Search Results - "Fenutría, Rafael"
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The CD5 Ectodomain Interacts with Conserved Fungal Cell Wall Components and Protects from Zymosan-Induced Septic Shock-Like Syndrome
Published in Proceedings of the National Academy of Sciences - PNAS (03-02-2009)“…The CD5 lymphocyte surface receptor is a group B member of the ancient and highly conserved scavenger receptor cysteine-rich superfamily. CD5 is expressed on…”
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CD6 binds to pathogen-associated molecular patterns and protects from LPS-induced septic shock
Published in Proceedings of the National Academy of Sciences - PNAS (10-07-2007)“…CD6 is a lymphocyte receptor that belongs to the scavenger receptor cysteine-rich superfamily. Because some members of the scavenger receptor cysteine-rich…”
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Transgenic expression of soluble human CD5 enhances experimentally-induced autoimmune and anti-tumoral immune responses
Published in PloS one (15-01-2014)“…CD5 is a lymphoid-specific transmembrane glycoprotein constitutively expressed on thymocytes and mature T and B1a lymphocytes. Current data support the view…”
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The Lymphocyte Receptor CD6 Interacts with Syntenin-1, a Scaffolding Protein Containing PDZ Domains
Published in The Journal of immunology (1950) (01-08-2005)“…CD6 is a type I membrane glycoprotein expressed on thymocytes, mature T and B1a lymphocytes, and CNS cells. CD6 binds to activated leukocyte cell adhesion…”
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Role of CD5/CD5L interactions in the homeostasis of regulatory lymphocyte subpopulations and the control of autoimmune disorders
Published in Journal of translational medicine (23-11-2011)Get full text
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Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death
Published in Nature communications (05-12-2017)“…The risk of emerging pandemic influenza A viruses (IAVs) that approach the devastating 1918 strain motivates finding strain-specific host–pathogen mechanisms…”
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CDK4/6 Inhibition on Glucose and Pancreatic Beta Cell Homeostasis in Young and Aged Rats
Published in Molecular cancer research (01-11-2017)“…Genetic deletion of cyclin-dependent kinase 4 ( ) is associated with pancreatic beta cell loss and glucose dysregulation in rodents. Palbociclib, one of the…”
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CyTOF Profiling of Zika and Dengue Virus-Infected Human Peripheral Blood Mononuclear Cells Identifies Phenotypic Signatures of Monotype Subsets and Upregulation of the Interferon-Inducible Protein CD169
Published in mSphere (30-06-2021)“…Zika and dengue virus (ZIKV and DENV) are two flaviviruses responsible for important vector-borne emerging infectious diseases. While there have been multiple…”
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Osteoprotegerin and Denosumab Stimulate Human Beta Cell Proliferation through Inhibition of the Receptor Activator of NF-κB Ligand Pathway
Published in Cell metabolism (07-07-2015)“…Diabetes results from a reduction of pancreatic β-cells. Stimulating replication could normalize β-cell mass. However, adult human β-cells are recalcitrant to…”
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The dengue virus 4 component of NIAID’s tetravalent TV003 vaccine drives its innate immune signature
Published in Experimental biology and medicine (Maywood, N.J.) (01-12-2022)“…Annually, roughly 2.5 billion people are at risk for dengue virus (DENV) infection, and the incidence of infection has increased 30-fold since its discovery in…”
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Lactogens Prevent ER Stress-Induced ß-Cell Death and Diabetes
Published in Diabetes (New York, N.Y.) (01-07-2018)“…ER stress is highly relevant in the context of diabetes, as inducers of β cell death and dysfunction implicated in the disease - including proinflammatory…”
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The Role of PTHrP in Pancreatic Beta-Cells and Implications for Diabetes Pathophysiology and Treatment
Published in Clinical reviews in bone and mineral metabolism (01-09-2014)“…Diabetes is one of the fastest growing diseases worldwide, with an immense economic and health burden attached. It is now well accepted that a deficiency of…”
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LOSS OF RIP2 EXACERBATES MURINE EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS (129.16)
Published in The Journal of immunology (1950) (01-04-2007)“…Receptor interacting protein 2 (RIP2), a putative serine-threonine kinase, is a modulator of the activation of both innate and adaptive immune responses…”
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Transgenic Expression of Soluble Human CD5 Enhances Experimentally-Induced Autoimmune and Anti-Tumoral Immune Responses: e84895
Published in PloS one (01-01-2014)“…CD5 is a lymphoid-specific transmembrane glycoprotein constitutively expressed on thymocytes and mature T and B1a lymphocytes. Current data support the view…”
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Polymerized-type I collagen for the treatment of patients with rheumatoid arthritis. Effect of intramuscular administration in a double blind placebo-controlled clinical trial
Published in Clinical and experimental rheumatology (01-09-2006)“…To determine the efficacy, tolerance and safety of intramuscular injections of porcine type I collagen-PVP in patients with RA in a long term-therapy. The…”
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