Search Results - "Feng, Bing"

2‑(Pyridin-2-yl)isopropyl (PIP) Amine: An Enabling Directing Group for Divergent and Asymmetric Functionalization of Unactivated Methylene C(sp3)–H Bonds by Zhang, Qi, Shi, Bing-Feng

“…Conspectus Directing group (DG) assistance provides a good solution to the problems of reactivity and selectivity, two of the fundamental challenges in…”
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Transition Metal‐Catalyzed Enantioselective C−H Functionalization via Chiral Transient Directing Group Strategies by Liao, Gang, Zhang, Tao, Lin, Zhi‐Keng, Shi, Bing‐Feng

“…Transition metal‐catalyzed enantioselective functionalization of C−H bond, the most abundant functionality in organic molecules, has emerged as an expedient…”
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From Reactivity and Regioselectivity to Stereoselectivity: An Odyssey of Designing PIP Amine and Related Directing Groups for C—H Activation by Zhang, Qi, Shi, Bing‐Feng

“…Improving the reactivity and selectivity is a long pursuing goal in C—H functionalization reactions. In line with this goal, a well‐designed bidentate…”
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PERCH: A Unified Framework for Disease Gene Prioritization by Feng, Bing‐Jian

“…ABSTRACT To interpret genetic variants discovered from next‐generation sequencing, integration of heterogeneous information is vital for success. This article…”
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Atroposelective Synthesis of Axially Chiral Biaryls by Palladium‐Catalyzed Asymmetric C−H Olefination Enabled by a Transient Chiral Auxiliary by Yao, Qi‐Jun, Zhang, Shuo, Zhan, Bei‐Bei, Shi, Bing‐Feng

“…Atroposelective synthesis of axially chiral biaryls by palladium‐catalyzed C−H olefination, using tert‐leucine as an inexpensive, catalytic, and transient…”
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Site-selective functionalization of remote aliphatic C-H bonds via C-H metallation by Zhang, Qi, Shi, Bing-Feng

“…Directing group assistance provided a paradigm for controlling site-selectivity in transition metal-catalyzed C-H functionalization reactions. However, the…”
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Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp3)–H Bonds by Liu, Bin, Romine, Andrew M, Rubel, Camille Z, Engle, Keary M, Shi, Bing-Feng

“…Transition-metal-catalyzed, coordination-assisted C­(sp3)–H functionalization has revolutionized synthetic planning over the past few decades as the use of…”
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Synthesis of Axially Chiral Styrenes through Pd‐Catalyzed Asymmetric C−H Olefination Enabled by an Amino Amide Transient Directing Group by Song, Hong, Li, Ya, Yao, Qi‐Jun, Jin, Liang, Liu, Lei, Liu, Yan‐Hua, Shi, Bing‐Feng

“…The atroposelective synthesis of axially chiral styrenes remains a formidable challenge due to their relatively lower rotational barriers compared to the…”
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Atroposelective Synthesis of Conjugated Diene-Based Axially Chiral Styrenes via Pd(II)-Catalyzed Thioether-Directed Alkenyl C–H Olefination by Jin, Liang, Zhang, Peng, Li, Ya, Yu, Xin, Shi, Bing-Feng

“…The efficient stereoselective synthesis of conjugated dienes, especially those with axial chirality, remains a great challenge. Herein, we report the highly…”
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Synthesis of amino acids and peptides with bulky side chains via ligand-enabled carboxylate-directed γ-C(sp 3 )-H arylation by Liu, Lei, Liu, Yan-Hua, Shi, Bing-Feng

“…Amino acids and peptides with bulky side chains are of significant importance in organic synthesis and modern medicinal chemistry. The efficient synthesis of…”
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Editorial: Metabolic Intervention Based on Functional Biomaterial Strategy to Potentiate Cancer Immunotherapy, Volume I by Feng, Bing

