Search Results - "Feng, Wanjing"
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Identifying an immunosenescence-associated gene signature in gastric cancer by integrating bulk and single-cell sequencing data
Published in Scientific reports (24-07-2024)“…It has been believed that immunosenescence plays a crucial role in tumorigenesis and cancer therapy. Nevertheless, there is still a lack of understanding…”
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Multi-dimension metabolic prognostic model for gastric cancer
Published in Frontiers in endocrinology (Lausanne) (2023)“…Metabolic reprogramming is involved in different stages of tumorigenesis. There are six widely recognized tumor-associated metabolic pathways, including…”
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A pan-cancer analysis of HER2 index revealed transcriptional pattern for precise selection of HER2-targeted therapy
Published in EBioMedicine (01-12-2020)“…The prevalence of HER2 alterations in pan-cancer indicates a broader range of application of HER2-targeted therapies; however, biomarkers for such therapies…”
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Identification of a Four-Gene-Based SERM Signature for Prognostic and Drug Sensitivity Prediction in Gastric Cancer
Published in Frontiers in oncology (12-01-2022)“…Gastric cancer (GC) is a highly molecular heterogeneous tumor with poor prognosis. Epithelial-mesenchymal transition (EMT) process and cancer stem cells (CSCs)…”
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A Point-of-Interest Recommendation Algorithm Combining Social Influence and Geographic Location Based on Belief Propagation
Published in IEEE access (2020)“…The location-based social network (LBSN) contains a large amount of user check-in data informations, in order to better improve the recommendation performance…”
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GepLiver: an integrative liver expression atlas spanning developmental stages and liver disease phases
Published in Scientific data (10-06-2023)“…Chronic liver diseases usually developed through stepwise pathological transitions under the persistent risk factors. The molecular changes during liver…”
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Clinicopathological Analysis and Treatment of Adult Patients with Inflammatory Myofibroblastic Tumor: A 15-Year Single- Center Study
Published in Cancer research and treatment (01-07-2023)“…Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal malignancy that occurs primarily in children and adolescents. The clinical and pathological…”
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Genomic pattern of intratumor heterogeneity predicts the risk of progression in early stage diffuse large B-cell lymphoma
Published in Carcinogenesis (New York) (25-11-2019)“…Abstract Intratumor heterogeneity (ITH) plays an important role in tumor development, metastases, recurrence and has impact on clinical diagnosis, therapeutic…”
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Genotype–immunophenotype analysis reveals the immunogenomic subtype and prognosis of multiple myeloma
Published in Carcinogenesis (New York) (31-12-2020)“…Abstract Immune dysfunction plays an important role in tumour development, recurrence, therapeutic responses and overall survival (OS). Multiple myeloma (MM)…”
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Efficacy prediction of targeted therapy for gastric cancer: The current status (Review)
Published in Molecular medicine reports (01-08-2018)“…Despite significant progress in the treatment of gastric cancer (GC), the prognosis remains poor and the mortality is high. Targeted drugs have been…”
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Envafolimab in combination with lenvatinib and albumin paclitaxel for previously treated advanced gastric/gastroesophageal junction adenocarcinoma: Preliminary analysis of a phase II, two-cohort study
Published in Journal of clinical oncology (01-06-2024)“…e16039 Background: The combination of first-line chemotherapy and PD-1 has emerged as a standard treatment, enhancing the efficacy in advanced…”
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Intra-tumoral heterogeneity and immune responses predicts prognosis of gastric cancer
Published in Aging (Albany, NY.) (26-11-2020)“…Chemotherapy resistance eventually develops in patients with gastric cancer (GC). Intra-tumoral heterogeneity (ITH) refers to the intercellular genetic…”
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Single cell and bulk RNA sequencing identifies tumor microenvironment subtypes and chemoresistance-related IGF1+ cancer-associated fibroblast in gastric cancer
Published in Biochimica et biophysica acta. Molecular basis of disease (01-04-2024)“…The tumor microenvironment (TME) significantly influences prognosis and drug resistance in various tumors, yet its heterogeneity and the mechanisms affecting…”
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Baseline serum lactate dehydrogenase level predicts survival benefit in patients with metastatic colorectal cancer receiving bevacizumab as first-line chemotherapy: a systematic review and meta-analysis of 7 studies and 1,219 patients
Published in Annals of translational medicine (01-04-2019)“…Bevacizumab, a humanized monoclonal antibody against vascular epithelial growth factor, plays a significant role in first-line, second-line,…”
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Phase III trial comparing XELOX regimen (oxaliplatin plus capecitabine) versus EOX regimen (epirubicin, oxaliplatin and capecitabine) as first-line treatment for advanced gastric cancer: EXELOX trial
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 4014 Background: At present, there is no standard chemotherapy regimen for advanced gastric cancer (AGC), and there is no consensus whether the…”
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A STING-related prognostic score predicts high-risk patients of colorectal cancer and provides insights into immunotherapy
Published in Annals of translational medicine (01-01-2021)“…Targeted therapeutic strategies for advanced colorectal cancer (CRC) have been limited. STING is crucial to the antitumor immunotherapy, for it stimulates IFN…”
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Severe loss of visceral fat and skeletal muscle after chemotherapy predicts poor prognosis in metastatic gastric cancer patients without gastrectomy
Published in Journal of Cancer (01-01-2020)“…: The influence of body composition parameters in cancer prognosis attracted researchers' attention. This study investigated the role of visceral fat and…”
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Influence of SLCO1B1 in gastric cancer patients treated with EOF chemotherapy
Published in Oncology letters (01-10-2018)“…Cytochrome-P450 enzymes, ATP-binding cassette transporters, and solute carriers mediate drug metabolism as metabolic enzymes and membrane transporters,…”
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