Search Results - "Fenton, S."

EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals by Gore, A. C, Chappell, V. A, Fenton, S. E, Flaws, J. A, Nadal, A, Prins, G. S, Toppari, J, Zoeller, R. T

“…The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to the scientific community about how environmental endocrine-disrupting…”
Get full text

Advances in Biomaterials for Drug Delivery by Fenton, Owen S., Olafson, Katy N., Pillai, Padmini S., Mitchell, Michael J., Langer, Robert

“…Advances in biomaterials for drug delivery are enabling significant progress in biology and medicine. Multidisciplinary collaborations between physical…”
Get full text

Executive Summary to EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals by Gore, A. C, Chappell, V. A, Fenton, S. E, Flaws, J. A, Nadal, A, Prins, G. S, Toppari, J, Zoeller, R. T

“…This Executive Summary to the Endocrine Society's second Scientific Statement on environmental endocrine-disrupting chemicals (EDCs) provides a synthesis of…”
Get full text

Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy by Oberli, Matthias A, Reichmuth, Andreas M, Dorkin, J. Robert, Mitchell, Michael J, Fenton, Owen S, Jaklenec, Ana, Anderson, Daniel G, Langer, Robert, Blankschtein, Daniel

“…The induction of a strong cytotoxic T cell response is an important prerequisite for successful immunotherapy against many viral diseases and tumors…”
Get full text

Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs by Kaczmarek, James C., Patel, Asha K., Kauffman, Kevin J., Fenton, Owen S., Webber, Matthew J., Heartlein, Michael W., DeRosa, Frank, Anderson, Daniel G.

“…Therapeutic nucleic acids hold great promise for the treatment of disease but require vectors for safe and effective delivery. Synthetic nanoparticle vectors…”
Get full text

Optimization of a Degradable Polymer–Lipid Nanoparticle for Potent Systemic Delivery of mRNA to the Lung Endothelium and Immune Cells by Kaczmarek, James C, Kauffman, Kevin J, Fenton, Owen S, Sadtler, Kaitlyn, Patel, Asha K, Heartlein, Michael W, DeRosa, Frank, Anderson, Daniel G

“…mRNA therapeutics hold great potential for treating a variety of diseases through protein-replacement, immunomodulation, and gene editing. However, much like…”
Get full text

Synthesis and Biological Evaluation of Ionizable Lipid Materials for the In Vivo Delivery of Messenger RNA to B Lymphocytes by Fenton, Owen S., Kauffman, Kevin J., Kaczmarek, James C., McClellan, Rebecca L., Jhunjhunwala, Siddharth, Tibbitt, Mark W., Zeng, Manhao D., Appel, Eric A., Dorkin, Joseph R., Mir, Faryal F., Yang, Jung H., Oberli, Matthias A., Heartlein, Michael W., DeRosa, Frank, Langer, Robert, Anderson, Daniel G.

“…B lymphocytes regulate several aspects of immunity including antibody production, cytokine secretion, and T‐cell activation; moreover, B cell misregulation is…”
Get full text

How Should DSM-V Criteria for Schizophrenia Include Cognitive Impairment? by Keefe, Richard S. E., Fenton, Wayne S.

“…Neurocognitive impairment is considered a core component of schizophrenia and is increasingly under investigation as a potential treatment target. On average,…”
Get full text

Environmental Predictors of Diversity in Recent Planktonic Foraminifera as Recorded in Marine Sediments by Fenton, Isabel S, Pearson, Paul N, Dunkley Jones, Tom, Purvis, Andy

“…Global diversity patterns are thought to result from a combination of environmental and historical factors. This study tests the set of ecological and…”
Get full text

Concise Total Synthesis of (+)-Asperazine, (+)-Pestalazine A, and (+)-iso-Pestalazine A. Structure Revision of (+)-Pestalazine A by Loach, Richard P, Fenton, Owen S, Movassaghi, Mohammad

“…The concise, enantioselective total syntheses of (+)-asperazine (1), (+)-iso-pestalazine A (2), and (+)-pestalazine A (3) have been achieved by the development…”
Get full text

Cancer Incidence Among Canadian Kidney Transplant Recipients by Villeneuve, P. J., Schaubel, D. E., Fenton, S. S., Shepherd, F. A., Jiang, Y., Mao, Y.

