Search Results - "Feng, Bainian"

Chicoric Acid Prevents Neuroinflammation and Neurodegeneration in a Mouse Parkinson's Disease Model: Immune Response and Transcriptome Profile of the Spleen and Colon by Wang, Ning, Li, Rui, Feng, Bainian, Cheng, Yuliang, Guo, Yahui, Qian, He

“…Chicoric acid (CA), a polyphenolic acid compound extracted from chicory and echinacea, possesses antiviral, antioxidative and anti-inflammatory activities…”
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Isoliquiritigenin‐induced vasodilation by activating large‐conductance Ca2+‐activated K+ channels in mouse mesenteric arteries by Ye, Yang, Gao, Mengru, Feng, Lei, Feng, Bainian, Ma, Xin

“…Isoliquiritigenin (ISL) is a flavonoid substance with a chalcone structure, which exerts anti‐tumour, anti‐oxidation and anti‐inflammatory activity. The…”
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Gene Expression Profiling of H9c2 Cells Subjected to H2O2-Induced Apoptosis with/without AF-HF001 by Wang, Guping, Tang, Chunlei, Yan, Guijun, Feng, Bainian

“…Heart failure represents a major health problem. The development of new drugs to treat this condition is essential. We previously discovered that AF-001…”
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Evaluation of the molluscicidal activities of arylpyrrole on Oncomelania hupensis , the intermediate host of Schistosoma japonicum by Xing, Yuntian, Yao, Jiakai, Qu, Guoli, Dai, Jianrong, Feng, Bainian

“…The snail Oncomelania hupensis is the only intermediate host of the highly invasive parasite Schistosoma japonicum . Molluscicide is often used to curb…”
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Zebrafish as a New Model for Phenotype-based Screening of Positive Inotropic Agents by Tang, Chunlei, Xie, Desheng, Feng, Bainian

“…The zebrafish‐based assay is a widely used animal model system for cardiovascular research. In this study, we investigated the cardiac defects caused by…”
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Synthesis and SAR studies of praziquantel derivatives with activity against Schistosoma japonicum by Wang, Wen-Long, Song, Li-Jun, Chen, Xia, Yin, Xu-Ren, Fan, Wen-Hua, Wang, Gu-Ping, Yu, Chuan-Xin, Feng, Bainian

“…The synthesis and structure-activity relationship (SAR) studies of praziquantel derivatives with activity against adult Schistosoma japonicum are described…”
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Gold-Catalyzed Direct Indolation of Tetrahydroisoquinolines by Zhang, Yan, Luo, Sha, Feng, Bainian, Zhu, Chengjian

“…Nitrogen-containing heterocyclic compounds are important motifs of pharmaceuticals and functional materials, and there has been a growing interest in new…”
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1H-2,3-dihydroperimidine derivatives: a new class of potent protein tyrosine phosphatase 1B inhibitors by Wang, Wen-Long, Yang, Dong-Lin, Gao, Li-Xin, Tang, Chun-Lan, Ma, Wei-Ping, Ye, Hui-Hua, Zhang, Si-Qi, Zhao, Ya-Nan, Xu, Hao-Jie, Hu, Zhao, Chen, Xia, Fan, Wen-Hua, Chen, Hai-Jun, Li, Jing-Ya, Nan, Fa-Jun, Li, Jia, Feng, Bainian

“…A series of 1H-2,3-dihydroperimidine derivatives was designed, synthesized, and evaluated as a new class of inhibitors of protein tyrosine phosphatase 1B…”
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Synthesis and antiviral activity of conformational analogues of leucamide A by Wang, Wen-Long, Chen, Hai-Jun, Ma, Wei-Ping, Gu, Min, Fan, Min-Zhi, Li, Jing-Ya, Feng, Bainian, Nan, Fa-Jun

“…In order to study the effect of heterocyclic core conformational state of leucamide A on its anti-influenza virus A activity, five conformational analogues…”
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Gene Expression Profiling of H9c2 Cells Subjected to H2O2-Induced Apoptosis with/without AF-HF001 by Guping Wanga, Chunlei Tanga, Guijun Yanb, Bainian Fenga

“…Heart failure represents a major health problem. The development of new drugs to treat this condition is essential. We previously discovered that AF-001…”
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The TDs/aptamer cTnI biosensors based on HCR and Au/Ti3C2-MXene amplification for screening serious patient in COVID-19 pandemic by Mi, Xiaona, Li, Hui, Tan, Rong, Feng, Bainian, Tu, Yifeng

