Search Results - "Feng, Wenyi"

Exceptional origin activation revealed by comparative analysis in two laboratory yeast strains by Joshi, Ishita, Peng, Jie, Alvino, Gina, Kwan, Elizabeth, Feng, Wenyi

“…We performed a comparative analysis of replication origin activation by genome-wide single-stranded DNA mapping in two yeast strains challenged by hydroxyurea,…”
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R-loops at centromeric chromatin contribute to defects in kinetochore integrity and chromosomal instability in budding yeast by Mishra, Prashant K, Chakraborty, Arijita, Yeh, Elaine, Feng, Wenyi, Bloom, Kerry S, Basrai, Munira A

“…R-loops, the byproduct of DNA-RNA hybridization and the displaced single-stranded DNA (ssDNA), have been identified in bacteria, yeasts, and other eukaryotic…”
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Break-seq reveals hydroxyurea-induced chromosome fragility as a result of unscheduled conflict between DNA replication and transcription by Hoffman, Elizabeth A, McCulley, Andrew, Haarer, Brian, Arnak, Remigiusz, Feng, Wenyi

“…We have previously demonstrated that in Saccharomyces cerevisiae replication, checkpoint inactivation via a mec1 mutation leads to chromosome breakage at…”
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The yeast Dbf4 Zn2+ finger domain suppresses single-stranded DNA at replication forks initiated from a subset of origins by Bachant, Jeff, Hoffman, Elizabeth A., Caridi, Chris, Nugent, Constance I., Feng, Wenyi

“…Dbf4 is the cyclin-like subunit for the Dbf4-dependent protein kinase (DDK), required for activating the replicative helicase at DNA replication origin that…”
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Yeast Stn1 promotes MCM to circumvent Rad53 control of the S phase checkpoint by Gasparayan, Hovik, Caridi, Chris, Julius, Jeff, Feng, Wenyi, Bachant, Jeff, Nugent, Constance I.

“…Treating yeast cells with the replication inhibitor hydroxyurea activates the S phase checkpoint kinase Rad53, eliciting responses that block DNA replication…”
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Replication Stress Induces Global Chromosome Breakage in the Fragile X Genome by Chakraborty, Arijita, Jenjaroenpun, Piroon, Li, Jing, El Hilali, Sami, McCulley, Andrew, Haarer, Brian, Hoffman, Elizabeth A., Belak, Aimee, Thorland, Audrey, Hehnly, Heidi, Schildkraut, Carl L., Chen, Chun-long, Kuznetsov, Vladimir A., Feng, Wenyi

“…Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by mutations in the FMR1 gene and deficiency of a functional FMRP protein. FMRP is known as a…”
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Epigenomic signatures associated with spontaneous and replication stress-induced DNA double strand breaks by Kodali, Sravan, Meyer-Nava, Silvia, Landry, Stephen, Chakraborty, Arijita, Rivera-Mulia, Juan Carlos, Feng, Wenyi

“…Common fragile sites (CFSs) are specific regions of all individuals' genome that are predisposed to DNA double strand breaks (DSBs) and undergo subsequent…”
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Editorial: The Role of RNA in Genome Stability: To Wreck or Repair? by Gómez-González, Belén, Dutta, Arijit, Feng, Wenyi

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Genome-wide mapping of DNA double-strand breaks from eukaryotic cell cultures using Break-seq by Joshi, Ishita, DeRycke, Jenna, Palmowski, Megan, LeSuer, Robert, Feng, Wenyi

“…We describe a genome-wide DNA double-strand break (DSB) mapping technique, Break-seq. In this protocol, we provide step-by-step instructions for cell embedment…”
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Replication stress induces global chromosome breakage in the fragile X genome by Chakraborty, Arijita, Jenjaroenpun, Piroon, Li, Jing, El Hilali, Sami, McCulley, Andrew, Haarer, Brian, Hoffman, Elizabeth A., Belak, Aimee, Thorland, Audrey, Hehnly, Heidi, Schildkraut, Carl L., Chen, Chun-long, Kuznetsov, Vladimir A., Feng, Wenyi

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Genomic mapping of single-stranded DNA in hydroxyurea-challenged yeasts identifies origins of replication by Brewer, Bonita J, Feng, Wenyi, Collingwood, David, Boeck, Max E, Fox, Lindsay A, Alvino, Gina M, Fangman, Walton L, Raghuraman, Mosur K

“…During DNA replication one or both strands transiently become single stranded: first at the sites where initiation of DNA synthesis occurs (known as origins of…”
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A Tale of Loops and Tails: The Role of Intrinsically Disordered Protein Regions in R-Loop Recognition and Phase Separation by Dettori, Leonardo G, Torrejon, Diego, Chakraborty, Arijita, Dutta, Arijit, Mohamed, Mohamed, Papp, Csaba, Kuznetsov, Vladimir A, Sung, Patrick, Feng, Wenyi, Bah, Alaji

“…R-loops are non-canonical, three-stranded nucleic acid structures composed of a DNA:RNA hybrid, a displaced single-stranded (ss)DNA, and a trailing ssRNA…”
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Testing a Nanocrossbar for Multiple Fault Detection by Wenyi Feng, Lombardi, Fabrizio, Almurib, Haider A. F., Kumar, T. Nandha

“…This paper proposes an approach for testing a nanocrossbar switch; fault detection is considered in the presence of faulty switches and nets (of a permanent…”
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Schizosaccharomyces pombe Cells Lacking the Amino-Terminal Catalytic Domains of DNA Polymerase Epsilon Are Viable but Require the DNA Damage Checkpoint Control by Feng, Wenyi, D'Urso, Gennaro

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multi-view multi-manifold learning with local and global structure preservation by Feng, Wenyi, Wang, Zhe

“…Most existing multi-view learning methods adopt a single geometrical model to describe multi-class and heterogeneous data on the original feature space without…”
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K-way partitioning based packing for FPGA logic blocks without input bandwidth constraint by Wenyi Feng

“…Cluster-based logic blocks from most commercial FPGA products do not have an input bandwidth constraint, i.e., limiting the number of signals going from…”
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The Essence of Replication Timing: Determinants and Significance by Lucas, Isabelle, Feng, Wenyi

“…In eukaryotic organisms, chromosomal DNA replication initiates at multiple sites on the chromosome at different times, following a temporal replication…”
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Incision of damaged DNA in the presence of an impaired Smc5/6 complex imperils genome stability by Peng, Jie, Feng, Wenyi

“…The Smc5/6 complex is implicated in homologous recombination-mediated DNA repair during DNA damage or replication stress. Here, we analysed genome-wide…”
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Adaptive weighted dictionary representation using anchor graph for subspace clustering by Feng, Wenyi, Wang, Zhe, Xiao, Ting, Yang, Mengping

“…Samples are commonly represented as sparse vectors in many dictionary representation algorithms. However, this method may result in loss of discriminatory…”
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Mec1/ATR, the Program Manager of Nucleic Acids Inc by Feng, Wenyi

“…Eukaryotic cells are equipped with surveillance mechanisms called checkpoints to ensure proper execution of cell cycle events. Among these are the checkpoints…”
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