“…A number of studies have observed increased cancer incidence rates among individuals who have received renal transplants. Generally, however, these studies…”
Get full text

C7-Derivatization of C3-Alkylindoles Including Tryptophans and Tryptamines by Loach, Richard P, Fenton, Owen S, Amaike, Kazuma, Siegel, Dustin S, Ozkal, Erhan, Movassaghi, Mohammad

“…A versatile strategy for C7-selective boronation of tryptophans, tryptamines, and 3-alkylindoles by way of a single-pot C2/C7-diboronation–C2-protodeboronation…”
Get full text

Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs by Fenton, Owen S., Kauffman, Kevin J., McClellan, Rebecca L., Kaczmarek, James C., Zeng, Manhao D., Andresen, Jason L., Rhym, Luke H., Heartlein, Michael W., DeRosa, Frank, Anderson, Daniel G.

“…RNAs are a promising class of therapeutics given their ability to regulate protein concentrations at the cellular level. Developing safe and effective…”
Get full text

The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis by Metsios, George S., Moe, R. H., van der Esch, M., van Zanten, J. J. C. S. Veldhuijzen, Fenton, S. A. M., Koutedakis, Y., Vitalis, P., Kennedy, N., Brodin, N., Bostrom, C., Swinnen, T. W., Tzika, K., Niedermann, K., Nikiphorou, E., Fragoulis, G. E., Vlieland, T. P. V. M., Van den Ende, C. H. M., Kitas, George D.

“…Cardiovascular disease (CVD) morbidity and mortality is highly prevalent in patients with rheumatoid arthritis (RA) with debilitating effects for the…”
Get full text

Diet and sleep health: a scoping review of intervention studies in adults by Burrows, T., Fenton, S., Duncan, M.

“…Background Recent research has demonstrated an association between dietary intake and sleep health that can influence chronic disease risk factors. A scoping…”
Get full text

The influence of sleep health on dietary intake: a systematic review and meta‐analysis of intervention studies by Fenton, S., Burrows, T. L., Skinner, J. A., Duncan, M. J.

“…Background Poor dietary intake increases disease risk, and poor sleep influences diet. This systematic review and meta‐analysis of intervention studies aimed…”
Get full text

The NIMH-MATRICS consensus statement on negative symptoms by Kirkpatrick, Brian, Fenton, Wayne S, Carpenter, Jr, William T, Marder, Stephen R

Get full text

Characterizing occupational radon exposure greater than 100 Bq/m3 in a highly exposed country by Brobbey, A., Rydz, E., Fenton, S., Demers, P. A., Ge, C. B., Peters, C. E.

“…Radon is an established lung carcinogen concentrating in indoor environments with importance for many workers worldwide. However, a systematic assessment of…”
Get full text

Poly(β‐amino ester)‐co‐poly(caprolactone) Terpolymers as Nonviral Vectors for mRNA Delivery In Vitro and In Vivo by Capasso Palmiero, Umberto, Kaczmarek, James C., Fenton, Owen S., Anderson, Daniel G.

“…The production of new proteins with messenger RNA (mRNA) has gained a broad interest due to its potential for addressing a wide range of diseases. Here, the…”
Get full text

Barriers and facilitators for physical activity in rheumatic and musculoskeletal disease: a European-based survey by Metsios, George S., Fenton, S. A. M., Tzika, K., Moe, R. H., Fragoulis, G. E., Vlieland, T. P. M. Vliet, Nikiphorou, E., Van den Ende, C. H. M., Fatouros, I., van der Esch, M., Niedermann, K., Stavropoulos-Kalinoglou, A., van Zanten, J. J. C. S. Veldhuijzen, Brodin, N., O’Brien, C. M., Koutedakis, Y., Kennedy, N., Swinnen, T. W., Bostrom, C., Kitas, G. D.

“…Physical activity (PA) is a key strategy for improving symptoms in people with rheumatic and musculoskeletal diseases (RMDs). The aim of this study was to…”
Get full text