Search Results - "Feng, Meiqing"

Doxorubicin-loaded bacterial outer-membrane vesicles exert enhanced anti-tumor efficacy in non-small-cell lung cancer by Kuerban, Kudelaidi, Gao, Xiwen, Zhang, Hui, Liu, Jiayang, Dong, Mengxue, Wu, Lina, Ye, Ruihong, Feng, Meiqing, Ye, Li

“…More efficient drug delivery system and formulation with less adverse effects are needed for the clinical application of broad-spectrum antineoplastic agent…”
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Inhibition of PCSK9 enhances the antitumor effect of PD-1 inhibitor in colorectal cancer by promoting the infiltration of CD8+ T cells and the exclusion of Treg cells by Wang, Rui, Liu, Hongchuan, He, Peng, An, Duopeng, Guo, Xiaohan, Zhang, Xuyao, Feng, Meiqing

“…Immunotherapy especially immune checkpoint inhibitors (ICIs) has brought favorable clinical results for numerous cancer patients. However, the efficacy of ICIs…”
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A biomimetic nanovector-mediated targeted cholesterol-conjugated siRNA delivery for tumor gene therapy by Ding, Yang, Wang, Wei, Feng, Meiqing, Wang, Yu, Zhou, Jianping, Ding, Xuefang, Zhou, Xin, Liu, Congyan, Wang, Ruoning, Zhang, Qiang

“…Abstract RNA interference holds tremendous potential as a therapeutic approach of malignant tumors. However, safe and efficient nanovectors are extremely lack…”
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Epidemiological and genomic characteristics of Acinetobacter baumannii from different infection sites using comparative genomics by Bian, Xingchen, Liu, Xiaofen, Zhang, Xuefei, Li, Xin, Zhang, Jing, Zheng, Huajun, Song, Sichao, Li, Xiang, Feng, Meiqing

“…Abstract Background Acinetobacter baumannii is a common nosocomial pathogen that poses a huge threat to global health. Owing to the severity of A. baumannii…”
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Blocking autophagy improves the anti-tumor activity of afatinib in lung adenocarcinoma with activating EGFR mutations in vitro and in vivo by Hu, Xiangxiang, Shi, Si, Wang, Huan, Yu, Xiaochen, Wang, Qian, Jiang, Shanshan, Ju, Dianwen, Ye, Li, Feng, Meiqing

“…Afatinib, a second-generation tyrosine kinase inhibitor (TKI), has been approved for the treatment of advanced EGFR -mutant non-small cell lung cancer (NSCLC)…”
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Land Use Dynamic Changes in an Arid Inland River Basin Based on Multi-Scenario Simulation by Hou, Yifeng, Chen, Yaning, Li, Zhi, Li, Yupeng, Sun, Fan, Zhang, Shuai, Wang, Chuan, Feng, Meiqing

“…The Tarim River Basin is the largest inland river basin in China. It is located in an extremely arid region, where agriculture and animal husbandry are the…”
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Reversal of Multidrug Resistance by Apolipoprotein A1-Modified Doxorubicin Liposome for Breast Cancer Treatment by An, Duopeng, Yu, Xiaochen, Jiang, Lijing, Wang, Rui, He, Peng, Chen, Nanye, Guo, Xiaohan, Li, Xiang, Feng, Meiqing

“…Multidrug resistance (MDR) remains a major problem in cancer therapy and is characterized by the overexpression of p-glycoprotein (P-gp) efflux pump,…”
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Influence of Lipopolysaccharide-Interacting Peptides Fusion with Endolysin LysECD7 and Fatty Acid Derivatization on the Efficacy against Acinetobacter baumannii Infection In Vitro and In Vivo by Li, Xiaowan, Shangguan, Wenwen, Yang, Xiaoqian, Hu, Xiaoyue, Li, Yanan, Zhao, Wenjie, Feng, Meiqing, Feng, Jun

“…has developed multiple drug resistances, posing a significant threat to antibiotic efficacy. LysECD7, an endolysin derived from phages, could be a promising…”
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Correction to: epidemiological and genomic characteristics of A. baumannii from different infection sites using comparative genomics by Bian, Xingchen, Liu, Xiaofen, Zhang, Xuefei, Li, Xin, Zhang, Jing, Zheng, Huajun, Song, Sichao, Li, Xiang, Feng, Meiqing

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A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT by Fu, Zhihao, Liu, Hongchuan, Wang, Lan, Yu, Chuanfei, Yang, Yalan, Feng, Meiqing, Wang, Junzhi

“…T cell immunoglobulin and ITIM domain (TIGIT) is a novel immune checkpoint that has been considered as a target in cancer immunotherapy. Current available…”
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Novel nitroxoline derivative combating resistant bacterial infections through outer membrane disruption and competitive NDM-1 inhibition by He, Peng, Huang, Sijing, Wang, Rui, Yang, Yunkai, Yang, Shangye, Wang, Yue, Qi, Mengya, Li, Jiyang, Liu, Xiaofen, Zhang, Xuyao, Feng, Meiqing

