Search Results - "Fennell, T.R"

Human exposure and internal dose assessments of acrylamide in food by Dybing, E., Farmer, P.B., Andersen, M., Fennell, T.R., Lalljie, S.P.D., Müller, D.J.G., Olin, S., Petersen, B.J., Schlatter, J., Scholz, G., Scimeca, J.A., Slimani, N., Törnqvist, M., Tuijtelaars, S., Verger, P.

“…This review provides a framework contributing to the risk assessment of acrylamide in food. It is based on the outcome of the ILSI Europe FOSIE process, a risk…”
Get full text

Attenuation of cocaine self-administration by chronic oral phendimetrazine in rhesus monkeys by Czoty, P.W, Blough, B.E, Fennell, T.R, Snyder, R.W, Nader, M.A

“…Highlights • Phendimetrazine (PDM) is a pro-drug for the amphetamine-like monoamine releaser phenmetrazine (PM). • Chronic oral PDM treatment decreased cocaine…”
Get full text

Association of Growth During Infancy with Neurodevelopment and Obesity in Children Born Very Preterm: The Environmental Influences on Child Health Outcomes Cohort by O'Shea, T. Michael, Jensen, Elizabeth T., Yi, Joe X., Lester, Barry, Aschner, Judy L., Stroustrup, Annemarie, Zhang, Xueying, McGrath, Monica, Sanderson, Keia, Joseph, Robert M., Singh, Rachana, Thompson, Amanda L., Hofheimer, Julie, Vohr, Betty, McGowan, Elisabeth, Santos, Hudson, Fry, Rebecca C., Smith, P.B., Hopkins, Johns, Jacobson, L.P., Catellier, D.J., Gershon, R., Cella, D., Parsons, P., Kurunthachalam, K., Fennell, T.R., Sumner, S.J., Du, X., O'Brien, B., Arora, M., Teitelbaum, S.L., Wright, R.O., Stapleton, H.M., Ferguson, P.L., Lee, J.Y., Snowden, J., Merhar, S., Lampland, A., Reynolds, A., Moore, P., Washburn, L., Carter, B., Pastyrnak, S., Neal, C., Smith, L., Helderman, J., Vaidya, R., Obeid, R., Rollins, C., Bear, K., Lenski, M., Singh, R., Msall, M., Frazier, J., Gogcu, S., Montgomery, A., Kuban, K., Douglass, L., Jara, H., Joseph, R.

“…To evaluate associations between change in weight z score after neonatal intensive care unit (NICU) discharge and neurodevelopmental outcomes and obesity at…”
Get full text

Acute intravenous exposure to silver nanoparticles during pregnancy induces particle size and vehicle dependent changes in vascular tissue contractility in Sprague Dawley rats by Vidanapathirana, A.K., Thompson, L.C., Herco, M., Odom, J., Sumner, S.J., Fennell, T.R., Brown, J.M., Wingard, C.J.

“…•Use of Silver nanoparticles (AgNP) raises safety concerns during pregnancy.•Pregnant rats were studied 24h post-exposure to acute intravenous…”
Get full text

A Physiologically Based Dosimetry Description of Acrylonitrile and Cyanoethylene Oxide in the Rat by Gargas, M.L., Andersen, M.E., Teo, S.K.O., Batra, R., Fennell, T.R., Kedderis, G.L.

“…The cytochrome P450-mediated oxidation of acrylonitrile (ACN) to the mutagen 2-cyanoethylene oxide (CEO) is thought to be important for the carcinogenic…”
Get full text

C.6 - CHRONIC PHENDIMETRAZINE TREATMENT REDUCES COCAINE VS. FOOD CHOICE AND EXTENDED-ACCESS COCAINE CONSUMPTION BY RHESUS MONKEYS by Negus, S.S., Banks, M.L., Blough, B.E., Fennell, T.R., Snyder, R.W.

Get full text

Dose-dependent urinary excretion of acrylonitrile metabolites by rats and mice by Kedderis, G L, Sumner, S C, Held, S D, Batra, R, Turner, Jr, M J, Roberts, A E, Fennell, T R

“…The dose dependence of the urinary excretion of acrylonitrile (ACN) metabolites was studied after oral administration of [2,3-14C]ACN to male F-344 rats (0.09…”
Get more information

