Search Results - "Feng, Guoyin"

Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia by Li, Zhiqiang, Chen, Jianhua, Yu, Hao, He, Lin, Xu, Yifeng, Zhang, Dai, Yi, Qizhong, Li, Changgui, Li, Xingwang, Shen, Jiawei, Song, Zhijian, Ji, Weidong, Wang, Meng, Zhou, Juan, Chen, Boyu, Liu, Yahui, Wang, Jiqiang, Wang, Peng, Yang, Ping, Wang, Qingzhong, Feng, Guoyin, Liu, Benxiu, Sun, Wensheng, Li, Baojie, He, Guang, Li, Weidong, Wan, Chunling, Xu, Qi, Li, Wenjin, Wen, Zujia, Liu, Ke, Huang, Fang, Ji, Jue, Ripke, Stephan, Yue, Weihua, Sullivan, Patrick F, O'Donovan, Michael C, Shi, Yongyong

“…A genome-wide association analysis using data from Chinese individuals combined with a transethnic meta-analysis of Psychiatry Genomics Consortium data…”
Get full text

Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β‐Catenin Signaling by Lin, Chuwen, Jiang, Xuan, Dai, Zhongquan, Guo, Xizhi, Weng, Tujun, Wang, Jun, Li, Yinghui, Feng, Guoyin, Gao, Xiang, He, Lin

“…Reduced mechanical stress leads to bone loss, as evidenced by disuse osteoporosis in bedridden patients and astronauts. Osteocytes have been identified as…”
Get full text

CACNA1C, schizophrenia and major depressive disorder in the Han Chinese population by He, Kuanjun, An, Zhiguo, Wang, Qingzhong, Li, Tao, Li, Zhiqiang, Chen, Jianhua, Li, Wenjin, Wang, Ti, Ji, Jue, Feng, Guoyin, Lin, He, Yi, Qizhong, Shi, Yongyong

“…Common psychiatric disorders are highly heritable, indicating that genetic factors play an important role in their aetiology. The CACNA1C gene, which codes for…”
Get full text

Genome-wide Analysis of the Role of Copy Number Variation in Schizophrenia Risk in Chinese by Li, Zhiqiang, Chen, Jianhua, Xu, Yifeng, Yi, Qizhong, Ji, Weidong, Wang, Peng, Shen, Jiawei, Song, Zhijian, Wang, Meng, Yang, Ping, Wang, Qingzhong, Feng, Guoyin, Liu, Benxiu, Sun, Wensheng, Xu, Qi, Li, Baojie, He, Lin, He, Guang, Li, Wenjin, Wen, Zujia, Liu, Ke, Huang, Fang, Zhou, Juan, Ji, Jue, Li, Xingwang, Shi, Yongyong

“…Abstract Background Compelling evidence suggested the role of copy number variations (CNVs) in schizophrenia susceptibility. Most of the evidence was from…”
Get full text

Metabolomic Profiling to Identify Potential Serum Biomarkers for Schizophrenia and Risperidone Action by Xuan, Jiekun, Pan, Guihua, Qiu, Yunping, Yang, Lun, Su, Mingming, Liu, Yumin, Chen, Jian, Feng, Guoyin, Fang, Yiru, Jia, Wei, Xing, Qinghe, He, Lin

“…Despite recent advances in understanding the pathophysiology of schizophrenia and the mechanisms of antipsychotic drug action, the development of biomarkers…”
Get full text

Common variants on 8p12 and 1q24.2 confer risk of schizophrenia by Shi, Yongyong, Li, Zhiqiang, Xu, Qi, Wang, Ti, Li, Tao, Shen, Jiawei, Zhang, Fengyu, Chen, Jianhua, Zhou, Guoquan, Ji, Weidong, Li, Baojie, Xu, Yifeng, Liu, Dengtang, Wang, Peng, Yang, Ping, Liu, Benxiu, Sun, Wensheng, Wan, Chunling, Qin, Shengying, He, Guang, Steinberg, Stacy, Cichon, Sven, Werge, Thomas, Sigurdsson, Engilbert, Tosato, Sarah, Palotie, Aarno, Nöthen, Markus M, Rietschel, Marcella, Ophoff, Roel A, Collier, David A, Rujescu, Dan, Clair, David St, Stefansson, Hreinn, Stefansson, Kari, Ji, Jue, Wang, Qingzhong, Li, Wenjin, Zheng, Linqing, Zhang, Hairong, Feng, Guoyin, He, Lin

