Search Results - "Femling, Jon K."

Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance by Sully, Erin K, Malachowa, Natalia, Elmore, Bradley O, Alexander, Susan M, Femling, Jon K, Gray, Brian M, DeLeo, Frank R, Otto, Michael, Cheung, Ambrose L, Edwards, Bruce S, Sklar, Larry A, Horswill, Alexander R, Hall, Pamela R, Gresham, Hattie D

“…Bacterial signaling systems are prime drug targets for combating the global health threat of antibiotic resistant bacterial infections including those caused…”
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Neutrophil Bleaching of GFP-Expressing Staphylococci: Probing the Intraphagosomal Fate of Individual Bacteria by Schwartz, Jamie, Leidal, Kevin G, Femling, Jon K, Weiss, Jerrold P, Nauseef, William M

“…Successful host defense against bacteria such as Staphylococcus aureus (SA) depends on a prompt response by circulating polymorphonuclear leukocytes (PMN)…”
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Nox2 modification of LDL is essential for optimal apolipoprotein B-mediated control of agr type III Staphylococcus aureus quorum-sensing by Hall, Pamela R, Elmore, Bradley O, Spang, Cynthia H, Alexander, Susan M, Manifold-Wheeler, Brett C, Castleman, Moriah J, Daly, Seth M, Peterson, M Michal, Sully, Erin K, Femling, Jon K, Otto, Michael, Horswill, Alexander R, Timmins, Graham S, Gresham, Hattie D

“…Staphylococcus aureus contains an autoinducing quorum-sensing system encoded within the agr operon that coordinates expression of virulence genes required for…”
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ω-Hydroxyemodin limits staphylococcus aureus quorum sensing-mediated pathogenesis and inflammation by Daly, Seth M, Elmore, Bradley O, Kavanaugh, Jeffrey S, Triplett, Kathleen D, Figueroa, Mario, Raja, Huzefa A, El-Elimat, Tamam, Crosby, Heidi A, Femling, Jon K, Cech, Nadja B, Horswill, Alexander R, Oberlies, Nicholas H, Hall, Pamela R

“…Antibiotic-resistant pathogens are a global health threat. Small molecules that inhibit bacterial virulence have been suggested as alternatives or adjuncts to…”
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Active ascent accelerates the time course but not the overall incidence and severity of acute mountain sickness at 3,600 m by Beidleman, Beth A, Figueiredo, Peter S, Landspurg, Steven D, Femling, Jon K, Williams, Jason D, Staab, Janet E, Buller, Mark J, Karl, J Philip, Reilly, Aaron J, Mayschak, Trevor J, Atkinson, Emma Y, Mesite, Timothy J, Hoyt, Reed W

“…Acute mountain sickness (AMS) typically peaks following the first night at high altitude (HA) and resolves over the next 2-3 days, but the impact of active…”
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Innate Sex Bias of Staphylococcus aureus Skin Infection Is Driven by α-Hemolysin by Castleman, Moriah J, Pokhrel, Srijana, Triplett, Kathleen D, Kusewitt, Donna F, Elmore, Bradley O, Joyner, Jason A, Femling, Jon K, Sharma, Geetanjali, Hathaway, Helen J, Prossnitz, Eric R, Hall, Pamela R

“…Numerous studies have reported sex bias in infectious diseases, with bias direction dependent on pathogen and site of infection. is the most common cause of…”
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Observational Study of Grand Canyon Rim-to-Rim Day Hikers: Determining Behavior Patterns to Aid in Preventive Search and Rescue Efforts by Pearce, Emily A., Jelínková, Lucie, Fullerton, Lynne, Malcolm, Christian J., Heinrich, Hannah L., Norwil, Evan J., Plate, Adam, Hall, Meryn, Bossart, Christopher S., Schaller, Eric, Harrell, Andrew J., Femling, Jon K.

“…Grand Canyon National Park has seen an increase in visitors traversing the canyon from rim to rim (R2R) in a single day. R2R hikers travel over 33.8 km (21 mi)…”
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Nosocomial infections after severe trauma are associated with lower apolipoproteins B and AII by Femling, Jon K, West, Sonlee D, Hauswald, Erik K, Gresham, Hattie D, Hall, Pamela R

“…Infection after severe trauma is a significant cause of morbidity and mortality days to weeks after the initial injury. Apolipoproteins play important roles in…”
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The antibacterial activity of human neutrophils and eosinophils requires proton channels but not BK channels by Femling, Jon K, Cherny, Vladimir V, Morgan, Deri, Rada, Balázs, Davis, A Paige, Czirják, Gabor, Enyedi, Peter, England, Sarah K, Moreland, Jessica G, Ligeti, Erzsébet, Nauseef, William M, DeCoursey, Thomas E

“…Electrophysiological events are of central importance during the phagocyte respiratory burst, because NADPH oxidase is electrogenic and voltage sensitive. We…”
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Synergy between Extracellular Group IIA Phospholipase A2 and Phagocyte NADPH Oxidase in Digestion of Phospholipids of Staphylococcus aureus Ingested by Human Neutrophils by Femling, Jon K, Nauseef, William M, Weiss, Jerrold P

“…Acute inflammatory responses to invading bacteria such as Staphylococcus aureus include mobilization of polymorphonuclear leukocytes (PMN) and extracellular…”
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Commentary by Femling, Jon K., Baca, Justin T.

