Search Results - "Feng, Yukuan"

microRNA-128 plays a critical role in human non-small cell lung cancer tumourigenesis, angiogenesis and lymphangiogenesis by directly targeting vascular endothelial growth factor-C by Hu, Jing, Cheng, Yongxia, Li, Yuezhen, Jin, Zaishun, Pan, Yanming, Liu, Guibo, Fu, Songbin, Zhang, Yafang, Feng, Kejian, Feng, Yukuan

“…Abstract Recent studies have indicated that microRNAs (miRNAs) are important gene regulators that play critical roles in biological processes and function as…”
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Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases by Wang, Yumin, Hu, Jing, Wu, Shuang, Fleishman, Joshua S., Li, Yulin, Xu, Yinshi, Zou, Wailong, Wang, Jinhua, Feng, Yukuan, Chen, Jichao, Wang, Hongquan

“…Ferroptosis, a unique modality of cell death with mechanistic and morphological differences from other cell death modes, plays a pivotal role in regulating…”
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MiR-215 Is Induced Post-transcriptionally via HIF-Drosha Complex and Mediates Glioma-Initiating Cell Adaptation to Hypoxia by Targeting KDM1B by Hu, Jing, Sun, Tao, Wang, Hui, Chen, Zhengxin, Wang, Shuai, Yuan, Lifeng, Liu, Tingyu, Li, Hai-Ri, Wang, Pingping, Feng, Yukuan, Wang, Qinhong, McLendon, Roger E., Friedman, Allan H., Keir, Stephen T., Bigner, Darell D., Rathmell, Jeff, Fu, Xiang-dong, Li, Qi-Jing, Wang, Huibo, Wang, Xiao-Fan

“…The hypoxic tumor microenvironment serves as a niche for maintaining the glioma-initiating cells (GICs) that are critical for glioblastoma (GBM) occurrence and…”
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Inducing ferroptosis by traditional medicines: a novel approach to reverse chemoresistance in lung cancer by Wang, Yumin, Hu, Jing, Fleishman, Joshua S, Li, Yulin, Ren, Zhao, Wang, Jinhua, Feng, Yukuan, Chen, Jichao, Wang, Hongquan

“…Lung cancer is the leading cause of global cancer-related deaths. Platinum-based chemotherapy is the first-line treatment for the most common type of lung…”
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miRNA-556-3p promotes human bladder cancer proliferation, migration and invasion by negatively regulating DAB2IP expression by Feng, Chen, Sun, Ping, Hu, Jing, Feng, Hua, Li, Mingqiu, Liu, Guibo, Pan, Yanming, Feng, Ying, Xu, Yongliang, Feng, Kejian, Feng, Yukuan

“…MicroRNAs (miRNAs) play critical roles in tumorigenesis and metastasis by negatively regulating gene expression through complementary binding to the…”
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Combination of RUNX1 inhibitor and gemcitabine mitigates chemo-resistance in pancreatic ductal adenocarcinoma by modulating BiP/PERK/eIF2α-axis-mediated endoplasmic reticulum stress by She, Chunhua, Wu, Chao, Guo, Weihua, Xie, Yongjie, Li, Shouyi, Liu, Weishuai, Xu, Chao, Li, Hui, Cao, Pei, Yang, Yanfang, Wang, Xiuchao, Chang, Antao, Feng, Yukuan, Hao, Jihui

“…Gemcitabine (GEM)-based chemotherapy is the first-line option for pancreatic ductal adenocarcinoma (PDAC). However, the development of drug resistance limits…”
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RNAi-mediated silencing of VEGF-C inhibits non-small cell lung cancer progression by simultaneously down-regulating the CXCR4, CCR7, VEGFR-2 and VEGFR-3-dependent axes-induced ERK, p38 and AKT signalling pathways by Feng, Yukuan, Hu, Jing, Ma, Jing, Feng, Kejian, Zhang, Xiaoli, Yang, Shucai, Wang, Wei, Zhang, Jianguo, Zhang, Yafang

