Search Results - "Fentress, Sarah J."
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The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18
Published in PLoS pathogens (01-11-2012)“…Secretory polymorphic serine/threonine kinases control pathogenesis of Toxoplasma gondii in the mouse. Genetic studies show that the pseudokinase ROP5 is…”
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Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii
Published in PLoS pathogens (01-04-2013)“…IFN-γ activates cells to restrict intracellular pathogens by upregulating cellular effectors including the p65 family of guanylate-binding proteins (GBPs)…”
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Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse
Published in Proceedings of the National Academy of Sciences - PNAS (21-01-2014)“…The intracellular parasite Toxoplasma gondii enjoys a wide host range and is adept at surviving in both naive and activated macrophages. Previous studies have…”
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Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence
Published in Cell host & microbe (16-12-2010)“…Macrophages are specialized to detect and destroy intracellular microbes and yet a number of pathogens have evolved to exploit this hostile niche. Here we…”
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Circadian Gene Bmal1 Regulates Diurnal Oscillations of Ly6Chi Inflammatory Monocytes
Published in Science (American Association for the Advancement of Science) (27-09-2013)“…Like most organ systems in the body, several components of the immune system appear to be regulated in a diurnal manner. However, the cell populations…”
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Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes
Published in Science (American Association for the Advancement of Science) (27-09-2013)“…Circadian clocks have evolved to regulate physiologic and behavioral rhythms in anticipation of changes in the environment. Although the molecular clock is…”
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High‐throughput profiling and analysis of plant responses over time to abiotic stress
Published in Plant direct (01-10-2017)“…Sorghum (Sorghum bicolor (L.) Moench) is a rapidly growing, high‐biomass crop prized for abiotic stress tolerance. However, measuring genotype‐by‐environment…”
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Quantitative, Image-Based Phenotyping Methods Provide Insight into Spatial and Temporal Dimensions of Plant Disease
Published in Plant physiology (Bethesda) (01-10-2016)“…Plant disease symptoms exhibit complex spatial and temporal patterns that are challenging to quantify. Image-based phenotyping approaches enable…”
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The secreted kinase ROP18 defends Toxoplasma's border
Published in BioEssays (01-09-2011)“…Toxoplasma gondii is a highly successful parasite capable of infecting virtually all warm‐blooded animals by actively invading nucleated host cells and forming…”
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The arginine‐rich N‐terminal domain of ROP18 is necessary for vacuole targeting and virulence of Toxoplasma gondii
Published in Cellular microbiology (01-12-2012)“…Summary Toxoplasma gondii uses specialized secretory organelles called rhoptries to deliver virulence determinants into the host cell during parasite invasion…”
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Enhanced Detection of Multiply Phosphorylated Peptides and Identification of Their Sites of Modification
Published in Analytical chemistry (Washington) (17-09-2013)“…Phosphorylation is an important post-translational modification that rapidly mediates many cellular events. A key to understanding the dynamics of the…”
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Quantitative, Image-Based Phenotyping Methods Provide Insight into Spatial and Temporal Dimensions of Plant Disease1[OPEN]
Published in Plant physiology (Bethesda) (29-09-2016)“…Novel, image-based phenotyping methods enhance characterization of plant-pathogen interactions. Plant disease symptoms exhibit complex spatial and temporal…”
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The secreted kinase ROP18 defends Toxoplasma 's border
Published in BioEssays (01-09-2011)“…Abstract Toxoplasma gondii is a highly successful parasite capable of infecting virtually all warm‐blooded animals by actively invading nucleated host cells…”
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Circadian Gene Bmal1 Regulates Diurnal Oscillations of Ly6C hi Inflammatory Monocytes
Published in Science (American Association for the Advancement of Science) (27-09-2013)“…Diurnal Immunology Like most organ systems in the body, several components of the immune system appear to be regulated in a diurnal manner. However, the cell…”
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Circadian Gene Bmal1 Regulates Diurnal Oscillations of Ly6ChiInflammatory Monocytes
Published in Science (American Association for the Advancement of Science) (27-09-2013)“…Circadian clocks have evolved to regulate physiologic and behavioral rhythms in anticipation of changes in the environment. Although the molecular clock is…”
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High-throughput profiling and analysis of plant responses over time to abiotic stress
Published in Plant direct (01-10-2017)“…Not provided…”
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Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii: e1003320
Published in PLoS pathogens (01-04-2013)“…IFN-γ activates cells to restrict intracellular pathogens by upregulating cellular effectors including the p65 family of guanylate-binding proteins (GBPs)…”
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