Search Results - "Feng, Liangzhu"
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Nano-graphene in biomedicine: theranostic applications
Published in Chemical Society reviews (01-01-2013)“…Owing to their unique physical and chemical properties, graphene and its derivatives such as graphene oxide (GO), reduced graphene oxide (RGO) and…”
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Functional Nanomaterials for Phototherapies of Cancer
Published in Chemical reviews (12-11-2014)“…Cheng et al explore various functional nanomaterials used in phototherapies of cancer. They focus on topics such as photothermal therapy using nanoagents and…”
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Tumor-killing nanoreactors fueled by tumor debris can enhance radiofrequency ablation therapy and boost antitumor immune responses
Published in Nature communications (14-07-2021)“…Radiofrequency ablation (RFA) is clinically adopted to destruct solid tumors, but is often incapable of completely ablating large tumors and those with…”
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Photothermally Enhanced Photodynamic Therapy Delivered by Nano-Graphene Oxide
Published in ACS nano (27-09-2011)“…Graphene with unique physical and chemical properties has shown various potential applications in biomedicine. In this work, a photosensitizer molecule,…”
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Ultrasmall Oxygen‐Deficient Bimetallic Oxide MnWOX Nanoparticles for Depletion of Endogenous GSH and Enhanced Sonodynamic Cancer Therapy
Published in Advanced materials (Weinheim) (01-06-2019)“…Sonodynamic therapy (SDT) triggered by ultrasound (US) has attracted increasing attention owing to its abilities to overcome critical limitations including low…”
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H₂O₂-responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay
Published in Proceedings of the National Academy of Sciences - PNAS (23-05-2017)“…Abnormal H₂O₂ levels are closely related to many diseases, including inflammation and cancers. Herein, we simultaneously load HRP and its substrate,…”
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Light-Responsive, Singlet-Oxygen-Triggered On-Demand Drug Release from Photosensitizer-Doped Mesoporous Silica Nanorods for Cancer Combination Therapy
Published in Advanced functional materials (12-07-2016)“…Smart drug delivery systems with on‐demand drug release capability are rather attractive to realize highly specific cancer treatment. Herein, a novel…”
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Drug-Induced Self-Assembly of Modified Albumins as Nano-theranostics for Tumor-Targeted Combination Therapy
Published in ACS nano (26-05-2015)“…Paclitaxel (PTX) can bind to human serum albumin (HSA) via hydrophobic interaction, forming Abraxane, which is a U.S. Food and Drug Administration (FDA)…”
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Preparation and functionalization of graphene nanocomposites for biomedical applications
Published in Nature protocols (01-12-2013)“…Functionalized nano-graphene– and graphene-based nanocomposites have gained tremendous attention in the area of biomedicine in recent years owing to their…”
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The acidic tumor microenvironment: a target for smart cancer nano-theranostics
Published in National science review (01-03-2018)“…Abstract The acidic tumor microenvironment (TME), which mainly results from the high glycolytic rate of tumor cells, has been characterized as a hallmark of…”
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Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses
Published in Nature biomedical engineering (01-08-2018)“…Radiation therapy for cancer can lead to off-target toxicity and can be ineffective against hypoxic solid tumours and distant metastases. Here, we show that…”
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Catalase-loaded cisplatin-prodrug-constructed liposomes to overcome tumor hypoxia for enhanced chemo-radiotherapy of cancer
Published in Biomaterials (01-09-2017)“…Abstract Aiming at improved therapeutic efficacies, the combination of chemotherapy and radiotherapy (chemo-radiotherapy) has been widely studied and applied…”
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Polyethylene Glycol and Polyethylenimine Dual-Functionalized Nano-Graphene Oxide for Photothermally Enhanced Gene Delivery
Published in Small (Weinheim an der Bergstrasse, Germany) (10-06-2013)“…Graphene oxide (GO) has been extensively explored in nanomedicine for its excellent physiochemical, electrical, and optical properties. Here, polyethylene…”
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A Hypoxia‐Responsive Albumin‐Based Nanosystem for Deep Tumor Penetration and Excellent Therapeutic Efficacy
Published in Advanced materials (Weinheim) (01-06-2019)“…Uncontrolled cancer cell proliferation, insufficient blood flow, and inadequate endogenous oxygen lead to hypoxia in tumor tissues. Herein, a unique type of…”
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Drug-induced co-assembly of albumin/catalase as smart nano-theranostics for deep intra-tumoral penetration, hypoxia relieve, and synergistic combination therapy
Published in Journal of controlled release (10-10-2017)“…The abnormal tumor microenvironment (TME) featured with hypoxia, acidosis, dense extracellular matrix and increased tumor interstitial fluid pressure is…”
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Liposomes co-loaded with metformin and chlorin e6 modulate tumor hypoxia during enhanced photodynamic therapy
Published in Nano research (01-04-2017)“…Though photodynamic therapy (PDT) has been widely used in the non-invasive destruction of solid tumors, the therapeutic efficacy of PDT is often limited by the…”
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The advancing uses of nano-graphene in drug delivery
Published in Expert opinion on drug delivery (01-04-2015)“…Graphene has been received with great interest in various fields including biomedical applications. Due to its ultrahigh surface area and easy surface…”
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Near-Infrared Absorbing Polymeric Nanoparticles as a Versatile Drug Carrier for Cancer Combination Therapy
Published in Advanced functional materials (23-12-2013)“…Poly(3,4‐ethylenedioxythiophene):poly(4‐styrenesulfonate) (PEDOT:PSS) nanoparticles, after being coated with polyethylene glycol (PEG), are used as a drug…”
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Surface Coating-Dependent Cytotoxicity and Degradation of Graphene Derivatives: Towards the Design of Non-Toxic, Degradable Nano-Graphene
Published in Small (Weinheim an der Bergstrasse, Germany) (01-04-2014)“…With the increasing interests of using graphene and its derivatives in the area of biomedicine, the systematic evaluation of their potential risks and impacts…”
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A functionalized graphene oxide-iron oxide nanocomposite for magnetically targeted drug delivery, photothermal therapy, and magnetic resonance imaging
Published in Nano research (01-03-2012)“…Two-dimensional graphene and its composite nanomaterials offer interesting physical/chemical properties and have been extensively explored in a wide range of…”
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