Search Results - "Fennell, R"

High-throughput human primary cell-based airway model for evaluating influenza, coronavirus, or other respiratory viruses in vitro by Gard, A. L., Luu, R. J., Miller, C. R., Maloney, R., Cain, B. P., Marr, E. E., Burns, D. M., Gaibler, R., Mulhern, T. J., Wong, C. A., Alladina, J., Coppeta, J. R., Liu, P., Wang, J. P., Azizgolshani, H., Fezzie, R. Fennell, Balestrini, J. L., Isenberg, B. C., Medoff, B. D., Finberg, R. W., Borenstein, J. T.

“…Influenza and other respiratory viruses present a significant threat to public health, national security, and the world economy, and can lead to the emergence…”
Get full text

Alpha band oscillations in common synaptic input are explanatory of the complexity of isometric knee extensor muscle torque signals by Fennell, Christopher R. J., Mauger, Alexis R., Hopker, James G.

“…We investigated whether the strength of oscillations in common synaptic input was explanatory of knee extensor (KE) torque signal complexity during fresh and…”
Get full text

Inter-day reliability of heart rate complexity and variability metrics in healthy highly active younger and older adults by Fennell, Christopher R. J., Mauger, Alexis R., Hopker, James G.

“…Purpose To investigate the inter-day reliability of time-domain, frequency-domain, and nonlinear HRV metrics in healthy highly active younger and older adults…”
Get full text

The acute physiological and perceptual effects of recovery interval intensity during cycling-based high-intensity interval training by Fennell, Christopher R. J., Hopker, James G.

“…Purpose The current study sought to investigate the role of recovery intensity on the physiological and perceptual responses during cycling-based aerobic…”
Get full text

The use of dried blood spots for characterizing children's exposure to organic environmental chemicals by Barr, Dana Boyd, Kannan, Kurunthachalam, Cui, Yuxia, Merrill, Lori, Petrick, Lauren M., Meeker, John D., Fennell, Timothy R., Faustman, Elaine M.

“…Biomonitoring is a commonly used tool for exposure assessment of organic environmental chemicals with urine and blood samples being the most commonly used…”
Get full text

Oral administration of TiO2 nanoparticles during early life impacts cardiac and neurobehavioral performance and metabolite profile in an age- and sex-related manner by Mortensen, Ninell P, Pathmasiri, Wimal, Snyder, Rodney W, Caffaro, Maria Moreno, Watson, Scott L, Patel, Purvi R, Beeravalli, Lakshmi, Prattipati, Sharmista, Aravamudhan, Shyam, Sumner, Susan J, Fennell, Timothy R

“…Abstract Background Nanoparticles (NPs) are increasingly incorporated in everyday products. To investigate the effects of early life exposure to orally…”
Get full text

In vitro and in vivo pharmacokinetics and metabolism of synthetic cannabinoids CUMYL-PICA and 5F-CUMYL-PICA by Kevin, Richard C., Lefever, Timothy W., Snyder, Rodney W., Patel, Purvi R., Fennell, Timothy R., Wiley, Jenny L., McGregor, Iain S., Thomas, Brian F.

“…CUMYL-PICA [1-pentyl- N -(2-phenylpropan-2-yl)-1 H -indole-3-carboxamide] and 5F-CUMYL-PICA [1-(5-fluoropentyl)- N -(2-phenylpropan-2-yl)-1 H…”
Get full text

A Metabolomics Approach to Investigate Kukoamine B-A Potent Natural Product With Anti-diabetic Properties by Li, Yuan-Yuan, Stewart, Delisha A, Ye, Xiao-Min, Yin, Li-Hua, Pathmasiri, Wimal W, McRitchie, Susan L, Fennell, Timothy R, Cheung, Hon-Yeung, Sumner, Susan J

“…Due to the surge in type 2 diabetes mellitus (T2DM), treatments for chronic metabolic dysregulations with fewer side-effects are sought. Lycii Cortex (LyC), a…”
Get full text

Metabolism and Hemoglobin Adduct Formation of Acrylamide in Humans by Fennell, Timothy R., Sumner, Susan C.J., Snyder, Rodney W., Burgess, Jason, Spicer, Rebecca, Bridson, William E., Friedman, Marvin A.

“…Acrylamide (AM), used in the manufacture of polyacrylamide and grouting agents, is produced during the cooking of foods. Workplace exposure to AM can occur…”
Get full text

Sex Differences in the Effects of a Kappa Opioid Receptor Antagonist in the Forced Swim Test by Laman-Maharg, Abigail, Williams, Alexia V, Zufelt, Mikaela D, Minie, Vanessa A, Ramos-Maciel, Stephanie, Hao, Rebecca, Ordoñes Sanchez, Evelyn, Copeland, Tiffany, Silverman, Jill L, Leigh, Angelina, Snyder, Rodney, Carroll, F Ivy, Fennell, Timothy R, Trainor, Brian C

“…There is growing evidence that kappa opioid receptor (KOR) antagonists could be a useful class of therapeutics for treating depression and anxiety. However,…”
Get full text

Role of CYP2E1 in the Epoxidation of Acrylamide to Glycidamide and Formation of DNA and Hemoglobin Adducts by Ghanayem, Burhan I., McDaniel, L. Patrice, Churchwell, Mona I., Twaddle, Nathan C., Snyder, Rodney, Fennell, Timothy R., Doerge, Daniel R.

