Search Results - "Feng, Jianfang"
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Procyanidin A1 Alleviates Inflammatory Response induced by LPS through NF-κB, MAPK, and Nrf2/HO-1 Pathways in RAW264.7 cells
Published in Scientific reports (21-10-2019)“…Inflammation is a complex physiological process that poses a serious threat to people’s health. However, the potential molecular mechanisms of inflammation are…”
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2
Myricetin inhibits proliferation and induces apoptosis and cell cycle arrest in gastric cancer cells
Published in Molecular and cellular biochemistry (01-10-2015)“…Myricetin is a flavonoid that is abundant in fruits and vegetables and has protective effects against cancer and diabetes. However, the mechanism of action of…”
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3
Nose-to-brain delivery of borneol modified tanshinone IIA nanoparticles in prevention of cerebral ischemia/reperfusion injury
Published in Drug delivery (01-01-2021)“…Targeted treatment of cerebral ischemia/reperfusion injury (CIRI) remains a problem due to the difficulty in drug delivery across the blood-brain barrier…”
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4
Procyanidin A2, a polyphenolic compound, exerts anti-inflammatory and anti-oxidative activity in lipopolysaccharide-stimulated RAW264.7 cells
Published in PloS one (05-08-2020)“…Procyandin A2 (PCA2) is a polyphenolic compound which is isolated from grape seeds. It has been reported that PCA2 exhibits antioxidative and anti-inflammatory…”
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5
Formation of perfluorocarboxylic acids from photodegradation of tetrahydroperfluorocarboxylic acids in water
Published in The Science of the total environment (10-03-2019)“…Tetrahydroperfluorocarboxylic acids (2H,2H,3H,3H-PFCAs) have aroused the interest of scholars worldwide due to their potential to generate perfluorinated…”
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6
Andrographolide/Phospholipid/Cyclodextrin Complex-Loaded Nanoemulsion: Preparation, Optimization, in Vitro and in Vivo Evaluation
Published in Biological & pharmaceutical bulletin (01-08-2022)“…Andrographolide (AG), a natural product with various pharmacological effects, exhibited low oral bioavailability owing to its poor solubility, stability, and…”
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7
Therapeutic effects of Bombax ceiba flower aqueous extracts against loperamide-induced constipation in mice
Published in Pharmaceutical biology (01-12-2023)“…Bombax ceiba Linnaeus (Bombacaceae) is known as silk cotton tree, the flowers of which are used in many medicinal applications. To investigate the therapeutic…”
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8
Remodeling the blood–brain barrier microenvironment by natural products for brain tumor therapy
Published in Acta pharmaceutica Sinica. B (01-09-2017)“…Brain tumor incidence shows an upward trend in recent years; brain tumors account for 5% of adult tumors, while in children, this figure has increased to 70%…”
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9
Nanocrystal-Loaded Micelles for the Enhanced In Vivo Circulation of Docetaxel
Published in Molecules (Basel, Switzerland) (24-07-2021)“…Prolonging in vivo circulation has proved to be an efficient route for enhancing the therapeutic effect of rapidly metabolized drugs. In this study, we aimed…”
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10
Occurrence of Perfluoroalkyl Acids Including Perfluorooctane Sulfonate Isomers in Huai River Basin and Taihu Lake in Jiangsu Province, China
Published in Environmental science & technology (15-01-2013)“…The spatial distribution of 10 perfluoroalkyl acids including linear and branched (six monotrifluoromethyl isomers) perfluorooctane sulfonate (PFOS) in surface…”
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11
l-Carnitine conjugated chitosan-stearic acid polymeric micelles for improving the oral bioavailability of paclitaxel
Published in Drug delivery (01-01-2020)“…A delivery system based on l-carnitine (LC) conjugated chitosan (CS)-stearic acid polymeric micelles has been developed for improving the oral bioavailability…”
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12
Preparation, In Vitro and In Vivo Evaluation of Nanoemulsion In Situ Gel for Transnasal Delivery of Traditional Chinese Medicine Volatile Oil from Ligusticum sinense Oliv.cv. Chaxiong
Published in Molecules (Basel, Switzerland) (07-11-2022)“…Ischemic stroke is a difficult-to-treat brain disease that may be attributed to a limited therapeutic time window and lack of effective clinical drugs…”
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13
Preparation and in vitro and in vivo evaluations of 10-hydroxycamptothecin liposomes modified with stearyl glycyrrhetinate
Published in Drug delivery (01-01-2019)“…10-Hydroxycamptothecin (HCPT) liposomes surface modified with stearyl glycyrrhetinate (SG) were prepared by the film dispersion method. Characterization of the…”
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14
Anti-liver fibrosis effects of the total flavonoids of litchi semen on CCl4-induced liver fibrosis in rats associated with the upregulation of retinol metabolism
Published in Pharmaceutical biology (01-12-2022)“…The litchi semen are traditional medications for treating liver fibrosis (LF) in China. The mechanism remains unclear. This study investigates the anti-liver…”
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15
Research Progress on the Mechanism of Nanoparticles Crossing the Intestinal Epithelial Cell Membrane
Published in Pharmaceutics (25-06-2023)“…Improving the stability of drugs in the gastrointestinal tract and their penetration ability in the mucosal layer by implementing a nanoparticle delivery…”
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16
Combined integrin αvβ3 and lactoferrin receptor targeted docetaxel liposomes enhance the brain targeting effect and anti-glioma effect
Published in Journal of nanobiotechnology (23-12-2021)“…Abstract The integrin α v β 3 receptor and Lactoferrin receptor (LfR) are over-expressed in both cerebral microvascular endothelial cells and glioma cells. RGD…”
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17
Resveratrol-Loaded Dissolving Microneedles: Fabrication and in vitro Evaluation
Published in Pharmaceutical fronts (08-11-2024)“…Abstract Resveratrol (Res), an active ingredient derived from a multitude of plants, exhibits multiple pharmacological activities. However, its poor water…”
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18
Multi-functional chitosan copolymer modified nanocrystals as oral andrographolide delivery systems for enhanced bioavailability and anti-inflammatory efficacy
Published in Drug delivery (31-12-2022)“…Modifying nanocrystals with functional materials have been common strategy to enlarge the enhancing ability on oral absorption via nanocrystals; however,…”
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19
Identification of key genes associated with the progression of liver fibrosis to hepatocellular carcinoma based on iTRAQ proteomics and GEO database
Published in Annals of hepatology (01-05-2022)“…Liver fibrosis (LF) often leads to cirrhosis and even hepatocellular carcinoma (HCC), but the molecular mechanism remains unclear. The aims of the present…”
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“Guide” of muscone modification enhanced brain‐targeting efficacy and anti‐glioma effect of lactoferrin modified DTX liposomes
Published in Bioengineering & translational medicine (01-03-2023)“…Glioma is one of the most aggressive malignant diseases for human health. It is difficult to resect completely due to their invasiveness. The targeted…”
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