“…Yongyong Shi, Lin He and colleagues report a genome-wide association study for schizophrenia in the Han Chinese population. They identify two new…”
Get full text

Rates of Adult Schizophrenia Following Prenatal Exposure to the Chinese Famine of 1959-1961 by St Clair, David, Xu, Mingqing, Wang, Peng, Yu, Yaqin, Fang, Yourong, Zhang, Feng, Zheng, Xiaoying, Gu, Niufan, Feng, Guoyin, Sham, Pak, He, Lin

“…CONTEXT Schizophrenia is a common major mental disorder. Intrauterine nutritional deficiency may increase the risk of schizophrenia. The main evidence comes…”
Get full text

Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case study by Yang, Lun, Wang, Kejian, Chen, Jian, Jegga, Anil G, Luo, Heng, Shi, Leming, Wan, Chunling, Guo, Xizhi, Qin, Shengying, He, Guang, Feng, Guoyin, He, Lin

“…In the era of personalized medical practice, understanding the genetic basis of patient-specific adverse drug reaction (ADR) is a major challenge. Clozapine…”
Get full text

Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice by Huang, Sixia, Zhu, Xuming, Liu, Yanfang, Tao, Yixin, Feng, Guoyin, He, Lin, Guo, Xizhi, Ma, Gang

“…Wnt proteins are secreted molecules that play multiple roles during hair follicle development and postnatal hair cycling. Wntless (Wls) is a cargo protein…”
Get full text

A genome-wide association study reveals association between common variants in an intergenic region of 4q25 and high-grade myopia in the Chinese Han population by Li, Zhiqiang, Qu, Jia, Xu, Xun, Zhou, Xiangtian, Zou, Haidong, Wang, Ning, Li, Tao, Hu, Xiaohan, Zhao, Qian, Chen, Peng, Li, Wenjin, Huang, Ke, Yang, Jun, He, Zangdong, Ji, Jue, Wang, Ti, Li, Junyan, Li, You, Liu, Jie, Zeng, Zhen, Feng, Guoyin, He, Lin, Shi, Yongyong

“…High-grade myopia (HM) is highly heritable, and has a high prevalence in the Han Chinese population. We carried out a genome-wide association study involving…”
Get full text

Rare CNVs and Tag SNPs at 15q11.2 Are Associated With Schizophrenia in the Han Chinese Population by QIAN ZHAO, TAO LI, GUOYIN FENG, ST CLAIR, David, LIN HE, YONGYONG SHI, XINZHI ZHAO, KE HUANG, TI WANG, ZHIQIANG LI, JUE JI, ZHEN ZENG, ZHAO ZHANG, KAN LI

“…Rare copy number variations (CNVs) were involved in the etiology of neuropsychiatric disorders, and some of them appeared to be shared risk factors for several…”
Get full text

Common Variants in Major Histocompatibility Complex Region and TCF4 Gene Are Significantly Associated with Schizophrenia in Han Chinese by Li, Tao, Li, Zhiqiang, Chen, Peng, Zhao, Qian, Wang, Ti, Huang, Ke, Li, JunYan, Li, You, Liu, Jie, Zeng, Zhen, Feng, GuoYin, He, Lin, Shi, YongYong

“…Background Schizophrenia is a complex major psychiatric disorder affecting ∼1% of the world population. Recently, in a genome-wide association study and a…”
Get full text

CNTNAP2 is significantly associated with schizophrenia and major depression in the Han Chinese population by Ji, Weidong, Li, Tao, Pan, Yaosheng, Tao, Hua, Ju, Kang, Wen, Zujia, Fu, Yingchun, An, Zhiguo, Zhao, Qian, Wang, Ti, He, Lin, Feng, Guoyin, Yi, Qizhong, Shi, Yongyong