“…Abstract Vascular endothelial growth factor C (VEGF-C) expression is associated with the malignant tumour phenotype making it an attractive therapeutic target…”
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mTORC1-c-Myc pathway rewires methionine metabolism for HCC progression through suppressing SIRT4 mediated ADP ribosylation of MAT2A by Zhao, Liang, Su, Huizhao, Liu, Xiaomeng, Wang, Hongquan, Feng, Yukuan, Wang, Yan, Chen, Haiqiang, Dai, Luo, Lai, Shihui, Xu, Siqi, Li, Chong, Hao, Jihui, Tang, Bo

“…Abstract Background Exploiting cancer metabolism during nutrient availability holds immense potential for the clinical and therapeutic benefits of…”
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Retraction Note: LNCAROD enhances hepatocellular carcinoma malignancy by activating glycolysis through induction of pyruvate kinase isoform PKM2 by Jia, Guizhi, Wang, Yan, Lin, Chengjie, Lai, Shihui, Dai, Hongliang, Wang, Zhiqian, Dai, Luo, Su, Huizhao, Song, Yanjie, Zhang, Naiwen, Feng, Yukuan, Tang, Bo

“…This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-021-02090-7…”
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Embryonic germ cell extracts erase imprinted genes and improve the efficiency of induced pluripotent stem cells by Hu, Jing, Zhao, Qiaoshi, Feng, Yukuan, Li, Na, Gu, Yanli, Sun, Ruizhen, Duan, Lian, Wu, Yanshuang, Shan, Zhiyan, Lei, Lei

“…Patient-specific induced pluripotent stem cells (iPSCs) have the potential to be useful in the treatment of human diseases. While prior studies have reported…”
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RETRACTED ARTICLE: LNCAROD enhances hepatocellular carcinoma malignancy by activating glycolysis through induction of pyruvate kinase isoform PKM2 by Jia, Guizhi, Wang, Yan, Lin, Chengjie, Lai, Shihui, Dai, Hongliang, Wang, Zhiqian, Dai, Luo, Su, Huizhao, Song, Yanjie, Zhang, Naiwen, Feng, Yukuan, Tang, Bo

“…Abstract Background Mounting evidence has suggested the essential role of long non-coding RNAs (lncRNAs) in a plethora of malignant tumors, including…”
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Lentivirus-Mediated RNAi Knockdown of NUPR1 Inhibits Human Nonsmall Cell Lung Cancer Growth In Vitro and In Vivo by Guo, Xiaotong, Wang, Wei, Hu, Jing, Feng, Kejian, Pan, Yanming, Zhang, Linyou, Feng, Yukuan

“…NUPR1 (nuclear protein 1) was found to play a key role in the development of several malignancies including pancreas, breast, and prostate cancers. However,…”
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Nuclear PLD1 combined with NPM1 induces gemcitabine resistance through tumorigenic IL7R in pancreatic adenocarcinoma by Fu, Danqi, Yan, Jingrui, Zhang, Zhaoyu, Liu, Yang, Ma, Xiaoqing, Ding, Jinsheng, Yang, Shengyu, Zhao, Ran, Chang, Antao, Gao, Chuntao, Liu, Jing, Zhao, Tiansuo, Wang, Xiuchao, Huang, Chongbiao, Gao, Song, Ma, Ying, Tang, Bo, Feng, Yukuan, Wang, Hongwei, Hao, Jihui

“…Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant gastrointestinal cancer with a 5-year survival rate of only 9%. Of PDAC patients, 15%-20% are…”
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Hypoxia-Induced LIN28A mRNA Promotes the Metastasis of Colon Cancer in a Protein-Coding-Independent Manner by Weng, Mingjiao, Feng, Yukuan, He, Yan, Yang, Weiwei, Li, Jing, Zhu, Yuanyuan, Wang, Tianzhen, Wang, Chuhan, Zhang, Xiao, Qiao, Yu, Li, Qi, Zhao, Lingyu, Gao, Shuangshu, Zhang, Lei, Wu, Yiqi, Zhao, Ran, Wang, Guangyu, Li, Zhiwei, Jin, Xiaoming, Zheng, Tongsen, Li, Xiaobo

