D Claire

“…Uterine inflammation occurs after calving in association with extensive endometrial remodelling and bacterial contamination. If the inflammation persists, it…”
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Suppression of Prolactin-Induced Signal Transducer and Activator of Transcription 5b Signaling and Induction of Suppressors of Cytokine Signaling Messenger Ribonucleic Acid in the Hypothalamic Arcuate Nucleus of the Rat during Late Pregnancy and Lactation by Anderson, Greg M, Beijer, Paulien, Bang, Angela S, Fenwick, Mark A, Bunn, Stephen J, Grattan, David R

“…During late pregnancy and lactation, the tuberoinfundibular dopamine (TIDA) neurons that regulate prolactin secretion by negative feedback become less able to…”
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Moderate Inhibition of Bone Morphogenetic Protein (BMP) Signaling Induces Rapid Growth of Cultured Preantral Follicles by Fenwick, Mark A., Franks, Stephen, Hardy, Kate

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Expression and Regulation of Bone Morphogenetic Protein (BMP) Antagonists in Mouse Preantral Follicles by Fenwick, Mark A., Mora, Jocelyn M., Franks, Stephen, Hardy, Kate

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