Search Results - "Femia, Matthew R."
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TOX is a critical regulator of tumour-specific T cell differentiation
Published in Nature (London) (01-07-2019)“…Tumour-specific CD8 T cell dysfunction is a differentiation state that is distinct from the functional effector or memory T cell states 1 – 6 . Here we…”
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Journal Article -
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Mediator subunit MED1 modulates intranuclear dynamics of the thyroid hormone receptor
Published in Journal of cellular biochemistry (01-04-2020)“…The thyroid hormone receptors (TRs) mediate thyroid hormone (T3)‐dependent gene expression. The nuclear import and export signals that direct TR shuttling are…”
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Abstract CN01-03: T cell receptor gene therapy for a public neoantigen derived from mutated PIK3CA, a dominant driver oncogene in breast and endometrial cancers
Published in Molecular cancer therapeutics (01-12-2019)“…Abstract Background: “Public” neoantigens represent immunogenic epitopes encompassing hotspot mutations in driver oncogenes that are also restricted by common…”
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Journal Article