“…Abstract CNTNAP2 , located on 7q35–36.1, encodes a single-pass transmembrane protein mediating cell–cell interactions in the nervous system. CNTNAP2 has been…”
Get full text

Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levels by Ma, Gang, Yu, Jiang, Xiao, Yue, Chan, Danny, Gao, Bo, Hu, Jianxin, He, Yongxing, Guo, Shengzhen, Zhou, Jian, Zhang, Lingling, Gao, Linghan, Zhang, Wenjuan, Kang, Yan, Cheah, Kathryn SE, Feng, Guoyin, Guo, Xizhi, Wang, Yujiong, Zhou, Cong-zhao, He, Lin

“…Brachydactyly type A1 （BDAI）, the first recorded Mendelian autosomal dominant disorder in humans, is characterized by a shortening or absence of the middle…”
Get full text

Altered Levels of Acute Phase Proteins in the Plasma of Patients with Schizophrenia by Yang, Yifeng, Wan, Chunling, Li, Huafang, Zhu, Hui, La, Yujuan, Xi, Zhengrui, Chen, Yongshuo, Jiang, Lei, Feng, Guoyin, He, Lin

“…Schizophrenia is a relatively common psychiatric syndrome that affects virtually all brain functions. We investigated the plasma proteome of 22 schizophrenia…”
Get full text

The PstI/RsaI and DraI polymorphisms of CYP2E1 and head and neck cancer risk: a meta-analysis based on 21 case-control studies by Tang, Kefu, Li, Yang, Zhang, Zhao, Gu, Yunmin, Xiong, Yuyu, Feng, Guoyin, He, Lin, Qin, Shengying

“…CYP2E1 encodes a member of the cytochrome P450 superfamily of enzymes which play a central role in activating and detoxifying many carcinogens and endogenous…”
Get full text

Common SNPs in myelin transcription factor 1-like (MYT1L): association with major depressive disorder in the Chinese Han population by Wang, Ti, Zeng, Zhen, Li, Tao, Liu, Jie, Li, Junyan, Li, You, Zhao, Qian, Wei, Zhiyun, Wang, Yang, Li, Baojie, Feng, Guoyin, He, Lin, Shi, Yongyong

“…Myelin transcription factor 1-like (MYT1L) is a member of the myelin transcription factor 1 (MYT1) gene family, and the neural specific,…”
Get full text

ITIH family genes confer risk to schizophrenia and major depressive disorder in the Han Chinese population by He, Kuanjun, Wang, Qingzhong, Chen, Jianhua, Li, Tao, Li, Zhiqiang, Li, Wenjin, Wen, Zujia, Qiang, Yu, Wang, Meng, Shen, Jiawei, Song, Zhijian, Ji, Jue, Feng, Guoyin, Qi, Shuguang, Lin, He, Shi, Yongyong, Cheng, Zaohuo

“…As a major extracellular matrix component, ITIHs played an important role in inflammation and carcinogenesis. Several genome-wide association studies have…”
Get full text

A systematic genetic polymorphism analysis of the CYP2C9 gene in four different geographical Han populations in mainland China by Xiong, Yuyu, Wang, Ming, Fang, Ke, Xing, Qinghe, Feng, Guoyin, Shen, Lu, He, Lin, Qin, Shengying

“…While many studies have been focused on CYP2C9*2 and *3 there was a lack of large full gene sequencing on CYP2C9, and this study was designed to fill this gap…”
Get full text

Systematic functional characterization of cytochrome P450 2E1 promoter variants in the Chinese Han population by Huang, Xunyi, Chen, Lili, Song, Wenlong, Chen, Ling, Niu, Jiamin, Han, Xia, Feng, Guoyin, He, Lin, Qin, Shengying

“…CYP2E1 promoter polymorphisms can lead to significant interindividual differences in expression of CYP2E1. Using a database of CYP2E1 gene polymorphisms…”
Get full text