“…New Delhi metallo- -lactamase-1 (NDM-1) has rapidly disseminated worldwide, leading to multidrug resistance and worse clinical prognosis. Designing and…”
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Pharmacokinetic/Pharmacodynamic Based Breakpoints of Polymyxin B for Bloodstream Infections Caused by Multidrug-Resistant Gram-Negative Pathogens by Bian, Xingchen, Liu, Xiaofen, Hu, Fupin, Feng, Meiqing, Chen, Yuancheng, Bergen, Phillip J, Li, Jian, Li, Xin, Guo, Yan, Zhang, Jing

“…The latest PK/PD findings have demonstrated negligible efficacy of intravenous polymyxins against pulmonary infections. We investigated…”
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Nemonoxacin Has Immunoprotective Effects on Reducing Mortality in Lipopolysaccharide-Induced Mouse Sepsis Model by Chen, Nanye, Li, Xin, Guo, Beining, Zou, Jun, Lin, Dongfang, Li, Xiang, Huang, Jinwei, Feng, Meiqing, Zhao, Xu

“…Nemonoxacin is a novel non-fluorinated quinolone. The effect of nemonoxacin on modulation of host immune response is not known. We sought to determine whether…”
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Transcriptomic investigations of polymyxins and colistin/sulbactam combination against carbapenem-resistant Acinetobacter baumannii by Bian, Xingchen, Li, Mengyao, Liu, Xiaofen, Zhu, Yan, Li, Jian, Bergen, Phillip J., Li, Wanzhen, Li, Xin, Feng, Meiqing, Zhang, Jing

“…Carbapenem-resistant Acinetobacter baumannii (CRAB) is a Priority 1 (Critical) pathogen urgently requiring new antibiotics. Polymyxins are a last-line option…”
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Peptide TQS169 prevents osteoporosis in rats by enhancing osteogenic differentiation and calcium absorption by Wang, Huan, Chen, Nanye, Shen, Shuru, Li, Huiyu, Hu, Xiangxiang, Yang, Yunkai, Yu, Xiaochen, Ye, Li, Zhou, Wei, Feng, Meiqing

“…[Display omitted] •A new kind of ossotide derived from bovine bone had the preventative effects on osteoporosis.•Calcium absorption was enhanced in rats with a…”
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Generated SecPen_NY-ESO-1_ubiquitin-pulsed dendritic cell cancer vaccine elicits stronger and specific T cell immune responses by Yang, Yunkai, Guo, Xiaohan, Hu, Bo, He, Peng, Jiang, Xiaowu, Wang, Zuohuan, Zhu, Huaxing, Hu, Lina, Yu, Minghua, Feng, Meiqing

“…Dendritic cell-based cancer vaccines (DC vaccines) have been proved efficient and safe in immunotherapy of various cancers, including melanoma, ovarian and…”
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Anti-hepatitis B Virus Activities of Geranium carolinianum L. Extracts and Identification of the Active Components by Li, Jiyang, Huang, Hai, Zhou, Wei, Feng, Meiqing, Zhou, Pei

“…The ethanol extract of Geranium carolinianum L., a domestic plant grown in China, was subjected to sequential extractions with different organic solvents. The…”
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Cationic poly(amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells by Li, Yubin, Wang, Shaofei, Wang, Ziyu, Qian, Xiaolu, Fan, Jiajun, Zeng, Xian, Sun, Yun, Song, Ping, Feng, Meiqing, Ju, Dianwen

“…Poly(amidoamine) (PAMAM) dendrimers are proposed as one of the most promising nanomaterials for biomedical applications because of their unique tree-like…”
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Pharmacokinetics and Pharmacodynamics of Nemonoxacin in a Neutropenic Murine Lung Infection Model Against Streptococcus Pneumoniae by Li, Xin, Chen, Yuancheng, Xu, Xiaoyong, Li, Yi, Fan, Yaxin, Liu, Xiaofen, Bian, Xingchen, Wu, Hailan, Zhao, Xu, Feng, Meiqing, Guo, Beining, Zhang, Jing

“…Nemonoxacin, a novel nonfluorinated quinolone for the treatment of community-acquired pneumonia. We reported the pharmacokinetic/pharmacodynamic (PK/PD)…”
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Autophagy plays a critical role in ChLym-1-induced cytotoxicity of non-hodgkin's lymphoma cells by Fan, Jiajun, Zeng, Xian, Li, Yubin, Wang, Shaofei, Wang, Ziyu, Sun, Yun, Gao, Hongjian, Zhang, Guoping, Feng, Meiqing, Ju, Dianwen

“…Autophagy is a critical mechanism in both cancer therapy resistance and tumor suppression. Monoclonal antibodies have been documented to kill tumor cells via…”
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