Search Results - "Femenia, T"
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The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior
Published in Molecular psychiatry (01-02-2017)“…Recent studies have revealed that the gut microbiota modulates brain development and behavior, but the underlying mechanisms are still poorly understood. Here,…”
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Toll-like receptor-4 regulates anxiety-like behavior and DARPP-32 phosphorylation
Published in Brain, behavior, and immunity (01-03-2018)“…•The immune receptor TLR4 regulates anxiety and affects social behavior.•Deletion of TLR4 alters the expression of genes involved in anxiety…”
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Pglyrp2 expression in the developing hippocampus
Published in Molecular psychiatry (01-02-2017)Get full text
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Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression
Published in Cell (25-09-2014)“…Depression is a debilitating condition with a profound impact on quality of life for millions of people worldwide. Physical exercise is used as a treatment…”
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Disrupted Neuroglial Metabolic Coupling after Peripheral Surgery
Published in The Journal of neuroscience (10-01-2018)“…Immune-related events in the periphery can remotely affect brain function, contributing to neurodegenerative processes and cognitive decline. In mice,…”
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Dysfunctional hippocampal activity affects emotion and cognition in mood disorders
Published in Brain research (02-10-2012)“…Abstract Mood disorders, such as major depressive disorder (MDD), bipolar disorder and generalized anxiety disorder usually comprise mood related as well as…”
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Voluntary Alcohol Drinking Enhances Proopiomelanocortin Gene Expression in Nucleus Accumbens Shell and Hypothalamus of Sardinian Alcohol-Preferring Rats
Published in Alcoholism, clinical and experimental research (01-01-2013)“…Background Evidence obtained in humans and rodents indicates that beta‐endorphin (encoded by the proopiomelanocortin [POMC] gene) is critical in the regulation…”
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Hippocampal-Dependent Antidepressant Action of the H3 Receptor Antagonist Clobenpropit in a Rat Model of Depression
Published in The international journal of neuropsychopharmacology (01-07-2015)“…Background: Histamine is a modulatory neurotransmitter regulating neuronal activity. Antidepressant drugs target modulatory neurotransmitters, thus ultimately…”
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Immunomodulatory Role of CB2 Receptors in Emotional and Cognitive Disorders
Published in Frontiers in psychiatry (15-04-2022)“…Emotional behavior, memory, and learning have been associated with alterations in the immune system in neuropsychiatric and neurodegenerative diseases. In…”
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Running Opposes the Effects of Social Isolation on Synaptic Plasticity and Transmission in a Rat Model of Depression
Published in PloS one (20-10-2016)“…Stress, such as social isolation, is a well-known risk factor for depression, most probably in combination with predisposing genetic factors. Physical exercise…”
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Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model
Published in The world journal of biological psychiatry (28-05-2019)“…Objectives: The cystine/glutamate antiporter (system xc-) is believed to contribute to nonvesicular glutamate release from glial cells in various brain areas…”
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Hippocampal and prefrontal dopamine D1/5 receptor involvement in the memory-enhancing effect of reboxetine
Published in The international journal of neuropsychopharmacology (01-10-2013)“…Dopamine modulates cognitive functions through regulation of synaptic transmission and plasticity in the hippocampus and prefrontal cortex (PFC). Thus,…”
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Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression
Published in CELL (2015)Get full text
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Methods to evaluate cognitive disorders in animal models
Published in Revista de neurologiá (01-08-2008)“…The increasing prevalence of cognitive dysfunction and dementia associated, among others, to population aging in developed countries has grown a great interest…”
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