Search Results - "Feng, Jiannan"
-
1
Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission
Published in Science China. Life sciences (01-03-2020)Get full text
Journal Article -
2
Energy Platform for Directed Charge Transfer in the Cascade Z‐Scheme Heterojunction: CO2 Photoreduction without a Cocatalyst
Published in Angewandte Chemie International Edition (13-09-2021)“…A universal strategy is developed to construct a cascade Z‐Scheme system, in which an effective energy platform is the core to direct charge transfer and…”
Get full text
Journal Article -
3
Dimension‐Matched Zinc Phthalocyanine/BiVO4 Ultrathin Nanocomposites for CO2 Reduction as Efficient Wide‐Visible‐Light‐Driven Photocatalysts via a Cascade Charge Transfer
Published in Angewandte Chemie International Edition (05-08-2019)“…Cascade charge transfer was realized by a H‐bond linked zinc phthalocyanine/BiVO4 nanosheet (ZnPc/BVNS) composite, which subsequently works as an efficient…”
Get full text
Journal Article -
4
Structure-guided affinity maturation of a novel human antibody targeting the SARS-CoV-2 nucleocapsid protein
Published in Scientific reports (19-05-2022)“…The continuous mutation of SARS-CoV-2 has presented enormous challenges to global pandemic prevention and control. Recent studies have shown evidence that the…”
Get full text
Journal Article -
5
Spliceosome protein Eftud2 promotes colitis-associated tumorigenesis by modulating inflammatory response of macrophage
Published in Mucosal immunology (01-09-2019)“…Alternative splicing (AS) of mRNA is known to be involved in regulation of immune cell differentiation and activation. Elongation factor Tu GTP binding domain…”
Get full text
Journal Article -
6
Transcriptional repression of IKKβ by p53 in arsenite-induced GADD45α accumulation and apoptosis
Published in Oncogene (31-01-2019)“…Our previous studies revealed that GADD45α is a liable protein, which undergoes MDM2-dependent constitutive ubiquitination and degradation in resting HepG2…”
Get full text
Journal Article -
7
A novel human anti‐AXL monoclonal antibody attenuates tumour cell migration
Published in Scandinavian journal of immunology (01-08-2019)“…TAM family members (TYRO3, AXL and MERTK) play essential roles in the resolution of inflammation and in infectious diseases and cancer. AXL, a tyrosine kinase…”
Get full text
Journal Article -
8
Development and characterization of an antibody that recognizes influenza virus N1 neuraminidases
Published in PloS one (09-05-2024)“…Influenza A viruses (IAVs) continue to pose a huge threat to public health, and their prevention and treatment remain major international issues. Neuraminidase…”
Get full text
Journal Article -
9
A novel MARV glycoprotein-specific antibody with potentials of broad-spectrum neutralization to filovirus
Published in eLife (25-03-2024)“…Marburg virus (MARV) is one of the filovirus species that cause deadly hemorrhagic fever in humans, with mortality rates up to 90%. Neutralizing antibodies…”
Get full text
Journal Article -
10
High-affinity decoy protein, nFD164, with an inactive Fc region as a potential therapeutic drug targeting CD47
Published in Biomedicine & pharmacotherapy (01-06-2023)“…CD47, as an innate immune checkpoint molecule, is an important target of cancer immunotherapy. We previously reported that a high-affinity SIRPα variant FD164…”
Get full text
Journal Article -
11
COMSUC: A web server for the identification of consensus molecular subtypes of cancer based on multiple methods and multi-omics data
Published in PLoS computational biology (18-03-2021)“…Extensive amounts of multi-omics data and multiple cancer subtyping methods have been developed rapidly, and generate discrepant clustering results, which…”
Get full text
Journal Article -
12
Unveiling novel insights into human IL-6 − IL-6R interaction sites through 3D computer-guided docking and systematic site mutagenesis
Published in Scientific reports (07-08-2024)“…The cytokine interleukin-6 (IL-6) plays a crucial role in autoimmune and inflammatory diseases. Understanding the precise mechanism of IL-6 interaction at the…”
Get full text
Journal Article -
13
Two-mAb cocktail protects macaques against the Makona variant of Ebola virus
Published in Science translational medicine (09-03-2016)“…The 2014-2015 Ebola virus (EBOV) outbreak in West Africa highlighted the urgent need for specific therapeutic interventions for infected patients. The…”
Get more information
Journal Article -
14
SP1 promotes tumor angiogenesis and invasion by activating VEGF expression in an acquired trastuzumab-resistant ovarian cancer model
Published in Oncology reports (01-11-2017)“…Ovarian cancer is one of the most common gynecologic cancers and the leading cause of mortality in women worldwide. HER2/neu is overexpressed in various types…”
Get full text
Journal Article -
15
Negative regulation of Nod‐like receptor protein 3 inflammasome activation by T cell Ig mucin‐3 protects against peritonitis
Published in Immunology (01-01-2018)“…Summary The Nod‐like receptor protein 3 (NLRP3) inflammasome plays roles in host defence against invading pathogens and in the development of autoimmune…”
Get full text
Journal Article -
16
Securing top-k query processing in two-tiered sensor networks
Published in Connection science (02-01-2021)“…Integrity and privacy are two important secure matrices in cyber security. Due to the limited resources and computing capability of the sensor nodes, it is…”
Get full text
Journal Article -
17
Improved HHT-microstate analysis of EEG in nicotine addicts
Published in Frontiers in neuroscience (24-05-2023)“…Substance addiction is a chronic disease which causes great harm to modern society and individuals. At present, many studies have applied EEG analysis methods…”
Get full text
Journal Article -
18
Inhibitory effect of four types of tea on the in vitro digestion of starch
Published in Food frontiers (01-12-2020)“…Phenolic compounds have been shown to decrease the rate of starch hydrolysis by inhibiting digestive enzymes for starch. Tea, rich in phenolic compounds, has…”
Get full text
Journal Article -
19
Development of novel monoclonal antibodies for blocking NF-κB activation induced by CD2v protein in African swine fever virus
Published in Frontiers in immunology (23-05-2024)“…CD2v, a critical outer envelope glycoprotein of the African swine fever virus (ASFV), plays a central role in the hemadsorption phenomenon during ASFV…”
Get full text
Journal Article -
20
Tim-3 promotes tumor-promoting M2 macrophage polarization by binding to STAT1 and suppressing the STAT1-miR-155 signaling axis
Published in Oncoimmunology (01-09-2016)“…T cell Ig mucin-3 (Tim-3), an immune checkpoint inhibitor, shows therapeutic potential. However, the molecular mechanism by which Tim-3 regulates immune…”
Get full text
Journal Article