Opportunities for examining child health impacts of early-life nutrition in the ECHO Program: Maternal and child dietary intake data from pregnancy to adolescence by Alshawabkeh, Akram N., Camargo, Carlos A., Catellier, Diane J., Comstock, Sarah S., Dunlop, Anne L., Hedderson, Monique M., Hockett, Christine W., Karagas, Margaret R., Keenan, Kate, Kelly, Nichole R., Kerver, Jean M., Mahabir, Somdat, Melough, Melissa M., Mueller, Noel T., Nelson, Morgan E., O’Connor, Thomas G., Oken, Emily, Lyall, Kristen, Merhar, S., Lampland, A., Washburn, L., Trasande, L., Laham, F.R., Wu, S., Celedón, J.C., Puls, H.T., Teach, S.J., Iyer, S.S., Samuels-Kalow, M.E., Thompson, A.D., Stevenson, M.D., Bauer, C.S., Inhofe, N.R., Macias, C.G., Deoni, S., Duarte, C.S., Herbstman, J., Gern, J., Miller, R., Seroogy, C., Jackson, D., O’Connor, G., Kattan, M., Rivera-Spoljaric, K., Gold, D., Johnson, C., Breton, C., Bastain, T., Hertz-Picciotto, I., Hipwell, A., Karr, C., LeWinn, K.Z., Barrett, E., Swan, S., Mason, A., Lester, B., Carter, B., Smith, L., Helderman, J., Leve, L., Ganiban, J., Lewis, J., Weiss, S.T., O’Connor, G., McEvoy, C., Volk, H., Ozonoff, S., Schmidt, R., Dager, S., Schultz, R., Simhan, H., Singh, R., Msall, M., Frazier, J., Gogcu, S., Kuban, K., Douglass, L., Joseph, R., Fussman, C., Paneth, N., Ruden, D., Schantz, S., Woodruff, T., Stanford, J., Porucznik, C., Giardino, A., Innocenti, M., Silver, R., Conradt, E., Wright, R.J., Wright, R.O., Bosquet-Enlow, M., Newby, L.K., Jacobson, L.P., Gershon, R., Kurunthachalam, K., Sumner, S.J., O'Brien, B., Teitelbaum, S.L., Stapleton, H.M.

“…Longitudinal measures of diet spanning pregnancy through adolescence are needed from a large, diverse sample to advance research on the effect of early-life…”
Get full text

Dose Effects on the Excretion of Urinary Metabolites of 2-[1,2,methoxy-13C]Methoxyethanol in Rats and Mice by Sumner, S.J., Stedman, D.B., Cheng, S.Y., Welsch, F., Fennell, T.R.

“…The administration of 2-methoxyethanol (2-ME) to pregnant rats, mice, or primates results in developmental toxicity. To assess the role of metabolism in the…”
Get full text

A critical review of the toxicology of glutaraldehyde by Beauchamp, Jr, R O, St Clair, M B, Fennell, T R, Clarke, D O, Morgan, K T, Kari, F W

“…Glutaraldehyde, a low molecular weight aldehyde, has been investigated for toxicity in humans and animals. Examination of this dialdehyde was indicated from…”
Get more information

Characterization of phosphodiester adducts produced by the reaction of cyanoethylene oxide with nucleotides by Yates, J M, Fennell, T R, Turner, Jr, M J, Recio, L, Sumner, S C

“…Cyanoethylene oxide (CEO), a putative toxic and carcinogenic metabolite of acrylonitrile, is a direct-acting mutagen. The focus of this study was to elucidate…”
Get more information

A physiologically based description of ethylene oxide dosimetry in the rat by Krishnan, K, Gargas, M L, Fennell, T R, Andersen, M E

“…A physiologically based pharmacokinetic (PB-PK) model providing a quantitative description of ethylene oxide (ETO) dosimetry in the rat was developed by…”
Get more information

Reconsideration of the genetic risk assessment for ethylene oxide exposures by Preston, R J, Fennell, T R, Leber, A P, Sielken, Jr, R L, Swenberg, J A

“…The US Environmental Protection Agency (EPA) developed a genetic risk assessment model for exposures to ethylene oxide utilizing data on the induction of…”
Get more information

Characterization of an adduct and its degradation product produced by the reaction of cyanoethylene oxide with deoxythymidine and DNA by Yates, J M, Summer, S C, Turner, Jr, M J, Recio, L, Fennell, T R

“…Cyanoethylene oxide (CEO), the putative toxic and carcinogenic metabolite of acrylonitrile, is a direct-acting mutagen. CEO reacted with deoxythymidine (dT) to…”
Get more information

The induction of hepatic cytochrome P-450 in C57 BL/10 and DBA/2 mice by isosafrole and piperonyl butoxide. A comparative study with other inducing agents by Fennell, T R, Sweatman, B C, Bridges, J W

“…The formation of cytochrome P-450 metabolite complexes with isosafrole and piperonyl butoxide in vivo in genetically 'responsive' C57 BL/10 mice and…”
Get more information