“…The hypoxic microenvironment is beneficial to the metastasis but not to the proliferation of cancer cells. However, the mechanisms regarding to hypoxia…”
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Brain Metastases in Women With Epithelial Ovarian Cancer: Multimodal Treatment Including Surgery or Gamma-Knife Radiation Is Associated With Prolonged Survival by Niu, Xiaoyu, MD, Rajanbabu, Anupama, MD, MRCOG, Delisle, Megan, DEC, Peng, Feng, MD, PhD, Vijaykumar, Dehannathuparambil K., MS, MCh, Pavithran, Keechilattu, MD, DM, Feng, Yukuan, MD, Lau, Susie, MD, MSc, FRCSC, Gotlieb, Walter H., MD, PhD, Press, Joshua Z., MD, MSc, FRCSC

“…Abstract Objective To explore the impact of treatment modality on survival in patients with brain metastases from epithelial ovarian cancer. Methods We…”
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LNCAROD enhances hepatocellular carcinoma malignancy by activating glycolysis through induction of pyruvate kinase isoform PKM2 by Jia, Guizhi, Wang, Yan, Lin, Chengjie, Lai, Shihui, Dai, Hongliang, Wang, Zhiqian, Dai, Luo, Su, Huizhao, Song, Yanjie, Zhang, Naiwen, Feng, Yukuan, Tang, Bo

“…Mounting evidence has suggested the essential role of long non-coding RNAs (lncRNAs) in a plethora of malignant tumors, including hepatocellular carcinoma…”
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Beyond a chemopreventive reagent, aspirin is a master regulator of the hallmarks of cancer by Zhang, Xiao, Feng, Yukuan, Liu, Xi, Ma, Jianhui, Li, Yafei, Wang, Tianzhen, Li, Xiaobo

“…Purpose Aspirin, one of the most commonly used nonsteroidal anti-inflammatory drugs (NAIDS), not only shows cancer chemoprevention effects but also improves…”
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Tumor-derived interleukin 35 mediates the dissemination of gemcitabine resistance in pancreatic adenocarcinoma by Sun, Huizhi, Ge, Yi, Liu, Jing, Li, Zengxun, Li, Hui, Zhao, Tiansuo, Wang, Xiuchao, Feng, Yukuan, Wang, Hongwei, Gao, Song, Shi, Lei, Yang, Shengyu, Sun, Peiqing, Chang, Antao, Hao, Jihui, Huang, Chongbiao

“…Rapid development of drug resistance after chemotherapy is a major cause of treatment failure in individuals with pancreatic ductal adenocarcinoma (PDAC). In…”
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Combination of RUNX1 inhibitor and gemcitabine mitigates chemo-resistance in pancreatic ductal adenocarcinoma by modulating BiP/PERK/eIF2[alpha]-axis-mediated endoplasmic reticulum stress by She, Chunhua, Wu, Chao, Guo, Weihua, Xie, Yongjie, Li, Shouyi, Liu, Weishuai, Xu, Chao, Li, Hui, Cao, Pei, Yang, Yanfang, Wang, Xiuchao, Chang, Antao, Feng, Yukuan, Hao, Jihui

“…Background Gemcitabine (GEM)-based chemotherapy is the first-line option for pancreatic ductal adenocarcinoma (PDAC). However, the development of drug…”
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miRNA-223 inhibits epithelial-mesenchymal transition in gastric carcinoma cells via Sp1 by HU, JING, SHAN, ZHIYAN, HU, KEWEI, REN, FENGYUN, ZHANG, WEI, HAN, MEILING, LI, YUEZHEN, FENG, KEJIAN, LEI, LEI, FENG, YUKUAN

“…Sp1 plays critical roles in epithelial-mesenchymal transition (EMT) of certain cancer. However, few studies have indicated whether Sp1 is involved in the EMT…”
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