Search Results - "Fennell, Katie A"

Non-genetic determinants of malignant clonal fitness at single-cell resolution by Fennell, Katie A., Vassiliadis, Dane, Lam, Enid Y. N., Martelotto, Luciano G., Balic, Jesse J., Hollizeck, Sebastian, Weber, Tom S., Semple, Timothy, Wang, Qing, Miles, Denise C., MacPherson, Laura, Chan, Yih-Chih, Guirguis, Andrew A., Kats, Lev M., Wong, Emily S., Dawson, Sarah-Jane, Naik, Shalin H., Dawson, Mark A.

“…All cancers emerge after a period of clonal selection and subsequent clonal expansion. Although the evolutionary principles imparted by genetic intratumour…”
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Epigenetic therapies in acute myeloid leukemia: where to from here? by Fennell, Katie A., Bell, Charles C., Dawson, Mark A.

“…A hallmark of acute myeloid leukemia (AML) is epigenetic dysregulation, which is initiated by recurrent translocations and/or mutations in transcription…”
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Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia by Bell, Charles C., Fennell, Katie A., Chan, Yih-Chih, Rambow, Florian, Yeung, Miriam M., Vassiliadis, Dane, Lara, Luis, Yeh, Paul, Martelotto, Luciano G., Rogiers, Aljosja, Kremer, Brandon E., Barbash, Olena, Mohammad, Helai P., Johanson, Timothy M., Burr, Marian L., Dhar, Arindam, Karpinich, Natalie, Tian, Luyi, Tyler, Dean S., MacPherson, Laura, Shi, Junwei, Pinnawala, Nathan, Yew Fong, Chun, Papenfuss, Anthony T., Grimmond, Sean M., Dawson, Sarah-Jane, Allan, Rhys S., Kruger, Ryan G., Vakoc, Christopher R., Goode, David L., Naik, Shalin H., Gilan, Omer, Lam, Enid Y. N., Marine, Jean-Christophe, Prinjha, Rab K., Dawson, Mark A.

“…Non-genetic drug resistance is increasingly recognised in various cancers. Molecular insights into this process are lacking and it is unknown whether stable…”
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Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses by Chan, Kah Lok, Gomez, Juliana, Cardinez, Chelisa, Kumari, Nishi, Sparbier, Christina E., Lam, Enid Y.N., Yeung, Miriam M., Garciaz, Sylvain, Kuzich, James A., Ong, Doen Ming, Brown, Fiona C., Chan, Yih-Chih, Vassiliadis, Dane, Wainwright, Elanor N., Motazedian, Ali, Gillespie, Andrea, Fennell, Katie A., Lai, Junyun, House, Imran G., Macpherson, Laura, Ang, Ching-Seng, Dawson, Sarah-Jane, Beavis, Paul A., Wei, Andrew H., Burr, Marian L., Dawson, Mark A.

“…There is increasing recognition of the prognostic significance of tumor cell major histocompatibility complex (MHC) class II expression in anti-cancer…”
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SPOP tips the balance of BETs in cancer by Fennell, Katie A, Dawson, Mark A

“…Cancer-associated mutations in speckle-type POZ (pox virus and zinc-finger) protein confer neomorphic activity, altering its substrate affinities and its…”
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Analysis of synthetic cellular barcodes in the genome and transcriptome with BARtab and bartools by Holze, Henrietta, Talarmain, Laure, Fennell, Katie A., Lam, Enid Y., Dawson, Mark A., Vassiliadis, Dane

“…Cellular barcoding is a lineage-tracing methodology that couples heritable synthetic barcodes to high-throughput sequencing, enabling the accurate tracing of…”
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Clonal analysis of fetal hematopoietic stem/progenitor cells reveals how post-transplantation capabilities are distributed by Stonehouse, Olivia J., Biben, Christine, Weber, Tom S., Garnham, Alexandra, Fennell, Katie A., Farley, Alison, Terreaux, Antoine F., Alexander, Warren S., Dawson, Mark A., Naik, Shalin H., Taoudi, Samir

“…It has been proposed that adult hematopoiesis is sustained by multipotent progenitors (MPPs) specified during embryogenesis. Adult-like hematopoietic stem cell…”
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