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The Impact of Entrepreneurial Passion on Psychology and Behavior of Entrepreneurs by Feng, Bing, Chen, Min

“…In order to study the influence of entrepreneurial passion on entrepreneurs’ psychology and behavior, based on the theory of self-efficacy, a model of…”
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Site‐Selective δ‐C(sp3)−H Alkylation of Amino Acids and Peptides with Maleimides via a Six‐Membered Palladacycle by Zhan, Bei‐Bei, Li, Ya, Xu, Jing‐Wen, Nie, Xing‐Liang, Fan, Jun, Jin, Liang, Shi, Bing‐Feng

“…The site‐selective functionalization of unactivated C(sp3)−H bonds remains one of the greatest challenges in organic synthesis. Herein, we report on the…”
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Synthesis of Chiral Spirolactams via Sequential C−H Olefination/Asymmetric [4+1] Spirocyclization under a Simple CoII/Chiral Spiro Phosphoric Acid Binary System by Yuan, Wen‐Kui, Shi, Bing‐Feng

“…An unprecedented enantioselective synthesis of spiro‐γ‐lactams via a sequential C−H olefination/asymmetric [4+1] spirocyclization under a simple CoII/chiral…”
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Enantioselective Synthesis of Biaryl Atropisomers by Pd‐Catalyzed C−H Olefination using Chiral Spiro Phosphoric Acid Ligands by Luo, Jun, Zhang, Tao, Wang, Lei, Liao, Gang, Yao, Qi‐Jun, Wu, Yong‐Jie, Zhan, Bei‐Bei, Lan, Yu, Lin, Xu‐Feng, Shi, Bing‐Feng

“…The discovery of proper ligands to simultaneously modulate the reactivity and effectively control the stereoselectivity is a central topic in the field of…”
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Pd‐Catalyzed Atroposelective C−H Allylation through β‐O Elimination: Diverse Synthesis of Axially Chiral Biaryls by Liao, Gang, Li, Bing, Chen, Hao‐Ming, Yao, Qi‐Jun, Xia, Yu‐Nong, Luo, Jun, Shi, Bing‐Feng

“…Biaryl atropisomers are of great importance in natural products, pharmaceuticals, and asymmteric synthesis. The efficient synthesis of these chiral scaffolds…”
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Sulfonamide-Promoted Palladium(II)-Catalyzed Alkylation of Unactivated Methylene C(sp3)H Bonds with Alkyl Iodides by Chen, Kai, Shi, Bing-Feng

“…The alkylation of unactivated β‐methylene C(sp3)H bonds of α‐amino acid substrates with a broad range of alkyl iodides using Pd(OAc)2 as the catalyst is…”
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Scalable, Stereocontrolled Formal Syntheses of (+)‐Isoschizandrin and (+)‐Steganone: Development and Applications of Palladium(II)‐Catalyzed Atroposelective C−H Alkynylation by Liao, Gang, Yao, Qi‐Jun, Zhang, Zhuo‐Zhuo, Wu, Yong‐Jie, Huang, Dan‐Ying, Shi, Bing‐Feng

“…Dibenzocyclooctadiene lignans are an interesting class of molecules because of their unique structure based on an axially chiral biaryl moiety as well as their…”
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Total synthesis of natural and pharmaceutical products powered by organocatalytic reactions by Sun, Bing-Feng

“…[Display omitted] Organocatalysis has emerged as the third pillar of modern asymmetric catalysis in the past two decades. Applying organocatalytic reactions in…”
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Synthesis of Chiral Aldehyde Catalysts by Pd‐Catalyzed Atroposelective C−H Naphthylation by Liao, Gang, Chen, Hao‐Ming, Xia, Yu‐Nong, Li, Bing, Yao, Qi‐Jun, Shi, Bing‐Feng

“…Chiral aldehyde catalysis opens new avenues for the activation of simple amines. However, the lack of easy access to structurally diverse chiral aldehyde…”
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