“…Acrylamide (AA) is an animal carcinogen, neurotoxin, and reproductive toxin. AA is formed in baked and fried carbohydrate-rich foods. Metabolism of AA occurs…”
Get full text

Distribution of carbon-14 labeled C60 ([14C]C60) in the pregnant and in the lactating dam and the effect of C60 exposure on the biochemical profile of urine by Sumner, Susan C. J., Fennell, Timothy R., Snyder, Rodney W., Taylor, George F., Lewin, Anita H.

“…This study was conducted to determine the distribution of [14C]C60 in the pregnant rat and fetuses, and in the lactating rat and offspring. Pregnant rats were…”
Get full text

Human exposure and internal dose assessments of acrylamide in food by Dybing, E., Farmer, P.B., Andersen, M., Fennell, T.R., Lalljie, S.P.D., Müller, D.J.G., Olin, S., Petersen, B.J., Schlatter, J., Scholz, G., Scimeca, J.A., Slimani, N., Törnqvist, M., Tuijtelaars, S., Verger, P.

“…This review provides a framework contributing to the risk assessment of acrylamide in food. It is based on the outcome of the ILSI Europe FOSIE process, a risk…”
Get full text

The Acute Physiological and Perceptual Effects of Individualizing the Recovery Interval Duration Based Upon the Resolution of Muscle Oxygen Consumption During Cycling Exercise by Fennell, Christopher R J, Hopker, James G

“…There has been paucity in research investigating the individualization of recovery interval duration during cycling-based high-intensity interval training…”
Get more information

Role of Cytochrome P450 2E1 in the Metabolism of Acrylamide and Acrylonitrile in Mice by Sumner, Susan C. J, Fennell, Timothy R, Moore, Timothy A, Chanas, Brian, Gonzalez, Frank, Ghanayem, Burhan I

“…Acrylonitrile (AN) and acrylamide (AM) are commonly used in the synthesis of plastics and polymers. In rodents, AM and AN are metabolized to the epoxides…”
Get full text

Attenuation of cocaine self-administration by chronic oral phendimetrazine in rhesus monkeys by Czoty, P.W, Blough, B.E, Fennell, T.R, Snyder, R.W, Nader, M.A

“…Highlights • Phendimetrazine (PDM) is a pro-drug for the amphetamine-like monoamine releaser phenmetrazine (PM). • Chronic oral PDM treatment decreased cocaine…”
Get full text

Investigation of the Low-Dose Response in the In Vivo Induction of Micronuclei and Adducts by Acrylamide by Zeiger, Errol, Recio, Leslie, Fennell, Timothy R., Haseman, Joseph K., Snyder, Rodney W., Friedman, Marvin

“…Acrylamide is an industrial chemical used in polymer manufacture. It is also formed in foods processed at high temperatures. It induces chromosome aberrations…”
Get full text

Kinetics of Elimination of Urinary Metabolites of Acrylamide in Humans by Fennell, Timothy R., Sumner, Susan C. J., Snyder, Rodney W., Burgess, Jason, Friedman, Marvin A.

“…Acrylamide (AM), used in the manufacture of polyacrylamide and grouting agents, is produced during the cooking of foods. Workplace exposure to AM can occur…”
Get full text

Simulated Gastric Digestion and In Vivo Intestinal Uptake of Orally Administered CuO Nanoparticles and TiO2 E171 in Male and Female Rat Pups by Mortensen, Ninell P., Moreno Caffaro, Maria, Aravamudhan, Shyam, Beeravalli, Lakshmi, Prattipati, Sharmista, Snyder, Rodney W., Watson, Scott L., Patel, Purvi R., Weber, Frank X., Montgomery, Stephanie A., Sumner, Susan J., Fennell, Timothy R.

“…Oral exposure to nanoparticles (NPs) during early life is an understudied area. The goals of this study were to evaluate the effect of pre-weaned rat gastric…”
Get full text

Metabolism and Disposition of Bisphenol A in Female Rats by Snyder, Rodney W., Maness, Susan C., Gaido, Kevin W., Welsch, Frank, Sumner, Susan C.J., Fennell, Timothy R.

“…Bisphenol A (BPA), which is used in the manufacture of polycarbonates, elicits weak estrogenic activity in in vitro and in vivo test systems. The objectives of…”
Get full text