Search Results - "Felts de La Roca Soares, Monica"
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Thermal characterization and kinetic study of the antiretroviral tenofovir disoproxil fumarate
Published in Journal of thermal analysis and calorimetry (01-12-2017)“…Tenofovir disoproxil fumarate (TDF) is an antiretroviral belonging to the class of nucleotide analog reverse transcriptase inhibitors, approved for the use…”
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2
Solvent-free synthesis of acetylated cashew gum for oral delivery system of insulin
Published in Carbohydrate polymers (01-03-2019)“…[Display omitted] •Acetylated cashew gum was eco-friendly synthesized by the new solvent-free method.•New NMR spectroscopy methodology for evaluation of degree…”
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Enhanced delivery of fixed-dose combination of synergistic antichagasic agents posaconazole-benznidazole based on amorphous solid dispersions
Published in European journal of pharmaceutical sciences (01-07-2018)“…Posaconazole (PCZ) and benznidazole (BNZ) are known to show synergetic effect in treating the acute and chronic phases of Chagas disease, a neglected parasitic…”
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4
Evaluation of antioxidant potencial of novel CaAl and NiAl layered double hydroxides loaded with olanzapine
Published in Life sciences (1973) (15-08-2018)“…Olanzapine (OLZ), is used in the treatment of bipolar disorder and schizophrenia, diseases that present oxidative stress in their physiopathology. It has low…”
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5
Palygorskite organophilic for dermopharmaceutical application
Published in Journal of thermal analysis and calorimetry (01-03-2014)“…Due to the growing interest of the population in natural treatments, the clays represent a good alternative to the treatment of wounds. Its modification by…”
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A Preformulation Study of a New Medicine for Chagas Disease Treatment: Physicochemical Characterization, Thermal Stability, and Compatibility of Benznidazole
Published in AAPS PharmSciTech (01-09-2010)“…This work aimed the studies of physicochemical characterization, thermal stability, and compatibility of benznidazole (BNZ) drug by spectroscopy (NMR, IR),…”
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A compatibility study of the prototype epiisopiloturine and pharmaceutical excipients aiming at the attainment of solid pharmaceutical forms
Published in Journal of thermal analysis and calorimetry (01-04-2015)“…Epiisopiloturine (EPI) is an alkaloid extracted from pilocarpine production residue that has shown promising activity for neglected illnesses like…”
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8
Amorphous solid dispersions in high-swelling, low-substituted hydroxypropyl cellulose for enhancing the delivery of poorly soluble drugs
Published in International journal of pharmaceutics (25-07-2023)“…[Display omitted] Amorphous solid dispersions (ASDs) based on water-insoluble hydrophilic polymers can sustain supersaturation in their kinetic solubility…”
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Exploring Co-Amorphous Formulations Of Nevirapine: Insights From Computational, Thermal, And Solubility Analyses
Published in AAPS PharmSciTech (12-09-2024)“…This study aimed to assess the formation of nevirapine (NVP) co-amorphs systems (CAM) with different co-formers (lamivudine—3TC, citric acid—CAc, and urea)…”
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10
Microwave-initiated rapid synthesis of phthalated cashew gum for drug delivery systems
Published in Carbohydrate polymers (15-02-2021)“…[Display omitted] •Phthalated cashew gum was synthesized by the microwave-initiated method.•1H NMR spectroscopy was used to assess the degree of substitution…”
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11
Enhancement of dissolution rate through eutectic mixture and solid solution of posaconazole and benznidazole
Published in International journal of pharmaceutics (15-06-2017)“…[Display omitted] Benznidazole (BNZ), the only commercialized antichagasic drug, and the antifungal compound posaconazole (PCZ) have shown synergistic action…”
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Potential of plant-based polysaccharides as therapeutic agents in ulcerogenic diseases of the gastrointestinal tract: A review
Published in International journal of biological macromolecules (01-11-2024)“…In recent years, natural polysaccharides (PSs) have attracted increasing interest because of their remarkable biological properties and potential in various…”
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13
Combining amorphous solid dispersions for improved kinetic solubility of posaconazole simultaneously released from soluble PVP/VA64 and an insoluble ammonio methacrylate copolymer
Published in European journal of pharmaceutical sciences (15-05-2019)“…The aim of this study was to evaluate the potential of combining multiple ASDs based on water soluble and insoluble polymers to reach and maintain poorly…”
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14
Trends in the use of montmorillonite as a delivery system for active substances
Published in Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology (01-07-2023)“…The use of montmorillonite has been investigated as a delivery system for active substances and few studies report discussions and visualization of…”
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15
Evaluation of Microbial Reduction in Root Canals Instrumented with Reciprocating and Rotary Systems
Published in Acta stomatologica croatica (01-12-2015)“…This in vitro study aimed to evaluate the efficacy of the disinfection of root canal systems carried out with Reciproc(TM) and ProTaper Universal(TM) systems…”
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16
Eco-friendly synthesis of phthalate angico gum towards nanoparticles engineering using Quality by Design (QbD) approach
Published in International journal of biological macromolecules (01-11-2021)“…We developed a new hydrophobic polymer based on angico gum (AG), and we produced new nanoparticles to expand the applications of natural polysaccharides in…”
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17
Evolution of pediatric pharmaceutical forms for treatment of Hansen's disease (leprosy)
Published in Expert opinion on therapeutic patents (02-01-2023)“…Leprosy is a neglected, infectious, granulomatous and chronic disease caused by the pathological agent . The course of the disease is more aggressive in…”
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Inclusion complex of methyl-β-cyclodextrin and olanzapine as potential drug delivery system for schizophrenia
Published in Carbohydrate polymers (01-08-2012)“…► Olanzapine, a high cost drug, is the most important antipsychotic drug on the market. ► Olanzapine has low aqueous solubility, affecting its dissolution and…”
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Dissolution performance of acyclovir released from layered double hydroxide clays prepared via spray-drying and lyophilization techniques
Published in Materials letters (15-03-2022)“…•MgAl-Cl-LDH:ACV complexes were prepared via spray-drying or lyophilization.•PXRD analysis and SEM images indicated drug adsorption on the clay surface.•SEM…”
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20
Solid dispersion of efavirenz in PVP K-30 by conventional solvent and kneading methods
Published in Carbohydrate polymers (15-04-2014)“…•Efavirenz (EFV) used as a part of the treatment of first choice in antiretroviral therapy for AIDS has low aqueous solubility and presents problems of…”
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