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Commentary by Femling, Jon K., Baca, Justin T.

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Neutrophil Bleaching of GFP-Expressing Staphylococci: Probing the Intraphagosomal Fate of Individual Bacteria1 by Schwartz, Jamie, Leidal, Kevin G., Femling, Jon K., Weiss, Jerrold P., Nauseef, William M.

“…Successful host defense against bacteria such as Staphylococcus aureus (SA) depends on a prompt response by circulating polymorphonuclear leukocytes (PMN)…”
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Ventilatory And Cardiovascular Acclimatization Remains Unchanged Following Active Versus Passive Ascent To 3600 m: 1730 by Landspurg, Steven D., Figueiredo, Peter S., Atkinson, Emma Y., Driver, Kyla A., Mesite, Timothy J., Beidleman, Beth A., Buller, Mark J., Staab, Janet E., Hoyt, Reed W., Karl, J Philip, Femling, Jon K., Williams, Jason D., Reilly, Aaron J., Mayschak, Trevor J., Martz, Angela M.

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Active Ascent To 3600 m Induces A Plasma Volume Expansion That Likely Exacerbates Acute Mountain Sickness: 1731 by Atkinson, Emma Y., Figueiredo, Peter S., Landspurg, Steven D., Karl, J Philip, Hoyt, Reed W., Buller, Mark J., Staab, Janet E., Femling, Jon K., Williams, Jason D., Reilly, Aaron J., Mayschak, Trevor J., Martz, Angela M., Radcliffe, Patrick N., Pounds, Cornal A., Estrada, Gino F., Beidleman, Beth A.

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Active Ascent Does Not Alter Mood State Compared To Passive Ascent Following Ascent To 3600 m: 1729 by Driver, Kyla A., Figueiredo, Peter S., Landspurg, Steven D., Atkinson, Emma Y., Mesite, Timothy J., Staab, Janet E., Buller, Mark J., Karl, J. Philip, Hoyt, Reed W., Femling, Jon K., Williams, Jason D., Reilly, Aaron J., Mayschak, Trevor J., Martz, Angela M., Beidleman, Beth A.

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Active Ascent Does Not Increase Sleep Disturbances Compared To Passive Ascent To 3600 m: 1737 by Figueiredo, Peter S., Mesite, Timothy J., Landspurg, Steven D., Atkinson, Emma Y., Driver, Kyla A., Staab, Janet E., Buller, Mark J., Hoyt, Reed W., Karl, J. Philip, Femling, Jon K., Williams, Jason D., Reilly, Aaron J., Mayschak, Trevor J., Martz, Angela M., Beidleman, Beth A.

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Active Ascent Does Not Alter Mood State Compared To Passive Ascent Following Ascent To 3600 m: 1729 by Driver, Kyla A., Figueiredo, Peter S., Landspurg, Steven D., Atkinson, Emma Y., Mesite, Timothy J., Staab, Janet E., Buller, Mark J., Karl, J. Philip, Hoyt, Reed W., Femling, Jon K., Williams, Jason D., Reilly, Aaron J., Mayschak, Trevor J., Martz, Angela M., Beidleman, Beth A.

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Active Ascent Does Not Alter Cognitive Performance Compared To Passive Ascent To 3600 m: 1740 by Mesite, Timothy J., Figueiredo, Peter S., Landspurg, Steven D., Atkinson, Emma Y., Driver, Kyla A., Buller, Mark J., Karl, J Philip, Hoyt, Reed W., Staab, Janet E., Femling, Jon K., Williams, Jason D., Reilly, Aaron J., Mayschak, Trevor J., Martz, Angela M., Vangala, Sai, Beidleman, Beth A.

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Active Ascent Does Not Increase Sleep Disturbances Compared To Passive Ascent To 3600 m: 1737 by Figueiredo, Peter S., Mesite, Timothy J., Landspurg, Steven D., Atkinson, Emma Y., Driver, Kyla A., Staab, Janet E., Buller, Mark J., Hoyt, Reed W., Karl, J. Philip, Femling, Jon K., Williams, Jason D., Reilly, Aaron J., Mayschak, Trevor J., Martz, Angela M., Beidleman, Beth A.

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