“…The accurate assay of cardiac troponin I (cTnI) is very important for acute myocardial infarction (AMI), it also can be employed as an effective index for…”
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Pyrazolopyridine inhibitors of B-RafV600E. Part 2: Structure–activity relationships by Wenglowsky, Steve, Ahrendt, Kateri A., Buckmelter, Alex J., Feng, Bainian, Gloor, Susan L., Gradl, Stefan, Grina, Jonas, Hansen, Joshua D., Laird, Ellen R., Lunghofer, Paul, Mathieu, Simon, Moreno, David, Newhouse, Brad, Ren, Li, Risom, Tyler, Rudolph, Joachim, Seo, Jeongbeob, Sturgis, Hillary L., Voegtli, Walter C., Wen, Zhaoyang

“…Structure–activity relationships around a novel series of B-RafV600E inhibitors are reported. The enzymatic and cellular potencies of inhibitors derived from…”
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Solubility Measurements of 2‑(Diacetoxymethyl)-5-nitrofuran in Pure and Binary Mixture Solvents by Xu, Wei, Ma, Ying, Feng, Bainian

“…In this paper, the solubility of 2-(diacetoxymethyl)-5-nitrofuran in pure methanol, 1-propanol, ethyl acetate, N,N-dimethylformamide, tetrahydrofuran,…”
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Gold‐Oxazoline Complex‐Catalyzed Cross‐Dehydrogenative Coupling of Glycine Derivatives and Alkenes by Ni, Minjie, Zhang, Yan, Gong, Tingting, Feng, Bainian

“…A gold‐oxazoline complex‐catalyzed dehydrogenative Povarov/oxidation tandem reaction for the synthesis of decorated quinolines has been developed from glycine…”
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Evaluation of assay technologies for the identification of protein-Peptide interaction antagonists by Kadkhodayan, Saloumeh, Elliott, Linda O, Mausisa, Grace, Wallweber, Heidi Ackerly, Deshayes, Kurt, Feng, Bainian, Fairbrother, Wayne J

“…An increasing number of assay detection technologies are routinely used in small molecule drug discovery and lead optimization. These assays range from…”
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Synthesis and biological evaluation of new series of quinazoline derivatives as EGFR/HER2 dual-target inhibitors by Jiao, Xiaoyu, Zhang, Qing, Zhang, Yue, Shao, Junlan, Ding, Lei, Tang, Chunlei, Feng, Bainian

“…[Display omitted] •New Quinazoline Derivatives were designed and synthesized.•EGFR/HER2 inhibitory activity and in vitro antiproliferative activity were…”
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A New γ‑Glutamyltranspeptidase-Based Intracellular Self-Assembly of Fluorine-18 Labeled Probe for Enhancing PET Imaging in Tumors by Ye, Siqin, Wang, Shijie, Gao, Dingyao, Li, Ke, Liu, Qingzhu, Feng, Bainian, Qiu, Ling, Lin, Jianguo

“…γ-Glutamyltranspeptidase (GGT) is a cell -membrane-associated enzyme which has been recognized as a promising biomarker for the diagnosis of many malignant…”
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An efficient one-pot, three-component synthesis of vinyl sulfones via iodide-catalyzed radical alkenylation by Fan, Weizheng, Su, Jiapeng, Shi, Dongyang, Feng, Bainian

“…An efficient one-pot, three-component synthesis of vinyl sulfones via iodide-catalyzed radical alkenylation using aryl diazonium salts, terminal alkenes and…”
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Immobilizing of oxo-molybdenum complex on cross-linked copolymer and its catalytic activity for epoxidation reactions by Fan, Weizheng, Shi, Dongyang, Feng, Bainian

“…This work describes the immobilization of molybdenum acetylacetonate oxygen (MoO2(acac)2) on cross-linked porous copolymer support via covalent attachment…”
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Au(III)-catalyzed intermolecular amidation of benzylic C-H bonds by Zhang, Yan, Feng, Bainian, Zhu, Chengjian

“…Au(III)-catalyzed intermolecular amidations of benzylic C-H bonds with sulfonamides and carboxamides are described. The protocol with the Au-bipy…”
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